Category Archives: Health Care

Treadmill Desks

The participants were able to use the computer while walking without falling or injuring themselves. In fact, they enjoyed it so much, they wanted to keep the walking desks even after the study ended.
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Findlay got the idea from Mayo Clinic researcher James Levin, a co-author of the BJSM study who has been touting the benefits of his walking desk for years.

I must admit I like to think this idea would be work, but am a bit skeptical. I did switch to a job a few years back where I really just sat at my desk all day and would get tired. Previously I had walked around a fair amount going to see people… Someone suggested that getting some activity at lunch would help me feel more energized. It worked. If nothing else walk around at lunch.

Well, most of us in the corporate world feel like rats on a treadmill, so we might as well make the figurative literal…

Great comment on the post. Many of the other comments state categorically this cannot work. I wonder why they think they know what will work for everyone? I am skeptical but that is not the same thing as being sure this can’t work – I think being open to testing out ideas (especially ones that already have studies that claim they work) is a good thing. I would love to try it out myself (though given my skepticism I wouldn’t want to pay up to buy the equipment 🙂 ).

Genetic Information Nondiscrimination Act

I agree with restricting the use of genetic information for things like insurance – US to outlaw corporate prejudice based on genes:

Soon it will be illegal to deny US citizens jobs or insurance simply because they have an inherited illness, or a genetic predisposition to a particular disease.

On 25 April, the House of Representatives voted 420 to 3 to pass the Genetic Information Nondiscrimination Act (GINA). The Senate is expected to endorse the act within a few weeks, which is also supported by President Bush. “I am so stunned by the majority,” says Sharon Terry, president of the Genetic Alliance, a charity lobbying for the rights of people with inherited illnesses.

Genetic information can provide valuable information about risks. It is not often that I am for saying people should be prohibited from using information that would aid them in making better decisions. However it can be the best public policy to require insurance companies to be prohibited from using information that would allow them to better access risks and price insurance accordingly. So those that know they have such genetic risks will be paying less than they would if the insurance companies were allowed to use that information and everyone else will pay more (to cover for those with the increased risk). I think that is the best policy for the society. However it is not really about outlawing corporate prejudice it is about saying that we will have everyone is society share the cost of risks rather than those that can be identified as greater health risks.

Thinking this is about preventing bad corporate behavior seems to me an attempt to change the focus of the real issue. And that is not a good idea because this is a complex area that we are going to have to make a wide number of decisions about as a society. Pretending the issue is simple does society a disservice. This is an large economic issue and what choices various societies decided to make will be debated extensively for quite some time I believe..

Related: Improving the heath care system posts (from our management blog) – post about health care (from this blog)

Hacking Your Body’s Bacteria

Hacking Your Body’s Bacteria for Better Health by Brandon Keim

In sheer numbers, bacterial cells in the body outnumber our own by a factor of 10, with 50 trillion bacteria living in the digestive system alone, where they’ve remained largely unstudied until the last decade. As scientists learn more about them, they’re beginning to chart the complex symbiosis between the tiny bugs and our health.

“The microbes that live in the human body are quite ancient,” says NYU Medical Center microbiologist Dr. Martin Blaser, a pioneer in gut microbe research. “They’ve been selected (through evolution) because they help us.” And it now appears that our daily antibacterial regimens are disrupting a balance that once protected humans from health problems, especially allergies and malfunctioning immune responses.

Fruit Better Than Vitamins

Fruit proves better than vitamin C alone. Tests show that it isn’t just the vitamin that protects the body.

Other nutrition researchers have suggested that sugars in juice interact with vitamin C to generate the antioxidant effect2. But Guarnieri suspects that the phytochemicals found in oranges (cyanidin-3-glucoside, flavanones and carotenoids) are the substances that need further study. “But how they are interacting is still anyone’s guess,” she adds.

Eat Less Salt – Save Your Heart

Reducing salt cuts cardiovascular disease risk:

Cutting back on salt intake could lower the risk of developing heart disease by 25 per cent, in addition to lower blood pressure benefits, say researchers who studied people with borderline high blood pressure. Researchers in the U.S. looked at more than 3,000 people in two trials with pre-hypertension who reduced their sodium intake by 25 per cent to 35 per cent, compared with control groups that did not.

Cut Heart Risk by Eating Less Salt:

Last summer, the American Medical Association (AMA) called for a minimum 50% reduction in sodium in processed foods, fast foods, and non-fast-food restaurant meals within a decade. The group also called on the FDA to work harder to educate consumers about the health risks associated with a high-sodium diet.

