Category Archives: Education

Mojave Desert Tortoises

photo of desert tortoise

But we were very lucky 🙂 We managed to see 5 desert tortoises (Gopherus agassizii) on that particular day, and one of them was spotted on the dirt road (not in the burrow)!

Desert tortoises are thought to live 40 – 60 years. They grow relatively slowly and adult females are larger than adult males (for obvious reasons). They typically breed from April to June and the female tortoises lay between 1 and 11 eggs. Incubation period for eggs varies from 80 to more than 100 days.

Pelf is experiencing a turtle conservation training and tour of the USA (see Turtle Camps in Malaysia). Her blog is doing a great job showing they made a good selection in choosing her for the scholarship.

Cloned Immune Cells Clear Patient’s Cancer

Cloned immune cells cleared patient’s cancer

A patient whose skin cancer had spread throughout his body has been given the all-clear after being injected with billions of his own immune cells. Tests revealed that the 52-year-old man’s tumours, which spread from his skin to his lung and groin, vanished within two months of having the treatment, and had not returned two years later.

Doctors attempted the experimental therapy as part of a clinical trial after the man’s cancer failed to respond to conventional treatments.

The man is the first to benefit from the new technique, which uses cloning to produce billions of copies of a patient’s immune cells. When they are injected into the body they attack the cancer and force it into remission.

There are many more wonderful announcements than wonderful solutions that live up to the hope provided by the announcement. Still this is one in the long line of potentially wonderful treatments. If it turns out to be successful the whole world will benefit which is an example of why I am thankful so many countries are investing in science and technology.

Lancelet Genome Provides Answers on Evolution

Lancelet genome shows how genes quadrupled during vertebrate evolution by Robert Sanders

“If you compare the 23 chromosomes of humans with the 19 chromosomes of amphioxus, you find that both genomes can be expressed in terms of 17 ancestral pieces. So, we can say with some confidence that 550 million years ago, the common ancestor of amphioxus and humans had 17 chromosomal elements.”
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Each of those 17 ancestral segments was duplicated twice in the evolution of vertebrates, after which most of the routine “housekeeping” genes lost the extra copies. Those left, totaling a couple thousand genes, found new functions that, Putnam said, make us different from all other creatures.

“These few thousand genes have been retooled to make humans more elaborate than their simpler ancestors. They are involved in setting up the body plan of an animal and differentiating different parts of the animal,” he said. “The hypothesis, pretty strongly supported by this data, is that the multiplication of this particular kind of gene and differentiation into different functions was important in the formation of vertebrates as we know them.”

“The most exciting thing that the amphioxus genome does is provide excellent evidence for the idea that Ono proposed in 1970, that the human genome had undergone two rounds of whole-genome duplication with subsequent losses,”

A great example of the scientific method in action. It often isn’t a matter of developing a theory one day, testing it the next and learning the outcome the next. The process can take decades for complex matters.

Tracking Down Tomato Troubles

Tracking the bug in tomatoes

David Acheson is the nation’s top food detective, but so far he has met his match in the wily tomato.

With the salmonella scare that has plagued tomatoes, Acheson has faced perhaps his biggest test—at least as far as outbreaks of illness go—since he assumed the newly created “food safety czar” post at the U.S. Food and Drug Administration about a year ago.

That position was born amid a growing concern that the FDA couldn’t get a grip on food safety, as tales of food-borne illnesses multiplied. Now comes salmonella-laden tomatoes that have sickened at least 277 people nationwide, hospitalizing 43.
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The FDA concluded that the tainted tomatoes most likely came from Mexico or a certain part of Florida. The agency managed to narrow down the possible origins of the tainted tomatoes largely by a process of elimination. Based on the timing of their growing seasons and tomato harvests, many states or countries could not be the source of the tomatoes that caused illnesses, so they were deemed safe sources.

