Category Archives: Life Science

NSF Awards $50 Million for Collaborative Plant Biology Project

The National Science Foundation (NSF) today announced a $50 million award to a University of Arizona-led team to create the first national cyberinfrastructure center to tackle global “grand challenge” plant biology questions that have great implications on larger questions regarding the environment, agriculture, energy and the very organisms that sustain our existence on earth. The five-year project, dubbed the iPlant Collaborative, potentially is renewable for a second five years for a total of $100 million.

Like no other single research entity, the iPlant Collaborative will provide the capacity to draw upon resources and talent in remote locations and enable plant scientists, computer scientists and information scientists from around the world for the first time ever to collaboratively address questions of global importance and advance all of these fields. It will bring together and leverage the resources and information generated through the National Plant Genome Initiative, enabling more breadth and depth of research in every aspect of plant science.

“We are confident in the positive returns of this substantive investment in basic research,” said NSF Director Arden L. Bement. “The iPlant Collaborative will harness the best and the brightest scholars and research in plant biology in order to tackle some of the profound issues of our day and for our future. Challenges that may need plants for solutions include addressing the impacts of climate change, dwindling oil supply, decreasing agricultural land area, increasing population and environmental degradation.”
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Surprising New Diabetes Data

But these measures are only surrogates for disease. And in many cases, the connection between “better” numbers and better health is tenuous. In the case of cholesterol, many people won’t see a health benefit from lower numbers.

Now comes yet another sobering reminder that lowering a surrogate marker doesn’t necessarily bring better health. On Feb. 6, the National Institutes of Health announced it was halting a key trial for diabetes. Researchers had hoped the trial, dubbed ACCORD (Action to Control Cardiovascular Risk in Diabetes), would show that more aggressive lowering of blood sugar would significantly reduce deaths. Instead, the opposite happened. More people in the intensive treatment group died than in the group getting standard care. “A thorough review of the data shows that the medical treatment strategy of intensively reducing blood sugar below current clinical guidelines causes harm in these…patients,” says Dr. Elizabeth Nabel, director of the National Heart, Lung & Blood Institute.

Scientific study often results in less than clear conclusions, especially in complex systems. There is great difficulty understanding what is actually going on, what interactions are present, what factors are significant, etc.. One of the great problems with the low level of scientific literacy in the USA is so many people think science is about simple absolute truth.

Scientific inquiry, especially related to health care, must attempt to gain insights from confusing signals. To gain scientific literacy one must understand basics concepts, like data is a proxy for what you aim to understand. To understand yourself you need to accept that science is not math. For a long time we are going to have to do our best to build up our understanding of human health (and other complex systems) as best we can. We need to be able to sort out what are solid conclusion, what are guesses, what seem like reasonable explanation and what level of confidence we can have in statements.

It is not enough to learn facts we need to be able to think scientifically and comprehend the subtleties surrounding the advances in scientific understanding. Some criticize newspapers and popular science for providing too simplistic a view of new scientific knowledge. While this can be a problem I really see the problem much more serious if people read obviously overly simplistic articles and don’t understand that it is just scratching the surface. The reader needs to take responsibility too. I enjoy many great articles that gloss over many of the details but provide a quick view of intriguing new breakthroughs.

Cancer Killing Ideas From Honeybees

Honeybee Weapon in War on Cancer

No, researchers haven’t found a beehive-based cure (though major royal jelly, the wondrous protein concoction that turns lowly workers into queens, may have anti-cancer properties.) But bee colonies experience their own type of cancer, and maybe human researchers can learn from their victories.
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Like Amdam said, it’s not clear how the honeybees won. Perhaps the successful colonies produced bees adapted to noticing the intruder; perhaps it produced individual bees whose interactions caused some sort of superorganism-wide shift. And maybe when we figure that out, we’ll have some fresh ideas for fighting cancer — maybe not for tweaking our own cells, but for customized nanomolecule cancer hunters.

Nature Recreation Declining

Glacier National Park photo by John Hunter

Photo looking north across Lake McDonald from my Village Inn balcony in Glacier National Park, by John Hunter.

Do people still care about nature

Nature recreation worldwide — from camping, hunting and fishing to park visitation — has declined sharply since the 1980s
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The study examines data from the United States, Japan and Spain on everything from backpacking to duck hunting…that correlated a decline in visits to U.S. National Parks with an increase in television, video game and Internet use.
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The decline in some nature use seems to be accelerating, such as U.S. state park and national forest visits, as well as fishing. Others show a more steady decline, such as U.S. and Japanese national park visits and U.S. Bureau of Public Lands visits. Most reliable long-term per capita visitation measures of nature recreation peaked between 1981 and 1991. They’ve declined about 1.2 percent per year since then, and have declined a total of between 18 percent and 25 percent.
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Other research shows that the time children spend in nature — particularly the activities we looked at in this study – determines their environmental awareness as adults. We recently wrote a review paper looking at this phenomenon as well as at the effects of videophilia on childhood development. These effects are substantial and include obesity, attentional disorders, lack of socialization and poor academic performance.

