Author Archives: curiouscat

Open Science: Looking at Dust

Open access paper: Migration of Contaminated Soil and Airborne Particulates to Indoor Dust.

Indoor dust is a mixture of soil tracked into a residence, particulate matter derived from ambient outdoor air, and importantly, organic matter. Indoor dust is about 40% organic matter by weight in residential housing. Particles tracked into a residence are redistributed on floor surfaces account for over 60% of the dust mass on floors.

Soft Morphing Robot Future

This webcast shows iRobot’s (Romba maker) prototypes for soft flexible robots. The robot uses “jamming” to morph the body which allows animal like locomotion and the ability to reshape the body to squeeze through small and difficult to navigate locations.

Energy Secretary Steve Chu Speaks On Funding Science Research

Energy Secretary Steve Chu (and Nobel Laureate) speaks with Google CEO Eric Schmidt about science research. One of the things Steve Chu is doing is funding high risk experiments that have great potential. This is something that is often said should be done but then people resort to safe investments in research. Taking these risks is a very good idea.

This is another example the remarkable way Google operates. The CEO actually understands science and the public good. Google also provides a huge amount of great material online in the form of webcasts of those speaking at Google. Google behaves like a company run by engineers. Other companies have engineers in positions of power but behave like companies run by any MBAs (whether they are lawyers, accountants, marketers or engineers).

Engineering: Cellphone Microscope

UCLA Professor Aydogan Ozcan‘s invention (LUCAS) enables rapid counting and imaging of cells without using any lenses even within a working cell phone device. He placed cells directly on the imaging sensor of a cell phone. The imaging sensor captures a holographic image of the cells containing more information than a conventional microscope. The CelloPhone received a Wireless Innovations Award from Vodafone

a wireless health monitoring technology that runs on a regular cell-phone would significantly impact the global fight against infectious diseases in resource poor settings such as in Africa, parts of India, South-East Asia and South America.

The CelloPhone Project aims to develop a transformative solution to these global challenges by providing a revolutionary optical imaging platform that will be used to specifically analyze bodily fluids within a regular cell phone. Through wide-spread use of this innovative technology, the health care services in the developing countries will significantly be improved making a real impact in the life quality and life expectancy of millions.
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For most bio-medical imaging applications, directly seeing the structure of the object is of paramount importance. This conventional way of thinking has been the driving motivation for the last few decades to build better microscopes with more powerful lenses or other advanced imaging apparatus. However, for imaging and monitoring of discrete particles such as cells or bacteria, there is a much better way of imaging that relies on detection of their shadow signatures. Technically, the shadow of a micro-object can be thought as a hologram that is based on interference of diffracted beams interacting with each cell. Quite contrary to the dark shadows that we are used to seeing in the macro-world (such as our own shadow on the wall), micro-scale shadows (or transmission holograms) contain an extremely rich source of quantified information regarding the spatial features of the micro-object of interest.

By making use of this new way of thinking, unlike conventional lens based imaging approaches, LUCAS does not utilize any lenses, microscope-objectives or other bulk optical components, and it can immediately monitor an ultra-large field of view by detecting the holographic shadow of cells or bacteria of interest on a chip. The holographic diffraction pattern of each cell, when imaged under special conditions, is extremely rich in terms of spatial information related to the state of the cell or bacteria. Through advanced signal processing tools that are running at a central computer station, the unique texture of these cell/bacteria holograms will enable highly specific and accurate medical diagnostics to be performed even in resource poor settings by utilizing the existing wireless networks.

This is another great example of engineers creating technologically appropriate solutions.

White Paper on Engineering Leadership Education

Engineering leadership education is emerging as a topic in engineering institutions worldwide. But the review of international “best practices” in engineering leadership education says a lack of resources, expertise, and formal networks in the nascent field is causing concern in a profession threatened by a diminishing focus on the notion of the “engineer-as-doer.”

Commissioned by the Bernard M. Gordon-MIT Engineering Leadership Program, the new white paper, Engineering Leadership Education: A Snapshot”© Review”© of International Good”© Practice, reveals that the vast majority of engineering leadership education programs are based within the U.S. and most are relatively new (developed in the last five years). The white paper highlights the distinct divide between the U.S. and the rest of the world in both attitude and approach to engineering leadership education.

“As a sub-discipline, engineering leadership education is not yet on the radar of most engineering education experts outside the U.S.,” said Dr. Edward Crawley, Director of the Bernard M. Gordon-MIT Engineering Leadership Program. “Certainly for many of the programs outside the U.S., there’s some discomfort with the notion of ‘leadership education’, as they feel this concept runs counter to their educational culture of inclusiveness and equality.”

The report was conducted by Dr. Ruth Graham in a series of interviews between September 2008 and March 2009. Dr. Graham investigated more than 40 programs, seeking to provide an insight into current practice, highlight international variations in approach, and identify examples of good practice.

One major ”©current ”©trend”© in ”©engineering”© leadership ”©education”© is ”©the ”©development ”©of”© the ”©students’”© global ”©awareness”© and”© their ”©ability ”©to ”©work ”©on ”©complex”©cross”national”© projects”© – ”©which”© is”© seen ”©by many”© as”© the ”©environment”© within ”©which”© the”© engineering ”©leader”© of ”©the ”©future ”©will ”©need ”©to ”©operate. ”©
Many”© of ”©the ”©programs ”©which ”©were ”©most ”©highly ”©rated ”©by ”©interviewees ”©incorporate ”©some”© global”© elements ”©either ”©through ”©international ”©travel, ”©remote”© link”ups”© with”© overseas”© universities/companies ”©or ”©project”© briefs”© involving ”©an”© international ”©or”© cross”cultural”© context.”© ”©The trend ”©towards”© a ”©more”© ‘global’ ”©view”© of ”©leadership ”©education”© was ”©seen ”©by ”©many ”©of ”©the”© interviewees”© as”© one”© that ”©would”© continue.”©
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Dolphin Delivers Deviously for Rewards

Deep thinkers

At the Institute for Marine Mammal Studies in Mississippi, Kelly the dolphin has built up quite a reputation. All the dolphins at the institute are trained to hold onto any litter that falls into their pools until they see a trainer, when they can trade the litter for fish. In this way, the dolphins help to keep their pools clean.