Restaurants and food retailers say they are now sourcing tomatoes from places deemed safe by the FDA. The outbreak has been a particularly tough one to crack because it has been so widespread. Illness has shown up in people who frequented a variety of restaurants, and who bought tomatoes at myriad grocery stores.

How Humans Evolved Allergies

Ancient antibody molecule offers clues to how humans evolved allergies

The chicken molecule, an antibody called IgY, looks remarkably similar to the human antibody IgE. IgE is known to be involved in allergic reactions and humans also have a counterpart antibody called IgG that helps to destroy invading viruses and bacteria. Scientists know that both IgE and IgG were present in mammals around 160 million years ago because the corresponding genes are found in the recently published platypus genome. However, in chickens there is no equivalent to IgG and so IgY performs both functions.

Lead researcher, Dr. Rosy Calvert said: “Although these antibodies all started from a common ancestor, for some reason humans have ended up with two rather specialised antibodies, whereas chickens only have one that has a much more general function.
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Professor Brian Sutton, head of the laboratory where the work was done said: “It might be that there was a nasty bug or parasite around at the time that meant that humans needed a really dramatic immune response and so there was pressure to evolve a tight binding antibody like IgE. The problem is that now we’ve ended up with an antibody that can tend to be a little over enthusiastic and causes us problems with apparently innocuous substances like pollen and peanuts, which can cause life-threatening allergic conditions.”

$1 Billion for Life Sciences in Massachusetts

Petri dish for economic growth

So far, the signs are good. The bill commits $500 million for research facilities, infrastructure improvements, and other capital projects; $250 million for tax credits; and $250 million for research grants. The plan is flexible enough to support research at private institutions while making major investments at public universities. Patrick and legislators fended off the most flagrant attempts to divert money into political pet projects with little direct relevance to the biotech industry, such as $49.5 million for a science building at a state college with no graduate science programs.

As I have mentioned many times the centers of scientific excellence are important for economic success. Massachusetts has some great advantages with MIT, Harvard, many biotech companies… but still must continue to focus on staying a center of excellence.

Mathematicians Critique Journal Rankings

Three international math groups joined forces to issue a report last week decrying the use of citation statistics to evaluate scientific journals, research institutions and individual scientists. These statistics, sometimes called “bibliometrics,” measure how frequently a given journal’s articles are cited by other journals.

Read the report on Citation Statistics. This concern is justified. I do have some interest in some of these (and related) statistics but one must always remember their limitations.

TX Active Cement

TX active cement graphic

Industry scrambles to find a ‘greener’ concrete

While Italcemente’s smog-eating cement has been used in Europe for several years, it was released in the United States only in 2007 under the name TX Active. It contains titanium dioxide, which, in the presence of sunlight, acts as a photocatalyer, hastening the decomposition of such pollutants as nitrogen oxides, sulfur oxides, and ozone. TX Active also keeps a building shiny white – a quality admired by architects – by preventing the buildup of pollutants on the surface.

Research suggests that if 15 percent of the surface area of Milan, Italy, were covered in TX Active, air pollutants there could be reduced by 50 percent.

When weighing the environmental effects of concrete, some other benefits need to be included, says Rick Bohan of the Portland Cement Association (PCA), a nonprofit trade group based in Skokie, Ill. For example, the insulation provided by concrete walls combats greenhouse-gas emissions by reducing the energy needed for heating and cooling a building by up to 40 percent compared with wood- and steel-frame structures, according to PCA research.

TXActive Cement graphic from HeidelbergCement

Geek Pad Paper

Geek Pad provides programming, engineering and science students paper with a subtle grid to help organize notes and draw graphs. I don’t exactly see this as revolutionary as the web site claims, but you might find it useful. Plus I like that it was created by a college junior pursuing a B.S. in electronics engineering.

RoboCup German Open 2008

Video of humanoid robot football (soccer) competition in German, April 2008. They are a bit slow but it sure looks like this is a fun area to watch the improvement of robot engineering.