Category Archives: Science

Wonderful Views of Life Using Micro-photography

The Olympus BioScapes 2011 Winners Gallery is full of great photos and videos of micro bioscapes.

Floschularia Ringerns Rotifer feeding by Charles Crebs

Winning photo by Mr. Charles Krebs, Issaquah, Washington, USA
Specimen: Rotifer Floscularia ringens feeding. Its rapidly beating cilia (hair-like structures) bring water containing food to the rotifer
Technique: Differential interference contrast microscopy

The photo shows the microscopic animal’s self-made reddish tube-shaped home, with a building block in the process of being formed inside the rotifer’s body.

Scientists Singing About Science

Fun video with scientists singing about science.

More scientists singing science songs: Friday Fun, Large Hadron Rap – Cambrian Explosion Song – The Sun is a Miasma of Incandescent Plasma – Protein Synthesis: 1971 Video

An Apple a Day is Good Advice

Apples really are healthy food. They provide fiber and nutrients without a large amount of calories. Including them in your diet can contribute to a healthy lifestyle.

How apples can make you skinnier & 4 more health benefits of apples

Packing in quite a bit of soluble fiber (4 grams per medium apple) for a modest amount of calories (95) makes apples a filling, sweet snack. Plus, a medium apple counts as 1 cup of fruit, so after eating one you’re well on your way to meeting your daily fruit quota (around 2 cups for adults on a 2,000-calorie diet). They also are a good source of immune-boosting vitamin C (providing 14% of the Daily Value).
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a survey of eating and health habits, found that people who had eaten apples in any form over the past day were 27 percent less likely to have symptoms of metabolic syndrome than those who didn’t. The apple eaters also had lower levels of C-reactive protein, a marker of inflammation whose presence in the blood suggests an increased risk for heart disease and diabetes.

“Our study suggests that ursolic acid increases skeletal muscle and brown fat leading to increased calorie burning, which in turn protects against diet-induced obesity, pre-diabetes and fatty liver disease,” Christopher Adams, M.D., Ph.D., UI associate professor of internal medicine at the University of Iowa.

Until quite recently, researchers believed that only infants had brown fat, which then disappeared during childhood. However, improved imaging techniques have shown that adults do retain a very small amount of the substance mostly in the neck and between the shoulder blades. Some studies have linked increased levels of brown fat with lower levels of obesity and healthier levels of blood sugar and blood lipid, leading to the suggestion that brown fat may be helpful in preventing obesity and diabetes.

Using Robots to Collect Data on our Oceans

Interesting idea to use self propelled robots to provide data on the oceans. They use no fuel to move, they use wave energy. They also have solar panels on the top. The wave gliders can travel to a distant area, collect data, and return to base. One of the big problems with convention methods of collecting data on the oceans is the large costs of placing the buoys (and the cost of servicing them).

One Scientists 20 Year Effort to Defeat Dengue Fever

As I have said many times scientific breakthroughs often follow many years of effort. Here is a great example of a scientist putting in great work for years and it looks like it is about to payoff for hundreds of millions of people.

A Scientist’s 20-Year Quest To Defeat Dengue Fever

Now as I said, Scott’s been pushing this idea of using Wolbachia to control dengue for decades, for a most of that time without any success. I asked Scott what it takes to stick with something for that long.

“I think being obsessive,” he replied. “Being maybe a little ill in that regard. And it’s just that I seem to have focused my obsession onto Wolbachia instead of on to postage stamps or model trains.”

And even though his obsession has brought him to the point where he’s shown he can get his Wolbachia-infected mosquitoes to spread in the wild, that’s not the success he’s ultimately after. “Success for me is having a significant impact on dengue disease in communities,” he says.

To do that, he’ll have to release his mosquitoes in a place where there’s a lot of dengue, and then see if that brings down the number of cases of the disease in humans. Those studies are being planned now.

The stakes are high. By some estimates, more than a billion people around the world are at risk for getting dengue. Even if it doesn’t kill you, I’m told a case of dengue can make you feel so bad, wish you were dead.
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But Scott says it’s not yet time to celebrate.

“We’ve got some good preliminary data, and we’re on the path. And it’s looking good. But you know I am a realist. It could fall over at any day,” says Scott.

Prostate Cancer Drug so Effective Trial Stopped to Give Drug to All Participants

Prostate cancer drug so effective trial stopped by Victoria Colliver

The hormone treatment, Johnson & Johnson’s Zytiga, when added to a standard steroid therapy doubled the time it takes for the disease to progress in patients treated with the standard therapy alone, said the lead researcher, Dr. Charles Ryan, associate professor of clinical medicine at the UCSF Helen Diller Family Comprehensive Cancer Center.

The U.S. Food and Drug Administration last year approved Zytiga, also known as abiraterone, for use in men whose prostate cancer had spread to other parts of their body and had already been treated with chemotherapy.
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This trial focused on patients whose cancer had metastasized, may have been treated with other hormone therapies but had not yet gone through chemotherapy.
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Prostate cancer, the second most common form of cancer in males after only lung cancer, is diagnosed in about 200,000 men in the United States each year. And while it is generally treatable, the disease kills nearly 30,000 men a year.

Because their disease is often slow-growing, about a third of patients diagnosed with prostate cancer won’t be treated. Another third will undergo successful treatment, which could include surgery, various hormone therapies or chemotherapy.

