Category Archives: Education

Many Great, Free, Online Courses in Science, Engineering and More

The video, above, provides an overview of an online course, Calculus: Single Variable, via coursera from the University of Pennsylvania. This course provides a brisk, entertaining treatment of differential and integral calculus, with an emphasis on conceptual understanding and applications to the engineering, physical, and social sciences.

Robert Ghrist is the Andrea Mitchell University Professor of Mathematics and Electrical & Systems Engineering at the University of Pennsylvania. Coursera offers many courses in all sorts of disciplines including: Introduction to Genetics and Evolution (Duke), Scientific Computing (University of Washington), Principles of Economics for Scientists (California Institute of Technology), Game Theory (Stanford University and The University of British Columbia), A Beginner’s Guide to Irrational Behavior (Dan Ariely, Duke University), The Modern World: Global History since 1760 (University of Virginia), Microeconomics for Managers (University of California, Irvine), Data Analysis (Johns Hopkins University), Fundamentals of Human Nutrition (University of Florida), Algorithms, Part I (Princeton University), The Ancient Greeks (Wesleyan University), Astrobiology and the Search for Extraterrestrial Life (University of Edinburgh) and Epigenetic Control of Gene Expression, (University of Melbourne).

All the classes are free. These courses, and many more, are extremely appealing. I signed up for 2. I would be interested in signing up for much more but I worry about having the time to commit to keeping up with the coursework. I hope the first two go well and I can sign up for more in the future.

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Quick Webcast With a Few Interesting Science Facts

Interesting facts: I didn’t know that we require 13 minerals or that alcoholic beverages contain amounts of all the minerals we need. An amazing fact: the average person walks the equivalent of 3 times around the earth in a lifetime.

The minerals we need (and the recommended daily amount)

Calcium – 1,200 mg
Magnesium – 320 mg
Phosphorus – 700 mg
Potassium – 4.7 g
Sodium – ?
Chloride?

trace amounts needed
Cobalt (as Vitamin B12) – 2.4 mcg
Copper – 1,156 mcg
Iodine – 150 mcg
Iron – 8 mg
Manganese – 1.8 mg
Niacin – 14 mg
Riboflavin – 1.1 mg
Selenium – 55 mcg
Thiamin – 1.1 mg
Zinc – 8 mg
Chromium?, Molybdenum? Fluoride?

Frankly, in my quick looks around the internet I am not sure what they base the claim we need only 13 minerals on. It seems we need trace amounts of more minerals – did they just ignore those not in alcohol?

I couldn’t find good sources confirming just what minerals are needed. Many list some minerals but don’t list others. I am not really sure what the answer is. I am glad I seem to somehow get whatever I need just by eating somewhat healthfully. It is pretty cool we get these things that way. Of course if we didn’t our ancestors wouldn’t have survived to create descendants that finally became us – as they had a much harder time than me (who can just go the restaurant and grocery store and get all sorts of wonderful food).

Circumhorizontal Arcs – Fire Rainbows – Cloud Rainbows

Fire Rainbow, Johor Bahru by John Hunter

Yesterday afternoon I spotted this odd, colorful, spectrum seemingly in a cloud in Johor Bahru, Malaysia. The colors are similar to a rainbow but the prism effect takes on a bit different form than a rainbow as I learned with a bit of searching online. I added a short post to this blog, about the phenomenon a few years ago.

Johor Bahru under a large cloud which is topped with a fire rainbow.

A circumhorizontal arc is an optical phenomenon – an ice-halo formed by plate-shaped ice crystals in high level cirrus clouds. They are also known as “fire rainbows,” if the cloud is at the right angle to the sun, the crystals will refract the sunlight just as when rainbow is created.

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Working as a Software Developer

For most of my career I have been focused on management improvement – helping organizations improve results. Technology plays a big role in that and along the way I found myself becoming a programer for a while; and then a software development program manager. This is a good post on working as a software developer:

reading code is a very important skill. Before a program can be modified, you need to understand what it does, and how it does it. Only then can new functionality be added so it fits in with the existing structure, and without breaking anything. Reading and understanding a program can be a major effort, and one sign of a well-designed program is that it is relatively straight-forward to modify it.
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Write for people first, computer second. The code you write will be read many times in the future (by you, or another developer). The computer doesn’t care how the code is written, so make it as easy as possible to understand for the next person that has to read it. A corollary to this is: don’t be too clever. It’s better to be clear than to be clever.

When there is a compelling need to write for the computer first and people second make sure to document that code well. For example, some code that is extremely dense and complex and confusing but greatly enhances the efficiency of a critical area of code.

I recently wrote a book, Management Matters: Building Enterprise Capability. There are many great things about a career in software development. It certainly is also challenging and not for someone looking for the easiest career but I have seem a higher percentage of happy software developers than I have seen in any other discipline.

Promoting Innovation in Sierra Leone

Another inspirational kid that shows that the potential for human good is much greater than the talking heads and politicians that litter the TV screen so often.

In the video Kelvin says, “That is my aim: to Promote Innovation in Seira Leone, among young people.” See another video as Kelvin explains his homemade battery.

Support these young engineers in Sierra Leone via innovate Salone.

Arduino Introduction Video Tutorial

Arduino is a very cool open source programable hardware engineering initiative. It is great for kids and adults who like to learn and create electronic devices. The Arduino Starter Kit is a great education gift for those interested in such things.

The video explains how to build a basic circuit with the Arduino board, and how to use each of the basic components such as LEDs, switches, and resistors. See more videos on related topics. Massimo Banzi, the co-creator and CEO of Arduino, and seen in the videos, also has a book: Getting Started with Arduino.

