Category Archives: Students

Items for students and others, interested in learning about science and engineering and the application of science in our lives. We post many of the general interest items here.

Cell Signals Webcast

Very cool animation, by Cold Spring Harbor Laboratory and Interactive Knowledge, of the working of the inner workings of our bodies as they react to a cut. If you want to get right to the science, skip the first minute. Providing these types of educational animations is a great way for educational institutions to take advantage of technology to achieve their mission in ways not possible before.

It is annoying how many of those “educational” institutions don’t provide such educational material online (and even take material offline that was online). Have they become more focused on thinking and operating the way they did in 1970 than promoting science education? It is a shame some “educational” institutions have instead become focused on looking backward. I will try to promote those organizations that are providing online science education.

2008 Lemelson-MIT Prize for Invention

photo of Joseph Desimone

The Lemelson-MIT Prize awards $500,000 to mid-career inventors dedicated to improving our world through technological invention and innovation. Joseph M. DeSimone received the 2008 award.

His exposure to polymer science led him to pursue a Ph.D. in chemistry from Virginia Polytechnic Institute and State University in Blacksburg, Va. At the age of 25, DeSimone joined the University of North Carolina at Chapel Hill (UNC) as an assistant professor in chemistry and launched the university’s polymer program with his mentor Dr. Edward Samulski. He resides there today as the Chancellor’s Eminent Professor of Chemistry at UNC, in addition to serving as the William R. Kenan, Jr. Distinguished Professor of Chemical Engineering at North Carolina State University.

Among DeSimone’s notable inventions is an environmentally friendly manufacturing process that relies on supercritical carbon dioxide instead of water and bio-persistent surfactants (detergents) for the creation of fluoropolymers or high-performance plastics, such as TeflonÂ®. More recently, he worked on a team to design a polymer-based, fully bioabsorbable, drug-eluting stent, which helps keep a blocked blood vessel open after a balloon-angioplasty and is absorbed by the body within 18 months.

DeSimone’s newest invention is PRINTÂ® (Particle Replication in Non-wetting Templates) technology, used to manufacture nanocarriers in medicine. At present, DeSimone’s Lab is vested in a variety of projects that also extend beyond medicine, including potential applications for more efficient solar cells and morphable robots. In 2004, DeSimone co-founded Liquidia Technologies with a team of researchers from UNC to make the technology available in the market. Liquidia is using the PRINT technology to develop precisely engineered nanocarriers for highly targeted delivery of biological and small molecule therapeutics to treat cancer and other diseases. DeSimone’s proposed applications for cancer treatment with the PRINT platform was instrumental in UNC landing a grant of $24 million from the National Cancer Institute to establish the Carolina Center for Cancer Nanotechnology Excellence.

“You can do all the innovating you want in the laboratory, but if you can’t get it out of the university walls you do no one any good,” said DeSimone. He instills an entrepreneurial spirit in his students that focuses on the importance of commercializing technology and scientific inventions. One of DeSimone’s greatest accomplishments is his mentorship of more than 45 postdoctoral research associates, 52 Ph.D. candidates, six M.S. theses and 21 undergraduate researchers. Furthermore, he speaks to groups of high school students about the inventive process and encourages them to learn and explore areas that are less familiar to them to broaden their exposure to other disciplines.

A prolific inventor, DeSimone holds more than 115 issued patents with more than 70 new patent applications pending, and he has published more than 240 peer-reviewed scientific articles.

Our Genome Changes as We Age

Our Genome Changes Over Our Lifetime

For the new study, researchers first collected DNA samples collected in 1991 and again between 2002 and 2006 from 600 participants already enrolled in the AGES Reykjavik Study. The AGES study is renowned for its value to genetics research because of the historic isolation and reduced number of genetic “variables” among Iceland’s population, making certain patterns of genetic information easier to identify.

Among the 600, the research team measured the total amount of DNA methylation in each of 111 samples and compared total methylation from DNA collected in 2002 to 2005 to that person’s DNA collected in 1991.

They discovered that in almost one-third of the subjects, methylation changed over that 11-year span, with some gaining DNA methylation and others losing it.