Still, a third of patients will have recurrent or aggressive disease that may have been caught too late. Ryan said men tend to die when the cancer spreads outside the prostate, mostly to bone, and the patient becomes resistant to hormonal therapy. The cancer cells rely on testosterone to exist, so typically doctors treat patients with testosterone-blocking hormone therapy.

But patients become resistant when the cancer cells develop the ability to make their own hormone and learn to survive even in the face of the testosterone-blocking drugs, giving the disease the ability to progress, Ryan said.

Zytiga is the first FDA-approved drug that can go inside the cancer cell and block it from making its own testosterone.

The trial involved 1,088 men who were being treated by 151 cancer centers in 12 countries. Each was given a low dose of the steroid prednisone, which works to combat the cancer

This is very good news. There is lots of positive news over the years. Often it seems to come to nothing years later. Promising drugs in the lab turn out to be far less promising in clinical trail. But very successful clinical trials are very good news. Even this kind of news though really should be confirmed by larger scale success, but this is a very good start.

Good Chemistry: A Love Song for Ionic Bonds

Song and video by 10th grade student, Eli Cirino, for extra credit in his chemistry class.

An ionic bond is a type of chemical bond formed through an electrostatic attraction between two oppositely charged ions. Ionic bonds are formed between a cation, which is usually a metal, and an anion, which is usually a nonmetal.

An ionic bond is considered a bond where the ionic character is greater than the covalent character (ionic bonds cannot exist on their own, they must have a covalent bond present also).

Scientific Inquiry Process Finds More Evidence Supporting Einstein’s Theory

As scientists have been able to see farther and deeper into the universe, the laws that govern its expansion have been revealed to be under the influence of an unexplained force.

In a paper on the arXiv, Astrophysical Tests of Modified Gravity: Constraints from Distance Indicators in the Nearby Universe, are a vindication of Einstein’s theory of gravity. Having survived several decades of tests in the solar system, it has passed this new test in galaxies beyond our own as well.

In 1998, astrophysicists made an observation that turned gravity on its ear: the universe’s rate of expansion is speeding up. If gravity acts the same everywhere, stars and galaxies propelled outward by the Big Bang should continuously slow down, like objects thrown from an explosion do here on Earth.

This observation used distant supernovae to show that the expansion of the universe was speeding up rather than slowing down. This indicated that something was missing from physicists’ understanding of how the universe responds to gravity, which is described by Einstein’s theory of general relativity. Two branches of theories have sprung up, each trying to fill its gaps in a different way.

One branch — dark energy — suggests that the vacuum of space has an energy associated with it and that energy causes the observed acceleration. The other falls under the umbrella of “scalar-tensor” gravity theories, which effectively posits a fifth force (beyond gravity, electromagnetism and the strong and weak nuclear forces) that alters gravity on cosmologically large scales.

“These two possibilities are both radical in their own way,” University of Pennsylvania astrophysicist Bhuvnesh Jain said. “One is saying that general relativity is correct, but we have this strange new form of energy. The other is saying we don’t have a new form of energy, but gravity is not described by general relativity everywhere.”

Jain’s research is focused on the latter possibility; he is attempting to characterize the properties of this fifth force that disrupts the predictions general relativity makes outside our own galaxy, on cosmic length scales. Jain’s recent breakthrough came about when he and his colleagues realized they could use the troves of data on a special property of a common type of star as an exquisite test of gravity.

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Modeling Weight Loss Over the Long Term

Researchers at the National Institutes of Health have created a mathematical model of what happens when people of varying weights, diets and exercise habits try to change their weight. The findings challenge the commonly held belief that eating 3,500 fewer calories, or burning them off exercising, will result in a pound of weight loss.

Instead, the researchers’ computer simulations indicate that this assumption overestimates weight loss because it fails to account for how metabolism changes. The computer simulations show how these metabolic changes can significantly differ among people.

However, the computer simulation of metabolism is meant as a research tool and not as a weight-loss guide for the public. The computer program can run simulations for changes in calories or exercise that would never be recommended for healthy weight loss. The researchers hope to use the knowledge gained from developing the model and from clinical trials in people to refine the tool for everyone.

“This research helps us understand why one person may lose weight faster or slower than another, even when they eat the same diet and do the same exercise,” said Kevin Hall, Ph.D., an obesity researcher and physicist at the NIH’s National Institute of Diabetes and Digestive and Kidney Diseases. “Our computer simulations can then be used to help design personalized weight management programs to address individual needs and goals.”

The online simulation tool based on the model enables researchers to accurately predict how body weight will change and how long it will likely take to reach weight goals based on a starting weight and estimated physical activity. The tool simulates how factors such as diet and exercise can alter metabolism over time and thereby lead to changes of weight and body fat.

The team found that people’s bodies adapt slowly to changes in dietary intake. They also found heavier people can expect greater weight change with the same change in diet, though reaching a stable body weight will take them longer than people with less fat.

The model also points to a potential simplified method to approximate weight loss in an average overweight person. An adult who has a body mass index (a measure of a person’s weight in relation to his or her height) between 25 and 29.9 is considered overweight. One example: For every pound you want to lose, permanently cut 10 calories from your current intake per day. At that rate, it will take about one year to achieve half of the total weight loss, and almost all of the weight loss will have occurred by three years. This calculation shows how long it takes to achieve a weight-loss goal for a single permanent change of diet or exercise.

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Video of Young Richard Feynman Talking About Scientific Thinking

The enjoyable video above shows a young Richard Feynman discussing how scientific thinking can advance our understanding of the world.