Author Archives: curiouscat

High School Inventor Teams @ MIT

Sadly MIT deleted the video after having it live for several years.

Lemelson-MIT InvenTeams is a national grants initiative of the Lemelson-MIT Program to foster inventiveness among high school students. The webcast above shows a high school team presenting a project they completed to create a solution to provide clean water. This stuff is great. I love appropriate technology. I love seeing kids think and create effective solutions to real problems. This is how you get kids to learn – not boring classes (at least kids like me).

The students are passing on the project to students at their school to continue to work on. (MIT TechTV used to have many more presentation by other InvenTeams – not anymore 🙁 ) InvenTeams and MIT deserve a great deal of credit for creating such great learning opportunities and great solutions for the world.

InvenTeams composed of high school students, teachers and mentors are asked to collaboratively identify a problem that they want to solve, research the problem, and then develop a prototype invention as an in-class or extracurricular project. Grants of up to $10,000 support each team’s efforts. InvenTeams are encouraged to work with community partners, specifically the potential beneficiaries of their invention.

Dolphins Using Tools to Hunt

photo of a dolphin with a sponge it uses to hunt

Photograph of dolphin with a sponge it uses to hunt, courtesy of Ewa Krzyszczyk, PLoS, high resolution.

Cool open access research from PLoS One, Why Do Dolphins Carry Sponges?

Tool use is rare in wild animals, but of widespread interest because of its relationship to animal cognition, social learning and culture. Despite such attention, quantifying the costs and benefits of tool use has been difficult, largely because if tool use occurs, all population members typically exhibit the behavior. In Shark Bay, Australia, only a subset of the bottlenose dolphin population uses marine sponges as tools, providing an opportunity to assess both proximate and ultimate costs and benefits and document patterns of transmission.

We compared sponge-carrying (sponger) females to non-sponge-carrying (non-sponger) females and show that spongers were more solitary, spent more time in deep water channel habitats, dived for longer durations, and devoted more time to foraging than non-spongers; and, even with these potential proximate costs, calving success of sponger females was not significantly different from non-spongers. We also show a clear female-bias in the ontogeny of sponging. With a solitary lifestyle, specialization, and high foraging demands, spongers used tools more than any non-human animal. We suggest that the ecological, social, and developmental mechanisms involved likely (1) help explain the high intrapopulation variation in female behaviour, (2) indicate tradeoffs (e.g., time allocation) between ecological and social factors and, (3) constrain the spread of this innovation to primarily vertical transmission.

The dolphins use the sponge to push along the ocean floor and disturb fish, that are hidden. Once the fish start swimming away the dolphin abandons the sponge and catches and eats the fish. Then the dolphin goes back and gets the sponge and continues.

How Antibiotics Kill Bacteria

Since the first antibiotics reached the pharmacy in the 1940s, researchers discovered that they target various pieces of machinery in bacterial cells, disrupting the bacteria’s ability to build new proteins, DNA, or cell wall. But these effects alone do not cause death, and a complete explanation of what actually kills bacteria after they are exposed to antibiotics has eluded scientists.
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The group found that all bactericidal antibiotics, regardless of their initial targets inside bacteria, caused E. coli to produce unstable chemicals called hydroxyl radicals. These compounds react with proteins, DNA, and lipids inside cells, causing widespread damage and rapid death for the bacteria.
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With the results of these two experiments, the researchers were able to identify three major processes implicated in gentamicin-induced cell death: protein transport, a stress response triggered by abnormal proteins in the cell membrane, and a metabolic stress response.

Global Cancer Deaths to Double by 2030

Global Cancer Deaths to Double by 2030 by Salynn Boyles

Cancer deaths are projected to more than double worldwide over the next two decades, largely from a dramatic increase in cancer incidence in low- and middle-income countries driven by tobacco use and increasingly Westernized lifestyles.

A new report from the International Agency for Research on Cancer (IARC) explores the global burden of cancer, which is poised to become the leading cause of death worldwide by 2010. The report predicts that by 2030, 27 million new cancer cases and 17 million cancer deaths will occur each year worldwide. That compares to 12 million new cancers and slightly less than 8 million cancer deaths in 2007.

People really need to stop smoking. And we are pretty lame a society when we inflict such needless disease and death on our fellow humans. Curing millions of cancer patients 20 years from now will be very hard. but it isn’t hard to “cure” millions of them today. We just need people not to pay a lot of money to give themselves cancer by smoking.