“The key thing this part of the study told us is that levels changed over time, proof of principle that an individual’s epigenetic profile does change with age,” said M. Daniele Fallin, Ph.D., an associate professor of epidemiology at the Johns Hopkins Bloomberg School of Public Health.

Still a puzzle, though, was why or how, Fallin said, “so we wondered whether the tendency to those changes was also inherited, right along with our DNA sequences. That would explain why certain families are more susceptible to certain diseases.”

Transferring Train Passengers Without Stopping

The webcast shows a train transferring passengers without stopping. Essentially passenger modules are picked up and dropped off at each station. Looks pretty cool and would seem to require somewhat complex engineering – which can be a problem as complexity allows for more things to go wrong. Still it looks pretty cool. The sound is not in English but you can see what the idea is.

Inventor rolls out efficient non-stop train system

Taking the Kaohsiung MRT system as an example, Peng says that its maximum speed is 85 kph. Because it must stop at every station, it achieves an average speed over its route of just 35 kph. If the non-stop system were in place, the top velocity of 85 kph could be maintained throughout the system, saving time and energy.

via: trains that pick you up without stopping

Bananas Going

photo of a baboon eating bananas and holding a kitten

I posted on the threat of extinction for bananas. Dan Koeppel has written an excellent book, Banana: The Fate of the Fruit That Changed the World. He also has a great Banana blog with serious and fun posts:

Urgent threat to Africa’s Bananas:

In Uganda, meanwhile, the disease has become so widespread that yields on banana farms have reached dangerously low levels. Acres and acres of crops have been lost, creating a cascade of economic losses in a trading system that spreads from the tiniest villages to Uganda’s cities, all based on the transport and trade of bananas.

The urgency of this cannot be overstated. Uganda and the nations surrounding it absolutely depend on bananas as a staple foodstuff. Millions rely on bananas for survival. And the spread of BXW into Kenya is yet another indicator that this deadly disease is on the march. As with Panama Disease – the wilting fungus that threatens our banana, the Cavendish – BXW (a bacterial malady) is incurable. The difference between the two is that BXW moves faster and threatens, right now, food supplies in nations with fragile governments.
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First, banana diversity. In order to mitigate the spread of disease, the number of kinds of bananas being grown needs to be increased.
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Second, genetic engineering: It is time for the general public to recognize that working at the DNA level is not always a corporate trojan horse into destroying local agriculture and contaminating the environment. This isn’t all about Monsanto. While consumers in the suburbs and Whole Foods stores protest against all GMO foods – while barely knowing what GMO is – they bluntly prevent out legitimate public research that might stop hunger. Time learn that everything has nuance, the disease that are killing the bananas: they work in just two modes: off – and on.

The photos is from a fun post: Baboon Prefers Bananas over Kittens. Thank Goodness.

Refrigeration Without Electricity

Lack of electricity is a serious problem for vaccines and medicines that need to be cooled. It is hard to imagine that this is a problem, living in the USA, but this is still a problem today. As readers of this blog notice I really like appropriate technology solutions that provide real quality of life enhancements for hundreds of millions of people (which undoubtedly is influence by my father).

Bees, Hornets and Wasps

Photo of a bee by Justin Hunter

Bee vs. Hornet vs. Wasp

A bee can generally only sting you once, while hornets and wasps can sting multiple times.
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Bees are fuzzy pollen collectors that almost always die shortly after stinging people (because the stinger becomes embedded in the skin, which prevents multiple stings). Bees don’t die each time they sting, though; the primary purpose of the stinger is to sting other bees, which doesn’t result in the loss of the stinger.

Wasps are members of the family Vespidae, which includes yellow jackets and hornets. Wasps generally have two pairs of wings and are definitely not fuzzy. Only the females have stingers, but they can sting people repeatedly.

Hornets are a small subset of wasps not native to North America (the yellow jacket is not truly a hornet). Somewhat fatter around the middle than your average wasp, the European hornet is now widespread on the East Coast of the U.S. Like other wasps, hornets can sting over and over again and can be extremely aggressive.