I must say I am surprised by this. My visits to national parks have led me to believe the attendance was increasing but that seems to be wrong. The National Parks Service has a simple web tool to view visits to US national parks by year. Go visit great parks, here are some photos from my trips: Grand Teton National Park, Rocky Mountain National Park, Shenandoah National Park and Grand Canyon National Park.

The World’s Hottest Chili

The World’s Hottest Chili:

The standard measure for such things is the Scoville Heat Unit, or SHU, named after Wilbur Lincoln Scoville, a chemist who in 1912 developed a method of assessing the heat given off by capsaicin, the active ingredient in chili peppers. JalapeÃ±o peppers measure about 5,000 SHUs. The bhut jolokia tops a million.
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Food scientists speculate that hot chilies have an unexpected side effect that boosts their popularity. A publication of the Brooklyn Botanical Garden in New York described it this way: “When capsaicin comes into contact with the nerve endings in the tongue and mouth, pain messengers, called neurotransmitters, are sent to the brain in a panic. The brain, mistakenly perceiving that the body is in big trouble, responds by turning on the waterworks to douse the flames. The mouth salivates, the nose runs and the upper body breaks into a sweat. The heart beats faster and the natural painkiller endorphin is secreted. In other words, you get a buzz.”

Genetic Research Suggests Cats ‘Domesticated Themselves’

Why Do Cats Hang Around Us? (Hint: They Can’t Open Cans), Washington Post

The findings, drawn from an analysis of nearly 1,000 cats around the world, suggest that the ancestors of today’s tabbies, Persians and Siamese wandered into Near Eastern settlements at the dawn of agriculture. They were looking for food, not friendship.

They found what they were seeking in the form of rodents feeding on stored grain. They stayed for 12 millennia, although not without wandering off now and again to consort with their wild cousins. The story is quite different from that of other domesticated animals: cattle, sheep, goats, horses

Rainforests

John Hunter in Costa Rica

Facts about Rainforests by The Nature Conservancy

Covering less than 2 percent of the Earth’s total surface area, the world’s rainforests are home to 50 percent of the Earth’s plants and animals.
Seventy percent of the plants identified by the U.S. National Cancer Institute as useful in the treatment of cancer are found only in rainforests.
Less than one percent of the tropical rainforest species have been analyzed for their medicinal value.
Originally, 6 million square miles of tropical rainforest existed worldwide. But as a result of deforestation, only 2.6 million square miles remain.
At the current rate of tropical forest loss, 5-10 percent of tropical rainforest species will be lost per decade.
Every second, a slice of rainforest the size of a football field is mowed down. That’s 86,400 football fields of rainforest per day, or over 31 million football fields of rainforest each year.

Photo of John Hunter in Costa Rican rain forest, by Justin Hunter.

Jumping Savannah Cat

The Savannah cat breed is from the mating of a male African serval cat to a female domestic cat. The serval grows to from 9 to 20 kg (20-44 lbs) and lives 12-20 years in the wild. It is closely related to the African Golden Cat and the Caracal. The cats in the webcast are Savannahs.

Swimmers’ Sunscreen Killing Off Coral

Swimmers’ Sunscreen Killing Off Coral Ker Than for National Geographic News:

Four commonly found sunscreen ingredients can awaken dormant viruses in the symbiotic algae called zooxanthellae that live inside reef-building coral species. The chemicals cause the viruses to replicate until their algae hosts explode, spilling viruses into the surrounding seawater, where they can infect neighboring coral communities.

Zooxanthellae provide coral with food energy through photosynthesis and contribute to the organisms’ vibrant color. Without them, the coral “bleaches”—turns white—and dies. “The algae that live in the coral tissue and feed these animals explode or are just released by the tissue, thus leaving naked the skeleton of the coral,” said study leader Roberto Danovaro of the Polytechnic University of Marche in Italy.

The researchers estimate that 4,000 to 6,000 metric tons of sunscreen wash off swimmers annually in oceans worldwide, and that up to 10 percent of coral reefs are threatened by sunscreen-induced bleaching.

Fight to curtail antibiotics in animal feed

Consumer advocates have been campaigning for years to curb the use of antibiotics in agriculture, citing studies that show that 70 percent of all U.S. antibiotics are administered in low doses – not to treat disease, but to promote the growth of pigs, sheep, chicken and cattle.
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But as early as 1963, British researchers tied the emergence of drug-resistant strains of salmonella in humans to antibiotics fed to cattle.