Poor Reporting and Unfounded Implications

Correlation is not causation. And reporting of the form, “1 time this happened” and so I report it as though it is some relevant fact, is sad. Take any incident that happened and then state random traits you want to imply there is some relevant link to (blue eyes, red hair, people that watch IT Crowd, people that bought a banana yesterday, tall, overweight, did poorly in math…) and most people will know you are ignorant.

Looking at random data people will find patterns. Sound scientific experimentation is how we learn, not trying to find anything that support our opinions. Statistics don’t lie but ignorant people draw faulty conclusions from data (when they are innumerate – illiteracy with mathematical concepts).

It’s not what the papers say, it’s what they don’t by Ben Goldacre

On Tuesday the Telegraph, the Independent, the Mirror, the Express, the Mail, and the Metro all reported that a coroner was hearing the case of a toddler who died after receiving the MMR vaccine, which the parents blamed for their loss. Toddler ‘died after MMR jab’ (Metro), ‘Healthy’ baby died after MMR jab (Independent), you know the headlines by now.

On Thursday the coroner announced his verdict: the vaccine played no part in this child’s death. So far, of the papers above, only the Telegraph has had the decency to cover the outcome.
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Measles cases are rising. Middle class parents are not to blame, even if they do lack rhetorical panache when you try to have a discussion with them about it.

They have been systematically and vigorously misled by the media, the people with access to all the information, who still choose, collectively, between themselves, so robustly that it might almost be a conspiracy, to give you only half the facts.

Science education is important. Even if people do not become scientists, ignorance of scientific thinking is dangerous. The lack of scientific literacy allows scientifically illiterate leaders to make claims that are lacking scientific merit. And results in people making poor choices themselves, due to their ignorance.

Engineers and Scientists in Congress

I started maintaining a list of Congressmen with PhDs and graduate degrees in science, engineering and math awhile back.

Please comment with any additions that you know of.

The following were re-elected:
Vernon Ehlers, Michigan, physics PhD; Rush Holt, New Jersey, physics PhD; John Olver, Massachusetts, chemistry PhD; Brian Baird, Washington, psychology PhD; Bill Foster, Illinois, physics PhD.

Other scientists, engineers and mathematicians that were reelected include: Ron Paul, Texas, biology BS, MD; Jerry McNerney, California, mathematics PhD; Dan Lipinski, Illinois, mechanical engineering BS, engineering-economic systems MS; Todd Akin, Mississippi, management engineering BS;Cliff Stearns, Florida, electrical engineering BS; Louise Slaughter, New York, microbiology BS; Joe Barton, Texas, industrial engineering BS, Pete Stark, California, engineering BS, Mike Honda, California.

Lost: Nancy Boyda, Kansas (BS chemistry).

Newly elected: Bill Cassidy, Louisiana (BS Biochemistry, MD); Pete Olson, Texas (BA computer science); Kurt Schrader, Oregon (Doctor of Veterinary Medicine); Martin Heinrich, New Mexico (BS engineering), Gregg Harper, Mississippi (BS chemistry), Joseph Cao, Mississippi (BA physics); Brett Guthrie, Virginia (BS mathematical economics); Erik Paulsen, Minnesota, mathematics BA; Parker Griffith, Alabama (BS chemistry, MD); Cynthia Lummis, Wyoming (BS animal science and biology).

Before you leap to the conclusion that scientists are taking over Congress, remember 2 things: 1) I have probably been missing plenty that were in congress already and 2) this is still a total of less than 10% with even a BS in science, math or engineering. I attempted to determine the status of all those newly elected this year.

Please comment, if you know of others in Congress with science and engineering backgrounds. If we get this list to be relative close to accurate then we can start tracking the total representation in congress and see if it is increasing, decreasing or randomly fluctuating over time.

Compounding is the Most Powerful Force in the Universe

A talking head with some valuable info. I remember my father (a statistics professor) getting me to understand this as a small child (about 6 years old). The concept of growth and mathematical compounding is an important idea to understand as you think and learn about the world. It also is helpful so you understand that statistics don’t lie but ignorant people can draw false conclusions from limited data.

It is unclear if Einstein really said this but he is often quoted as saying “compounding is the most powerful force in the universe.” Whether he did or not, understanding this simple concept is a critical component of numeracy (literacy with numbers). Also quoted at times as: “Compound interest is the eighth wonder of the world.” My guess is that people just find the concept of compounding amazing and then attribute quotes about it to Einstein.

I strongly encourage you to watch at least the first 2 segments (a total of 15 minutes). And then take some time and think. Take some time to think about compounding in ways to help you internalize the concepts. You can also read his book: The Essential Exponential For the Future of Our Planet by Albert Bartlett.

