Category Archives: Research

The Calorie Delusion

The calorie delusion: Why food labels are wrong

Nutritionists are well aware that our bodies don’t incinerate food, they digest it. And digestion – from chewing food to moving it through the gut and chemically breaking it down along the way – takes a different amount of energy for different foods. According to Geoffrey Livesey, an independent nutritionist based in Norfolk, UK, this can lower the number of calories your body extracts from a meal by anywhere between 5 and 25 per cent depending on the food eaten.
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Dietary fibre is one example. As well as being more resistant to mechanical and chemical digestion than other forms of carbohydrate, dietary fibre provides energy for gut microbes, and they take their cut before we get our share. Livesey has calculated that all these factors reduce the energy derived from dietary fibre by 25 per cent
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“Cooking gives food energy,” says Wrangham. It alters the structure of the food at the molecular level, making it easier for our body to break it up and extract the nutrients.

In plants, for example, much of the energy from starch is stored as amylopectin, which is semi-crystalline, does not dissolve in water, and cannot be easily digested. Heat starchy foods with water, though, and the crystalline forms begin to melt. The starch granules absorb water, swell, and eventually burst. The amylopectin is shattered into short starch molecules called amylose, which are easily digested by the enzyme amylase.

It seems pretty obvious, just looking around, as you walk around in any city that people are much fatter, on average, than we were 20 years ago. And the data shows people were much larger (taller, but also fatter) 20 years ago than they were 100 years ago. And we know obesity causes many human health issues. The failure to address the obesity problem in the USA is another example of the failed “health care” system. Instead of a working health care system we just manage diseases that result for unhealthy living. We should be do better at providing information to people on healthy eating (including more accurate calorie counts as it concerns food we eat) and healthy lifestyle choices.

Moth Controlled Robot

Photo of moth controlled robot from Ryohei Kanzaki’s bio-machine page. The moth is on top of the ping pong ball in the middle of the robot.

Japanese scientists to build robot insects

Ryohei Kanzaki, a professor at Tokyo University’s Research Centre for Advanced Science and Technology, has studied insect brains for three decades and become a pioneer in the field of insect-machine hybrids.

His original and ultimate goal is to understand human brains and restore connections damaged by diseases and accidents – but to get there he has taken a very close look at insect “micro-brains”.
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Insects’ tiny brains can control complex aerobatics such as catching another bug while flying, proof that they are “an excellent bundle of software” finely honed by hundreds of millions of years of evolution, Prof Kanzaki said.
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In an example of ‘rewriting’ insect brain circuits, Prof Kanzaki’s team has succeeded in genetically modifying a male silkmoth so that it reacts to light instead of smell, or to the odour of a different kind of moth.

Such modifications could pave the way to creating a robo-bug which could in future sense illegal drugs several kilometres away, as well as landmines, people buried under rubble, or toxic gas, the professor said.

It is nice to be reminded of the cool research being done by professors all over the globe.

Pigeon Solves Box and Banana Problem

Laboratory footage showing a pigeon solving Wolfgang Kohler’s famous box-and-banana problem, which he studied with chimpanzees in the early 1900s. Depending on their previous experience, pigeons could solve this problem in a human-like fashion in as little as a minute. This pigeon has learned to push boxes and to climb, and it has been rewarded with grain for pecking at a small toy banana.

In this situation, the banana is out of reach and the box is not beneath it. At first the pigeon looks confused, then it begins pushing the box – sighting the toy banana as it pushes – and then stops pushing when the box is beneath the banana, then climbs and pecks. This and related studies were summarized in Dr. Epstein‘s 1996 book, Cognition, Creativity, & Behavior.

This is another example of interesting thoughtful bird behavior.

Robert Brooks on Robots

Rodney Brooks on advancing the use of robots in the world (speech from the Makir Fair).

Toyota Develops Thought-controlled Wheelchair

Toyota has developed a thought-controlled wheelchair (along with Japanese government research institute, RIKEN, and Genesis Research Institute). Honda has also developed a system that allows a person to control a robot through thoughts. Both companies continue to invest in innovation and science and engineering. The story of a bad economy and bad sales for a year or two is what you read in most newspapers. The story of why Toyota and Honda will be dominant companies 20 years from now is their superior management and focus on long term success instead of short term quarterly results.

The BSI-Toyota Collaboration Center, has succeeded in developing a system which utilizes one of the fastest technologies in the world, controlling a wheelchair using brain waves in as little as 125 milliseconds (one millisecond, or ms, is equal to 1/1000 seconds.

Plans are underway to utilize this technology in a wide range of applications centered on medicine and nursing care management. R&D under consideration includes increasing the number of commands given and developing more efficient dry electrodes. So far the research has centered on brain waves related to imaginary hand and foot control. However, through further measurement and analysis it is anticipated that this system may be applied to other types of brain waves generated by various mental states and emotions.