Kelly has taken this task one step further. When people drop paper into the water she hides it under a rock at the bottom of the pool. The next time a trainer passes, she goes down to the rock and tears off a piece of paper to give to the trainer. After a fish reward, she goes back down, tears off another piece of paper, gets another fish, and so on. This behaviour is interesting because it shows that Kelly has a sense of the future and delays gratification. She has realised that a big piece of paper gets the same reward as a small piece and so delivers only small pieces to keep the extra food coming. She has, in effect, trained the humans.

Her cunning has not stopped there. One day, when a gull flew into her pool, she grabbed it, waited for the trainers and then gave it to them. It was a large bird and so the trainers gave her lots of fish. This seemed to give Kelly a new idea. The next time she was fed, instead of eating the last fish, she took it to the bottom of the pool and hid it under the rock where she had been hiding the paper. When no trainers were present, she brought the fish to the surface and used it to lure the gulls, which she would catch to get even more fish. After mastering this lucrative strategy, she taught her calf, who taught other calves, and so gull-baiting has become a hot game among the dolphins…

Too bad for the poor gulls but this is pretty cool. Plus it serves gulls right, one stole my breakfast a few years ago when I was down in Florida.

Science and Engineering Lectures Online

VideoLectures.Net offers free and open access of a high quality video lectures presented by distinguished scholars and scientists at events like conferences, summer schools, workshops and science promotional events. The portal is aimed at promoting science, exchanging ideas and fostering knowledge sharing by providing high quality didactic contents not only to a scientific community but also to a general public.

Enjoy the great lectures they provide. Also see the Curious Cat directory of science and engineering webcast web sites. There are lots of great presentations available now. The last several years has really seen a huge increase in the valuable webcasts available online.

Low-Cost Multi-touch Whiteboard Using Wii Remote

Using infrared (IR) light pens and the Wii Remote, it is possible to create very low-cost multi-point interactive whiteboards and multi-point tablet displays. Johnny Chung Lee, Carnegie Mellon University. Download the software. Great stuff, it is wonderful to see what people can create with technology.

The Only Known Cancerless Animal

Unlike any other mammal, naked mole rate communities consist of queens and workers more reminiscent of bees than rodents. Naked mole rats can live up to 30 years, which is exceptionally long for a small rodent. Despite large numbers of naked mole-rats under observation, there has never been a single recorded case of a mole rat contracting cancer, says Gorbunova. Adding to their mystery is the fact that mole rats appear to age very little until the very end of their lives.

The mole rat’s cells express p16, a gene that makes the cells “claustrophobic,” stopping the cells’ proliferation when too many of them crowd together, cutting off runaway growth before it can start. The effect of p16 is so pronounced that when researchers mutated the cells to induce a tumor, the cells’ growth barely changed, whereas regular mouse cells became fully cancerous.

“It’s very early to speculate about the implications, but if the effect of p16 can be simulated in humans we might have a way to halt cancer before it starts.” says Vera Gorbunova, associate professor of biology at the University of Rochester and lead investigator on the discovery.

In 2006, Gorbunova discovered that telomerase—an enzyme that can lengthen the lives of cells, but can also increase the rate of cancer—is highly active in small rodents, but not in large ones.

Until Gorbunova and Seluanov’s research, the prevailing wisdom had assumed that an animal that lived as long as we humans do needed to suppress telomerase activity to guard against cancer. Telomerase helps cells reproduce, and cancer is essentially runaway cellular reproduction, so an animal living for 70 years has a lot of chances for its cells to mutate into cancer, says Gorbunova. A mouse’s life expectancy is shortened by other factors in nature, such as predation, so it was thought the mouse could afford the slim cancer risk to benefit from telomerase’s ability to speed healing.

While the findings were a surprise, they revealed another question: What about small animals like the common grey squirrel that live for 24 years or more? With telomerase fully active over such a long period, why isn’t cancer rampant in these creatures?

Researching Direct Brain Interfaces for Text Entry

Adam Wilson posted a status update on the social networking Web site Twitter — just by thinking about it. A UW-Madison biomedical engineering doctoral student, Wilson is among a growing group of researchers worldwide who aim to perfect a communication system for users whose bodies do not work, but whose brains function normally. Among those are people who have amyotrophic lateral sclerosis (ALS), brain-stem stroke or high spinal cord injury.

The interface consists, essentially, of a keyboard displayed on a computer screen. “The way this works is that all the letters come up, and each one of them flashes individually,” says Williams. “And what your brain does is, if you’re looking at the ‘R’ on the screen and all the other letters are flashing, nothing happens. But when the ‘R’ flashes, your brain says, ‘Hey, wait a minute. Something’s different about what I was just paying attention to.’ And you see a momentary change in brain activity.”

The system still is not very quick. However, as with texting, users improve as they practice using the interface. “I’ve seen people do up to eight characters per minute,” says Wilson.

Read full press release