Drug Company Funding Taints Published Medical Research

Science provide the opportunity for us to achieve great benefits for society. However, especially in medical research money can make what are already very difficult judgments even less reliable. Add that to a very poor understanding of science in those we elect and you have a dangerous combination. That combination is one of the largest risks we face and need to manage better. I wish we would elect people with a less pitiful appreciation for science but that doesn’t seem likely. That makes doing a better job of managing the conflicts of interest money puts into our current medical research a top priority.

How Drug Company Money Is Undermining Science by Charles Seife

In the past few years the pharmaceutical industry has come up with many ways to funnel large sums of money—enough sometimes to put a child through college—into the pockets of independent medical researchers who are doing work that bears, directly or indirectly, on the drugs these firms are making and marketing. The problem is not just with the drug companies and the researchers but with the whole system—the granting institutions, the research labs, the journals, the professional societies, and so forth. No one is providing the checks and balances necessary to avoid conflicts.
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Peer-reviewed journals are littered with studies showing how drug industry money is subtly undermining scientific objectivity. A 2009 study in Cancer showed that participants somehow survived longer when a study’s authors had conflicts of interest than when the authors were clean. A 1998 study in the New England Journal of Medicine found a “strong association” between researchers’ conclusions about the safety of calcium channel blockers, a class of drugs used to reduce blood pressure, and their financial relationships with the firms producing the drugs.

Most of those in the system have an interest in minimizing an effort to clean this up. It is just more work they don’t want to do. Or it goes directly against their interest (drug companies that want to achieve favorable opinions by buying influence). The main political message in the USA for a couple decades has been to reduce regulation. Allowing research that is tainted because you find regulation politically undesirable is a bad idea. People that understand science and how complex medical research is appreciate this.

Sadly when we elect people that by and large are scientifically illiterate they don’t understand the risks of the dangerous practices they allow. Even if they were scientifically illiterate but understood their ignorance they could do a decent job by getting scientific consultation from experts but they don’t (to an extent they listen to the scientists that those that give them lots of money tell them to which does help make sure those giving the politicians cash have their interests served but it is not a good way to create policy with the necessary scientific thinking needed today).

Solar Powered Water Jug to Purify Drinking Water

Deepika Kurup, a 14-year-old New York student, won the Discovery Education 3M Young Scientist Challenge for her invention of a solar-powered water jug that changes dirty water into purified drinking water. She won the top prize of $25,000.

During “the 5 minutes of my presentation 15 children have died from lack of clean drinking water.”

I am thankful we have kids like this to create solutions for us that will make the world a better place. We rely on hundreds of thousands of such people to use science and engineering methods to benefit society.

Key Indicator for Malignant Melanoma Found

Skin cancer detection breakthrough

The researchers found that certain biochemical elements in the DNA of normal pigment-producing skin cells and benign mole cells are absent in melanoma cells. Loss of these methyl groups — known as 5-hmC — in skin cells serves as a key indicator for malignant melanoma. Loss corresponded to more-advanced stages of melanoma as well as clinical outcome.

Strikingly, researchers were able to reverse melanoma growth in preclinical studies. When the researchers introduced enzymes responsible for 5-hmC formation to melanoma cells lacking the biochemical element, they saw that the cells stopped growing.

“It is difficult to repair the mutations in the actual DNA sequence that are believed to cause cancer,” said Christine Lian, a physician-scientist in the Department of Pathology at BWH and one of the lead authors. “So having discovered that we can reverse tumor cell growth by potentially repairing a biochemical defect that exists — not within the sequence but just outside of it on the DNA structure — provides a promising new melanoma treatment approach for the medical community to explore.”

Because cancer is traditionally regarded as a genetic disease involving permanent defects that directly affect the DNA sequence, this new finding of a potentially reversible abnormality that surrounds the DNA (thus termed “epigenetic”) is a hot topic in cancer research, according to the researchers.

In the United States, melanoma is the fifth most common type of new cancer diagnosis in men and the seventh most common type in women. The National Cancer Institute estimates that in 2012 there will be 76,250 new cases and 9,180 deaths in the United States owing to melanoma.

Thankfully scientists keep making great progress in understanding and finding potential clues to treating cancer. And big gains have been made in treating some cancers over the last few decades. But the research successes remain difficult to turn into effective solutions in treating patients.

I am thankful we have so many scientists doing good work in this difficult and important area (cancer).

Roominate: Inspiring Artists, Engineers and Visionaries

Roominate is a cool new toy created by 3 engineering students aimed at giving young engineers a way to learn, experiment and create. The 3 women used kickstarter to get the funds needed to launch their product. They raised $85,000 (the goal was $25,000).

We’re more than just a toy company. We want to inspire your daughters to be the great artists, engineers, architects, and visionaries of their generation. We intend to give them every tool to reach that potential.

Founders:

Bettina Chen: CalTech BS in Electrical Engineering, masters in Electrical Engineering from Stanford.

Alice Brooks: MIT BS in Mechanical Engineering, currently at Stanford pursuing masters in Mechanical Engineering design.

Jennifer Kessler: Bachelor degree from University of Pennsylvania, currently an MBA student at Stanford.

This is yet another example of entrepreneurship shown by Standford students. The USA is hugely benefited by Stanford (along with a few other schools: MIT, Caltech, etc.). There is little a country can do that is as helpful economically as encouraging the type of entrepreneurship Standford does.