Author Archives: curiouscat

President’s Council of Advisors on Science and Technology

Today, during remarks at the National Academy of Sciences, President Barack Obama announced the President’s Council of Advisors on Science and Technology (PCAST).

PCAST is an advisory group of the nation’s leading scientists and engineers who will advise the President and Vice President and formulate policy in the many areas where understanding of science, technology, and innovation is key to strengthening our economy and forming policy that works for the American people.

President Barack Obama said, “This council represents leaders from many scientific disciplines who will bring a diversity of experience and views. I will charge PCAST with advising me about national strategies to nurture and sustain a culture of scientific innovation.”

PCAST will be co-chaired by John Holdren, Assistant to the President for Science and Technology and Director of the White House Office of Science and Technology Policy; Eric Lander, Director of the Broad Institute of MIT and Harvard and one of the principal leaders of the Human Genome Project; and Harold Varmus, President and CEO of Memorial Sloan-Kettering Cancer Center, former head of the National Institutes of Health and a Nobel laureate.

Members of the council include: Shirley Ann Jackson, Craig Mundie, Eric Schmidt and Ahmed Zewail.

Lenz’s Law in Action: Eddy Current Tubes

Eddy Current Tubes — Drop the Magnets down the tube. An eddy current is set up in a conductor in response to a changing magnetic field. Lenz’s law predicts that the current moves in such a way as to create a magnetic field opposing the change; to do this in a conductor, electrons swirl in a plane perpendicular to the changing magnetic field.

Because the magnetic fields of the eddy currents oppose the magnetic field of the falling magnet; there is attraction between the two fields. Energy is converted into heat. This principle is used in damping the oscillation of the lever arm of mechanical balances.

Engineering Students Increasing at Universities

Engineering suddenly hot at universities

Across the United States, enrollment in engineering programs has risen to levels not seen in three decades. The recession appears to be one factor, as students and their parents look for dependable careers. But some education officials detect a shift in opinion about the profession itself, as global warming and stem-cell research make fields like chemical and bioengineering more than just wise choices for job-seekers – but fashionable ones, too.

Many students are bringing to engineering a heightened sense of social responsibility and a desire “to go out and make a difference in the world,” says Joseph Helble, dean of the Thayer School of Engineering at Dartmouth College in Hanover, N.H., where enrollment in introductory undergraduate courses is 30 percent above the five-year average.

Nationally, enrollment in undergraduate engineering programs rose 3 percent in 2007 and 4.5 percent 2008, according to the American Association of Engineering Education. Meanwhile, enrollment in masters’ degree programs rose 7 percent in 2007 and 2 percent in 2008. In the fall of 2008, 91,489 masters degree students and 403,193 undergraduates were studying engineering at US universities and colleges.

Skeptics note that engineering remains a low priority for US students: Among the 25 top engineer-producing countries, the United States ranks No. 22 on a per capita basis.

Increased engineering education is good news for future economic growth. Hopefully this trend can continue.

Swine Flu: a Quick Overview

World Health Organization on Swine influenza

After reviewing available data on the current situation, Committee members identified a number of gaps in knowledge about the clinical features, epidemiology, and virology of reported cases and the appropriate responses. The Committee advised that answers to several specific questions were needed to facilitate its work.

The Committee nevertheless agreed that the current situation constitutes a public health emergency of international concern.

Based on this advice, the Director-General has determined that the current events constitute a public health emergency of international concern, under the Regulations.

Swine flu: a quick overview–and new New York and Kansas cases by Tara Smith

while the cases in the US have been mild and no deaths have occurred that we’re aware of, it seems in Mexico that young people are dying from this–a group that is typically not hard-hit by seasonal influenza viruses. Readers familiar with influenza and know the history of the 1918 influenza pandemic will recall that the “young and healthy” were disproportionally struck by that virus as well–so this knowledge is currently disconcerting and worrisome, but there are so many gaps in our information as far as what’s really going on in Mexico that it’s difficult to make heads or tails out of this data right now.

Third, is this really a new virus? So few influenza isolates are actually analyzed each year (in proportion to the number of people infected) that we aren’t sure yet whether this is something brand-new, or something that has been circulating at a low level for awhile, but just hadn’t been picked up. After all, H1N1 is a common serotype, so additional molecular testing is needed to determine that it’s “swine flu” versus “human” H1N1.
…
this is a fast-developing story, and it will take much more investigation and field work to determine the true extent of the virus’s spread in the population; to figure out… how efficiently it’s transmitted…

This is very early in the scientific inquiry process looking into what exactly is going on. It is too early to tell how serious a threat this is. The reaction of WHO, CDC though shows they are taking the threat seriously. By far the biggest danger in such situations, is reacting too slowly to serious and contagious threats. If you wait to react until proof exists that the situation is very serious the situation can be almost impossible to control. So you need to react quickly to shut down the spread of the threat, hopefully before it has spread too far.