Photo by Justin Hunter

The Technology Job Market is Strong

Technology: It’s Where the Jobs Are by Arik Hesseldahl, Business Week:

Here’s a hint for high school graduates or college students still majoring in indecision: Put down that guitar or book of poetry and pick up a laptop. Study computer science or engineering
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Seattle added a net 7,800 jobs [in 2006], followed by the New York and Washington (D.C.) metro areas, which added more than 6,000 jobs apiece. The fastest-growing area on a percentage basis was the combined metro area of Riverside-San Bernardino, Calif., which saw its tech-employment figures grow by 12%.
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The highest concentration of technology workers – 286 for every 1,000 workers – was in, no surprise, Silicon Valley. Boulder, Colo., came in second, with 230, and Huntsville, Ala.; Durham, N.C.; and Washington rounded out the top five in density.

Now for the answer to the question on everyone’s mind: Where are the highest salaries? That would be Silicon Valley, where the average tech worker is paid $144,000 a year. That’s nearly double the $80,000 national average for tech jobs.
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More than 850,000 IT jobs will be added during the 10-year period ending in 2016, which would be a rise of 24%. Add all the jobs that will replace retiring workers, and the total increase could be a tidy 1.6 million. That means one job in every 19 created over the course of the next decade will be in technology.

And while demand for tech-savvy employees is certainly multiplying, another survey, this one from the Computing Research Assn. and released in March, found a 20% drop in the number of students completing degrees in computer-related fields, and the number of students enrolling in these programs is the lowest it’s been in 10 years, as far back as the data go.

Cost Efficient Solar Dish by Students

Solar Energy Dish

Low-cost system could revolutionize global energy production

A team led by MIT students this week successfully tested a prototype of what may be the most cost-efficient solar power system in the world – one team members believe has the potential to revolutionize global energy production.

The system consists of a 12-foot-wide mirrored dish that team members have spent the last several weeks assembling. The dish, made from a lightweight frame of thin, inexpensive aluminum tubing and strips of mirror, concentrates sunlight by a factor of 1,000 – creating heat so intense it could melt a bar of steel.

To demonstrate the system’s power, Spencer Ahrens, who just received his master’s in mechanical engineering from MIT, stood in a grassy field on the edge of the campus this week holding a long plank. Slowly, he eased it into position in front of the dish. Almost instantly there was a big puff of smoke, and flames erupted from the wood. Success!

Burning sticks is not what this dish is really for, of course. Attached to the end of a 12-foot-long aluminum tube rising from the center of the dish is a black-painted coil of tubing that has water running through it. When the dish is pointing directly at the sun, the water in the coil flashes immediately into steam.

Someday soon, Ahrens hopes, the company he and his teammates have founded, called RawSolar, will produce such dishes by the thousands. They could be set up in huge arrays to provide steam for industrial processing, or for heating or cooling buildings, as well as to hook up to steam turbines and generate electricity. Once in mass production, such arrays should pay for themselves within a couple of years with the energy they produce.

“This is actually the most efficient solar collector in existence, and it was just completed,” says Doug Wood, an inventor based in Washington state who patented key parts of the dish’s design–the rights to which he has signed over to the student team.

Great job students. Good luck with RawSolar. Photo (by David Chandler): Matt Ritter shows steam coming from the return hose after passing through the coil above the solar dish.

Kudzu Biofuel Potential

Kudzu Gets Kudos as a Potential Biofuel

The kudzu vine, also known as “the plant that ate the South,” was brought from eastern Asia in 1876 and can grow more than 6.5 feet a week. Its starchy roots plunge deep into the soil, and just a fragment of the plant remaining in the ground is enough to allow it to come back next season.

“Kudzu is just a large amount of carbohydrate sitting below ground waiting for anyone to come along and dig it up,” Sage said. “The question is, is it worthwhile to dig it up?”
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The roots were by far the largest source of carbohydrate in the plant: up to 68 percent carbohydrate by dry weight, compared to a few percent in leaves and vines.

The researchers estimate that kudzu could produce 2.2 to 5.3 tons of carbohydrate per acre in much of the South, or about 270 gallons per acre of ethanol, which is comparable to the yield for corn of 210 to 320 gallons per acre. They recently published their findings in Biomass and Bioenergy.

Crucial to making the plan work would be figuring out whether kudzu could be economically harvested, especially the roots, which can be thick and grow more than six feet deep. To balance this expense, Sage said, the plant requires zero planting, fertilizer or irrigation costs.