The Chip That Designs Itself

The chip that designs itself by Clive Davidson , 1998

Adrian Thompson, who works at the university’s Centre for Computational Neuroscience and Robotics, came up with the idea of self-designing circuits while thinking about building neural network chips. A graduate in microelectronics, he joined the centre four years ago to pursue a PhD in neural networks and robotics.
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To get the experiment started, he created an initial population of 50 random circuit designs coded as binary strings. The genetic algorithm, running on a standard PC, downloaded each design to the Field Programmable Gate Arrays (FPGA) and tested it with the two tones generated by the PC’s sound card. At first there was almost no evidence of any ability to discriminate between the two tones, so the genetic algorithm simply selected circuits which did not appear to behave entirely randomly. The fittest circuit in the first generation was one that output a steady five-volt signal no matter which tone it heard.

By generation 220 there was some sign of improvement. The fittest circuit could produce an output that mimicked the input – wave forms that corresponded to the 1KHz or 10KHz tones – but not a steady zero or five-volt output.

By generation 650, some evolved circuits gave a steady output to one tone but not the other. It took almost another 1,000 generations to find circuits that could give approximately the right output and another 1,000 to get accurate results. However, there were still some glitches in the results and it took until generation 4,100 for these to disappear. The genetic algorithm was allowed to run for a further 1,000 generations but there were no further changes.

See Adrian Thompson’s home page (Department of Informatics, University of Sussex) for more on evolutionary electronics. Such as Scrubbing away transients and Jiggling around the permanent: Long survival of FPGA systems through evolutionary self-repair:

Mission operation is never interrupted. The repair circuitry is sufficiently small that a pair could mutually repair each other. A minimal evolutionary algorithm is used during permanent fault self-repair. Reliability analysis of the studied case shows the system has a 0.99 probability of surviving 17 times the mean time to local permanent fault arrival. Such a system would be 0.99 probable to survive 100 years with one fault every 6 years.

Very cool.

Related: Evolutionary Design – Invention Machine – Evo-Devo

Britain’s Doctors of Innovation

Susannah Fleming, a PhD student at the University of Oxford life sciences interface doctoral training centre. She is developing a monitoring system to assess children when they first present to medical care. Source

Minister of State for Science and Innovation, Lord Drayson, announced the Â£250million (about $370 million) initiative which will create 44 training centres across the UK and generate over 2000 PhD students. They will tackle some of the biggest problems currently facing Britain such as climate change, energy, our ageing population, and high-tech crime.

17 of the centers will put specific emphasis on integrating industrial and business skills with the PhD education. This approach to training has been extensively piloted by EPSRC through a small number of thriving Engineering Doctorate Centres and Doctoral Training Centres in Complexity Science, Systems Biology and at the Life Sciences Interface. This new investment builds on the success of these and will establish a strong group of centres which will rapidly establish a pre-eminent international reputation for doctoral training.

The multidisciplinary centres bring together diverse areas of expertise to train engineers and scientists with the skills, knowledge and confidence to tackle today’s evolving issues. They also create new working cultures, build relationships between teams in universities and forge lasting links with industry.

As I have said before I think countries are smart to invest in their science and technology futures. In fact I believe creating centers of science and technology excellence is a key to future economic wealth.

Full press release: Â£250 Million to Create New Wave of Scientists and Engineers for Britain

One Sneeze, 150 Colds for Commuters

One sneeze, 150 colds for commuters

An analysis of the germs unleashed from a single commuter’s sneeze showed that within minutes they are being passed on via escalator handrails or seats on trains and underground carriages. At the busiest stations, one sneeze not smothered by a tissue or handkerchief will provide enough germs to infect another 150 commuters.
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A single sneeze expels 100,000 droplets of germs into the air at 90mph. Individual droplets get transferred to handles, rails and other areas frequently held or touched. Up to 10 per cent of all commuters will come into contact with an area infected by that one sneeze, Dr Henderson calculated.
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Researchers asked 1,300 workers about their health and found 99 per cent of commuters suffered at least one cold last winter. In contrast, just 58 per cent of those who work from home and 88 per cent of those who walk to work regularly caught a cold last winter.

It is amazing (or maybe not but I find it amazing) how well cold viruses have evolved to have us sneeze and send out personal virus jet packs to spread them all over and let them infect others. It is sad how impolite some people are as they go around potentially infecting hundreds of other people. Partially their ignorance of basic science may also be to blame for their behavior. It is too bad others have to suffer due to their bad manners and ignorance.