Evolutionary Robotics

Evolutionary Robotics, chapter of Handbook of Robotics, is interesting and includes a good explanation of the difference between evolution and learning:

Evolution and learning (or phylogenetic and ontogenetic
adaptation) are two forms of biological adaptation that differ in space and time. Evolution is a process of selective reproduction and substitution based on the existence of a population of individuals displaying variability at the genetic level. Learning, instead, is a set of modifications taking place within each single individual during its own life time.

Evolution and learning operate on different time scales. Evolution is a form of adaptation capable of capturing relatively slow environmental changes that

might encompass several generations (e.g., the perceptual characteristics of food sources for a given species). Learning, instead, allows an individual to adapt to environmental modifications that are unpredictable at the generational level. Learning might include a variety of mechanisms that produce adaptive changes in an individual during its lifetime, such as physical development, neural maturation, variation of the connectivity between neurons, and synaptic plasticity. Finally, whereas evolution operates on the genotype, learning affects only the phenotype and phenotypic modifications cannot directly modify the genotype.
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Recent research showed that teams of evolved robots can: (a) develop robust and effective behavior, (b) display an ability to differentiate their behavior so
to better cooperate; (c) develop communication capabilities and a shared communication system.

Iron-breathing Species Isolated in Antarctic for Millions of Years

Graphic showing environment of Antarctic subglacial microbes

Graphic of Blood Falls showing microbial community environment in the Antarctic by Zina Deretsky at NSF)

A reservoir of briny liquid buried deep beneath an Antarctic glacier supports hardy microbes that have lived in isolation for millions of years, researchers report this week. The discovery of life in a place where cold, darkness, and lack of oxygen would previously have led scientists to believe nothing could survive comes from a team led by researchers at Harvard University and Dartmouth College.

Despite their profound isolation, the microbes are remarkably similar to species found in modern marine environments, suggesting that the organisms now under the glacier are the remnants of a larger population that once occupied an open fjord or sea.

“It’s a bit like finding a forest that nobody has seen for 1.5 million years,” says Ann Pearson, Thomas D. Cabot Associate Professor of Earth and Planetary Sciences in Harvard’s Faculty of Arts and Sciences. “Intriguingly, the species living there are similar to contemporary organisms, and yet quite different — a result, no doubt, of having lived in such an inhospitable environment for so long.”

“This briny pond is a unique sort of time capsule from a period in Earth’s history,” says lead author Jill Mikucki, now a research associate in the Department of Earth Sciences at Dartmouth and visiting fellow at Dartmouth’s Dickey Center for International Understanding and its Institute of Arctic Studies. “I don’t know of any other environment quite like this on Earth.”

Chemical analysis of effluent from the inaccessible subglacial pool suggests that its inhabitants have eked out a living by breathing iron leached from bedrock with the help of a sulfur catalyst. Lacking any light to support photosynthesis, the microbes have presumably survived by feeding on the organic matter trapped with them when the massive Taylor Glacier sealed off their habitat an estimated 1.5 to 2 million years ago.
Continue reading →

Ruby on Rails Job Opportunity in DC

I, John Hunter, work for the American Society for Engineering Education as an Information Technology Program Manager. My work on this blog is not associated with ASEE and the opinions I express are mine and not those of ASEE. That said, we are looking for a Ruby on Rails developer at ASEE, in Washington DC.

class Employee < ActiveRecord::Base acts_as_programmer has_many :talents has_and_belongs_to_many :computer_languages after_create :schedule_interview validates_inclusion_of :salary, :in => 60000..80000,
:message => “should be between $60k and $80k a year”
validates_inclusion_of :years_of_experience,
:in => 2..7,
:message => “should be between 2 and 7 years”

validates_presence_of :resume
validates_interest_in :ruby_on_rails
validates_interest_in :agile software development

REQUIRED_LANGUAGES = [“Ruby”,”Perl”,”Python”,”JavaScript”,”Lisp”]

def validate
errors.add_to_base(“You must know one of the languages”) unless
(computer_languages.map{|x| x.name} & REQUIRED_LANGUAGES).size > 0
end

def schedule_interview
self.interviewer = Interviewer.create(
:name => “Keith Mounts”,
:url => “www.asee.org/about/contactASEE.cfm“,
)
save
end

def hire
vacation_days = 15
telecommuting_days_per_week = 0..2
office_location = “dupont circle metro stop, washington, dc”
environment = “friendly”
company = “american society for engineering education”
save
end

end

class ApplyController < ApplicationController def index @employee = Employee.new end def apply @employee = Employee.new if @employee.update_attributes(params[:employee]) flash[:notice] = "Thanks for applying! I'll get back to you very soon!" redirect_to :action => “thanks”
else
render :action => “index”
end
end

end

Modified from job announcement created by Sean Stickle when he was at ASEE. Related: Ruby on Rails Job Opportunity

Artificial Intelligence Finds Ancient Indus Script Matches Spoken Language

Artificial Intelligence Cracks 4,000-Year-Old Mystery by Brandon Keim

An ancient script that’s defied generations of archaeologists has yielded some of its secrets to artificially intelligent computers.
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The Indus script, used between 2,600 and 1,900 B.C. in what is now eastern Pakistan and northwest India, belonged to a civilization as sophisticated as its Mesopotamian and Egyptian contemporaries. However, it left fewer linguistic remains. Archaeologists have uncovered about 1,500 unique inscriptions from fragments of pottery, tablets and seals. The longest inscription is just 27 signs long.
…
They fed the program sequences of four spoken languages: ancient Sumerian, Sanskrit and Old Tamil, as well as modern English. Then they gave it samples of four non-spoken communication systems: human DNA, Fortran, bacterial protein sequences and an artificial language.