“The average American is eating three times as much salt as is healthy every day — the equivalent of 2 to 3 teaspoons instead of no more than 1,” he says. “The assumption tends to be, ‘If I don’t use my salt shaker much, I’m probably OK,’ but that just isn’t true.”

$600 Million for Basic Biomedical Research

Howard Hughes Medical Institute (HHMI) will hold a national competition for investigators that will result in an investment of at least $600 million in basic biomedical research. Up to 50 new researchers will be selected by spring 2008. HHMI Announces New Open Competition:

HHMI seeks applications from outstanding scientists studying biomedical problems in a broad array of disciplines, including not only biology and medicine, but related areas of chemistry, physics, engineering and computational biology. This competition is open to early career stage scientists at approximately 200 eligible institutions.
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HHMI values innovation and encourages its investigators to extend the boundaries of science. By appointing scientists as Hughes investigators — rather than awarding research grants — HHMI is guided by the principle of “people, not projects.” HHMI investigators have the freedom to explore and, if necessary, to change direction in their research. Moreover, they have support to follow their ideas through to fruition — even if that process takes many years.
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This new competition represents the first time that HHMI has opened up a general competition to the direct application process. In the past, faculty members had to be nominated by their institutions for HHMI investigator positions.

More details and apply via: 2008 HHMI Investigator Competition.

Universal Blood

Universal Blood by Katherine Bourzac:

Red blood cells have complex sugars on their surfaces; it is these sugars that determine whether the blood is type A, B, O, or both A and B. People with type A red blood cells carry antibodies against type B blood cells. If they are given a transfusion of type B red blood cells, their body will attack and kill the cells. Similarly, people with type B blood will mount an immune attack against a transfusion of type A blood.

Researchers led by Henrik Clausen of the University of Copenhagen have discovered two enzymes that efficiently chop the A and B sugars off of red blood cells, making them universal. The company ZymeQuest, based in Beverly, MA, has licensed the enzymes and developed a machine that can simultaneously treat eight units of blood with the enzymes in 90 minutes.

$500 Million to Reduce Childhood Obesity in USA

$500-Million Commitment to Reverse Childhood Obesity in U.S.:

The Robert Wood Johnson Foundation (RWJF) today announced it will commit at least $500 million over the next five years to tackle one of the most urgent public health threats facing our nation: childhood obesity. This is the largest commitment by any foundation to this issue. The Foundation’s goal is to reverse the epidemic of childhood obesity in the United States by 2015.

During the past four decades, obesity rates have soared among all age groups, more than quadrupling among children ages 6 to 11. Today, more than 33 percent of children and adolescents—approximately 25 million kids—are overweight or obese.
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In addition to the toll on our nation’s health, obesity also poses a tremendous financial threat to our economy and our health care system. It’s estimated that the obesity epidemic costs our nation $117 billion per year in direct health care costs and lost productivity. Childhood obesity alone carries a huge price tag-up to $14 billion per year in direct health care costs to treat kids.
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The Foundation will focus on improving access to affordable healthy foods and opportunities for safe physical activity in schools and communities.

Drug-resistant Flu Virus

Drug-resistant flu virus emerges in untreated patients:

The emergence of drug-resistant influenza was documented in a study of Japanese patients. It is a clear early warning that flu viruses may be beginning to outwit what are now highly effective drugs, says Yoshihiro Kawaoka, a University of Wisconsin-Madison virologist and the senior author of the new JAMA study.

“There is urgent need to develop new kinds of antivirals,” says Kawaoka, an internationally recognized authority on influenza. “This is the first report that drug-resistant influenza B virus may be transmitting in the community.”

Neuroengineers Use Light to Silence Overactive Neurons

MIT neuroengineers’ pulsing light silences overactive neurons:

The work takes advantage of a gene called halorhodopsin found in a bacterium that grows in extremely salty water, such as the Great Salt Lake in Utah. In the bacterium, Natronomas pharaonis, the gene codes for a protein that serves as a light-activated chloride pump, which helps the bacterium make energy.

When neurons are engineered to express the halorhodopsin gene, the researchers can inhibit their activity by shining yellow light on them. Light activates the chloride pumps, which drive chloride ions into the neurons, lowering their voltage and silencing their firing.
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The group also plans to use the new method to study neural circuits. Last year, Boyden devised a technique to stimulate neurons by shining blue light on them, so with blue and yellow light the researchers can now exert exquisite control over the stimulation and inhibition of individual neurons. Learning more about the neural circuits involved in epilepsy could help scientists develop devices that can predict when a seizure is about to occur, allowing treatment (either shock or light) to be administered only when necessary, Boyden said.