Algae Farm Aims to Turn Carbon Dioxide Into Fuel

Dow Chemical and Algenol Biofuels, a start-up company, are set to announce Monday that they will build a demonstration plant that, if successful, would use algae to turn carbon dioxide into ethanol as a vehicle fuel or an ingredient in plastics.
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“We give them the oxygen, we get very pure carbon dioxide, and the output is very cheap ethanol,” said Mr. Woods, who said the target price was $1 a gallon.

Algenol grows algae in “bioreactors,” troughs covered with flexible plastic and filled with saltwater. The water is saturated with carbon dioxide, to encourage growth of the algae. “It looks like a long hot dog balloon,” Mr. Woods said.
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The company has 40 bioreactors in Florida, and as part of the demonstration project plans 3,100 of them on a 24-acre site at Dow’s Freeport, Tex., site. Among the steps still being improved is the separation of the oxygen and water from the ethanol. The Georgia Institute of Technology will work on that process, as will Membrane Technology and Research, a company in Menlo Park, Calif. The National Renewable Energy Laboratory, an Energy Department lab, will study carbon dioxide sources and their impact on the algae samples.

Algenol and its partners are planning a demonstration plant that could produce 100,000 gallons a year. The company and its partners were spending more than $50 million, said Mr. Woods, but not all of that was going into the pilot plant.

Initial proof of science was generated by Dr. John Coleman at the University of Toronto between 1989 and 1999. Since then, the process has been refined to allow algae to tolerate high heat, high salinity, and the alcohol levels present in ethanol production. This is another example of the benefit of university research and investing in science and engineering innovation.

Saving the World with Science and Mushrooms

Entrepreneurial mycologist Paul Stamets studies mushrooms. The focus of Stamets’ research is the Northwest’s native fungal genome, mycelium, but along the way he has filed 22 patents for mushroom-related technologies, including pesticidal fungi that trick insects into eating them, and mushrooms that can break down the neurotoxins used in nerve gas.

The webcast really gets interesting at minute 9 or so (in my opinion) with 6 specific examples.

Related: Fun Fungi – Thinking Slime Moulds – Microbe Types

HHMI Expands Support of Postdoctoral Scientists

The Howard Hughes Medical Institute provides a huge amount of science and health care related funding. HHMI is expanding existing relationships to fund postdoc scientist fellows at with Jane Coffin Childs Memorial Fund, the Helen Hay Whitney Foundation, the Damon Runyon Cancer Research Foundation, and the Life Sciences Research Foundation. The funding should support 32 additional postdoc scientists. HHMI Expands Support of Postdoctoral Scientists

Fellows will be selected competitively by each organization. Each fellowship will have a three-year term. When the initiative is at full capacity, HHMI will be supporting 96 postdoctoral fellows at an anticipated annual cost of about $5 million. The program began in 2007 when HHMI announced it would fund up to 16 postdoctoral fellows in HHMI labs each year. There is no requirement that future fellows be appointed in HHMI labs.

Extremophile Hunter

NSF has begun publishing a new web magazine: Science Nation. The inaugural article is Extremophile Hunter

Astrobiologist Richard Hoover really goes to extremes to find living things that thrive where life would seem to be impossible–from the glaciers of the Alaskan Arctic to the ice sheets of Antarctica.
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“It may be that when we ultimately get a chance to bring back samples of ice from the polar caps of Mars, we might find biology that looks just like Earth life and it might be that it originated on Earth and was carried to Mars,” said Hoover. “Of course, if it can happen that way, it could have happened the other way. So we may never know the ultimate answer to how did life originate.”
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Some of the structures he has imaged from these meteorites are intriguing, bearing striking similarities to bacteria here on Earth. Could these be the fossilized remains of extraterrestial life?

“I am convinced that what I am finding in the carbonaceous meteorites are in many cases biological in nature, and I think they are indigenous and not terrestrial contaminants,” said Hoover.

It is a highly controversial interpretation. “We have for a long time thought that all life, as we know it, originated on Earth. And there isn’t any life anywhere else,” he said. “That’s an idea, it’s a hypothesis, it’s a totally unproven hypothesis.”

The First Web Server

photo of the first web server

Photo by sbisson from Geneva, Switzerland, November 2006 .

In a glass case at CERN is an unpreposessing little NeXT cube. It’s hard to believe that this little workstation changed the world, but it did. It’s Tim Berners Lee‘s original web server, the world’s first.

NeXT is the computer company Steve Jobs founded after he left Apple. Then he left NeXT to buy out Pixar. And then, of course, went back to Apple.