The program calculated the level of order present in each language. Non-spoken languages were either highly ordered, with symbols and structures following each other in unvarying ways, or utterly chaotic. Spoken languages fell in the middle.

When they seeded the program with fragments of Indus script, it returned with grammatical rules based on patterns of symbol arrangement. These proved to be moderately ordered, just like spoken languages.

Nanoparticles With Scorpion Venom Slow Cancer Spread

In a, chlorotoxin molecules, colored blue and green, attach themselves to a central nanoparticle. In b, each nanoprobe offers many chlorotoxin molecules that can simultaneously latch on to many MMP-2s, depicted here in yellow, which are thought to help tumor cells travel through the body. In c, over time nanoprobes draw more and more of the MMP-2 surface proteins into the cell, slowing the tumor’s spread. Image from the University of Washington.

University of Washington researchers found they could cut the spread of cancerous cells by 98 percent, compared to 45 percent for the scorpion venom alone, by combining nanoparticles with a scorpion venom compound already being investigated for treating brain cancer.

For more than a decade scientists have looked at using chlorotoxin, a small peptide isolated from scorpion venom, to target and treat cancer cells. Chlorotoxin binds to a surface protein overexpressed by many types of tumors, including brain cancer. Previous research by Miqin Zhang‘s group combined chlorotoxin with nanometer-scale particles of iron oxide, which fluoresce at that size, for both magnetic resonance and optical imaging.

Chlorotoxin also disrupts the spread of invasive tumors — specifically, it slows cell invasion, the ability of the cancerous cell to penetrate the protective matrix surrounding the cell and travel to a different area of the body to start a new cancer. The MMP-2 on the cell’s surface, which is the binding site for chlorotoxin, is hyperactive in highly invasive tumors such as brain cancer. Researchers believe MMP-2 helps the cancerous cell break through the protective matrix to invade new regions of the body. But when chlorotoxin binds to MMP-2, both get drawn into the cancerous cell.

Research showed that the cells containing nanoparticles plus chlorotoxin were unable to elongate, whereas cells containing only nanoparticles or only chlorotoxin could stretch out. This suggests that the nanoparticle-plus-chlorotoxin disabled the machinery on the cell’s surface that allows cells to change shape, yet another step required for a tumor cell to slip through the body.

So far most cancer research has combined nanoparticles either with chemotherapy that kills cancer cells, or therapy seeking to disrupt the genetic activity of a cancerous cell. This is the first time that nanoparticles have been combined with a therapy that physically stops cancer’s spread.

Full press release

Keeping Out Technology Workers is not a Good Economic Strategy

The barriers between countries, related to jobs, are decreasing. Jobs are more international today than 20 years ago and that trend will continue. People are going to move to different countries to do jobs (especially in science, engineering and advanced technology). The USA has a good market on those jobs (for many reasons). But there is nothing that requires those jobs to be in the USA.

The biggest impact of the USA turning away great scientists and engineers will be that they go to work outside the USA and increase the speed at which the USA loses its place as the leading location for science, engineering and technology work. This is no longer the 1960’s. Back then those turned away by the USA had trouble finding work elsewhere that could compete with the work done in the USA. If the USA wants to isolate ourselves (with 5% of the population) from a fairly open global science and engineering job market, other countries will step in (they already are trying, realizing what a huge economic benefit doing so provides).

Those other countries will be able to put together great centers of science and engineering innovation. Those areas will create great companies that create great jobs. I can understand wanting this to be 1960, but wanting it doesn’t make it happen.

You could go even further and shut off science and engineering students access to USA universities (which are the best in the world). That would put a crimp in plans for a very short while. Soon many professors would move to foreign schools. The foreign schools would need those professors, and offer a great deal of pay. And those professors would need jobs as their schools laid off professors as students disappeared. Granted the best schools and best professors could stay in the USA, but plenty of very good ones would leave.

I just don’t think the idea of closing off the companies in the USA from using foreign workers will work. We are lucky now that, for several reasons, it is still easiest to move people from Germany, India, Korea, Mexico and Brazil all to the USA to work on advanced technology projects. The advantage today however, is much much smaller than it was 30 years ago. Today just moving all those people to some other location, say Singapore, England, Canada or China will work pretty well (and 5 years from now will work much better in whatever locations start to emerge as the leading alternative sites). Making the alternative of setting up centers of excellence outside the USA more appealing is not a good strategy for those in the USA wanting science, engineering and computer programming jobs. We should instead do what we can to encourage more companies in the USA that are centralizing technology excellence in the USA.

Comment on Reddit discussion.