Janelle Schlossberger and Amanda Marinoff, both 17 and seniors at Plainview-Old Bethpage John F. Kennedy High School on Long Island, split the first prize – a $100,000 scholarship – in the team category for creating a molecule that helps block the reproduction of drug-resistant tuberculosis bacteria.

Isha Himani Jain, 16, a senior at Freedom High School in Bethlehem, Pa., placed first in the individual category for her studies of bone growth in zebra fish, whose tail fins grow in spurts, similar to the way children’s bones do. She will get a $100,000 scholarship.
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Three-quarters of the finalists have a parent who is a scientist. The parents of Alicia Darnell, who won second place, are medical researchers at Rockefeller University, and her maternal grandparents were scientists, too. Isha Himani Jain, who took home the top individual prize, published her first research paper with her father, a professor at Lehigh University, when she was 10 or 11; her mother is a doctor.