Category Archives: Science

Fishy Future?

Will seafood nets be empty? Grim outlook draws skeptics:

The researchers found that harvests of nearly 30 percent of commercial seafood species already have collapsed. Without major changes in fisheries management, they say, the trend will accelerate.

“It looks grim, and the projections into the future are even grimmer,” said Boris Worm, a marine biologist and a lead author in the peer-reviewed study, which was published today in the journal Science.

But other scientists question that forecast. “It’s just mind-boggling stupid,” said Ray Hilborn, a University of Washington professor of aquatic and fishery sciences.

The evidence seems pretty convincing overfishing has created serious problems and if unchecked those problems threaten to become even more serious. It also seems a stretch to claim those problems will be unchecked (that the checks will be less than they should be I think is a reasonable position). It seems to me the original stories talking about the end of fishing stocks in the next 40 years are alarmist to the point of being counterproductive.
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Programing Bacteria

Duke Packard Fellow to Examine Processing Speed of “Reprogrammed” Bacteria:

research into the development of synthetic gene circuits, carefully designed combinations of genes that can be “loaded” into bacteria or other cells, directing their activity in much the same way that a basic computer program directs a computer. Such re-programmed bacteria might eventually serve in a wide variety of applications, including biocomputing, medical treatments, and environmental cleanup
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The research now, however, is in its very early stages, You said. So far, E. coli bacteria have been programmed to grow in numbers until a certain population size is reached. The bacteria then kill themselves off, growing again only after their numbers dwindle sufficiently.

The relatively simple program takes advantage of bacteria’s ability to communicate with one another, a process known as “quorum sensing,” and essential genetic pathways that control cell death.

Medical Buckyballs

Secret’s in the stuffing – Researchers fill ‘buckyballs’ with metals in hopes they’ll have medical applications

Virginia Tech has been stuffing hollow buckyballs, or fullerenes, with metals in hopes they could someday be used as contrast agents for imaging or tracing cancer cells.

Nobel laureate and co-discoverer Harold Kroto of Florida State University, who worked out the structural rule that the buckyegg violates, learned of Virginia Tech’s pursuit of buckyballs for pharmaceutical and medical applications during a visit to Blacksburg this month.

“It’s very exciting,” he said, joking that he’d been about ready to give back his Nobel because no one had found humanitarian uses for buckyballs until now.

The buckyegg is the latest from Virginia Tech, where in 1999 Harry Dorn and a team of chemists created the first buckyballs made with a shell of 80 carbon atoms and three metal atoms stuffed inside.

Energy Efficiency of Digestion

Why is Fecal Matter Brown?

The complex digestion process ensures that almost no useful energy goes unused. The average bowel movement is three parts water to one part solid matter. Bacteria make up 30 percent of the solid stuff. The same goes for indigestible foods like cellulose and extra fiber. The remaining 40 percent contains various inorganic wastes, fats and used-up body substances like red blood cells

Scientists Examine 100 Trillion Microbes in Human Feces:

Aiding the large intestine in this task are trillions of microbes that reside in the gut, where they help digest foods we would otherwise have to avoid. In this way the bugs contribute to our overall health.

Some of these tiny settlers are with us from birth, imparted from our mothers, while others gradually colonize our bodies as we grow. This microbial community is as diverse as any found in Earth’s seas or soils, numbering up to 100 trillion individuals and representing more than 1,000 different species.

SMART Fellowships

The Science, Mathematics, And Research for Transformation Defense Scholarship for Service Program (SMART) is administrated by ASEE. As I have stated before – while I work for ASEE this blog is my own and is not associated with ASEE.

Program highlights include:

Starting salary/stipend ranging from $22,500 for undergraduates to $38,000 for doctoral students
Full tuition and related education fees and a book allowance of $1,000
Paid summer internships
Career opportunities after graduation

Read more about the program and apply online – the deadline is 5 February 2007. Article on the SMART program from ASEE’s magazine: PRISM.

The deadline from the NSF Graduate Research Fellowship is as early as tomorrow for some applications and as late as November 13th for others.

Educating Scientists and Engineers

Business Week has an articles discussing what business would like to see from graduates, Biotech’s Beef:

The problem is a disconnect between what universities are teaching and what biotech wants. “The focus of academia is getting basic and theoretical knowledge in place,”
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There are several weaknesses. First, recent grads lack the technical knowledge to carry out applied research in areas that straddle engineering, math, and computers. Second, job candidates have little awareness of what the Food & Drug Administration is looking for when it considers whether or not to approve a drug. Recent grads simply aren’t familiar with issues such as quality control and regulatory affairs.

This general idea is not new. But, as always (and probably more so if the nature of what is needed is changing faster today than in the past) the changing environment does require universities (and students, at least those that want to work in industry) to adapt.

But with H-1B quotas filling up earlier every year, Invitrogen has chosen to do more drug development in Japan, China, and India. It may also open facilities in Korea and Singapore, says Rodney Moses, Invitrogen’s vice-president of talent acquisition. Compensation in China and India is lower than in the U.S., but that’s not what motivates the move offshore, says Moses. “If the talent is located in Singapore, it’s just easier for us to go there.”

U.S. colleges take the problem seriously. State university systems in California, Wisconsin, and elsewhere are adding more industry-oriented classes.

New Visualization of the Periodic Table

New Visualization of the Periodic Table from the New York Times.

Antibiotic Research

anti-microbial ‘grammar’ posits new language of healing

“In the last 40 years, there have been only two new classes of antibiotic drugs discovered and brought to the market,” said graduate student Christopher Loose, lead author of a paper on the work that appears in the Oct. 19 issue of Nature. “There is an incredible need to come up with new medicines.”
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focusing their attention on antimicrobial peptides, or short strings of amino acids. Such peptides are naturally found in multicellular organisms, where they play a role in defense against infectious bacteria.

See previous post on the paucity of new antibiotic discoveries

More Great Webcasts: Nanotech and more

ScienceLive video archive from Cambridge University Science Productions. Videos include:

Viruses as nanomachines by Peter Stockley
Powering nanodevices with biomolecular motors by Amir Khan
Ice Cream, Chocolate, and Einstein by Chris Clarke
Communicating Science by Brian Trench and David Dickson
So many experiments, live in the studio! by Paul McCrory

Great stuff, another example of universities providing open access content 🙂

Complete Work of Charles Darwin Online

Complete Work of Charles Darwin Online – The University of Cambridge has done a much better job of use the web effectively than some others: Classic Botanical Illustrations Presented Poorly. The site includes 50,000 pages and 40,000 images (publications and handwritten manuscripts), including, of course, Origin of Species. Fantastic stuff.