Category Archives: Science

Cuts for British Science

Cuts mark ‘sad day for British science’

Britain’s physics community is reeling from a “disastrous” day of funding cuts that will force scientists to withdraw from major research facilities and see PhD studentships fall by a quarter. Space missions and projects across astronomy, nuclear and particle physics are being cancelled to save at least £115m, the Science and Technology Facilities Council (STFC) said today.

Fellowships and student grants for PhD projects will be cut by 25% from next year. The announcement has appalled senior physicists who warn the cuts threaten Britain’s future as a leading player in science.

In February, Gordon Brown delivered his first speech on science in Oxford and stated: “The downturn is no time to slow down our investment in science but to build more vigorously for the future.”

Politicians like to talk about funding science investment. And they do so to some extent. However, they are more reluctant to actually spend money than to talk about the wonders of science. Several countries in Asia are not just talking, they continue to invest, large amounts of money. The USA seems to be willing to put some money (not the kind of funds paid to protect bankers bonuses but significant amounts). Still the amounts the USA is investing is, I believe, falling as a percentage of global investment.

Related: posts on funding investments in scienceBritain’s Doctors of InnovationEconomic Strength Through Technology LeadershipScience and Engineering in Global EconomicsScience and Engineering Workforce IndicatorsThe value of investing in science and engineeringSaving FermilabNanotechnology Investment as Strategic National Economic Policy

Unless We Take Decisive Action, Climate Change Will Ravage Our Planet

Lake McDonald, Glacier National Park photo by John Hunterphoto by John Hunter at Glacier National Park.

Tomorrow 56 newspapers, in 45 countries, are taking the unprecedented step of publishing the same editorial. The editorial will appear in 20 languages, as the United Nations Climate Change Conference is set to begin in Copenhagen.

Unless we combine to take decisive action, climate change will ravage our planet, and with it our prosperity and security. The dangers have been becoming apparent for a generation. Now the facts have started to speak: 11 of the past 14 years have been the warmest on record, the Arctic ice-cap is melting and last year’s inflamed oil and food prices provide a foretaste of future havoc. In scientific journals the question is no longer whether humans are to blame, but how little time we have got left to limit the damage. Yet so far the world’s response has been feeble and half-hearted.

Climate change has been caused over centuries, has consequences that will endure for all time and our prospects of taming it will be determined in the next 14 days. We call on the representatives of the 192 countries gathered in Copenhagen not to hesitate, not to fall into dispute, not to blame each other but to seize opportunity from the greatest modern failure of politics. This should not be a fight between the rich world and the poor world, or between east and west. Climate change affects everyone, and must be solved by everyone.

The science is complex but the facts are clear. The world needs to take steps to limit temperature rises to 2C, an aim that will require global emissions to peak and begin falling within the next 5-10 years.

Few believe that Copenhagen can any longer produce a fully polished treaty; real progress towards one could only begin with the arrival of President Obama in the White House and the reversal of years of US obstructionism. Even now the world finds itself at the mercy of American domestic politics, for the president cannot fully commit to the action required until the US Congress has done so.

the rich world is responsible for most of the accumulated carbon in the atmosphere – three-quarters of all carbon dioxide emitted since 1850. It must now take a lead, and every developed country must commit to deep cuts which will reduce their emissions within a decade to very substantially less than their 1990 level.

The transformation will be costly, but many times less than the bill for bailing out global finance — and far less costly than the consequences of doing nothing.

Many of us, particularly in the developed world, will have to change our lifestyles. The era of flights that cost less than the taxi ride to the airport is drawing to a close. We will have to shop, eat and travel more intelligently. We will have to pay more for our energy, and use less of it.

Kicking our carbon habit within a few short decades will require a feat of engineering and innovation to match anything in our history. But whereas putting a man on the moon or splitting the atom were born of conflict and competition, the coming carbon race must be driven by a collaborative effort to achieve collective salvation.

The politicians in Copenhagen have the power to shape history’s judgment on this generation: one that saw a challenge and rose to it, or one so stupid that we saw calamity coming but did nothing to avert it. We implore them to make the right choice.

Most of the newspapers have taken the unusual step of featuring the editorial on their front page. Even with the overwhelming evidence and tremendous consequences I don’t expect politicians to make the right decisions. We know full well what the choices are. We just decide to avoid the unpleasant choices. To bad so many that don’t get to choose are going to suffer. The politicians will be weak. They will play to those that pay them money. They will delay taking important steps now. We have chosen to elect non-leaders for quite some time. We can’t really expect them to act with courage, vision, wisdom and leadership given who we elect. The politicians are responsible for their failing but we are more responsible for electing them. Some politicians, even now, do possess fine qualities but not nearly enough. Maybe I will be proven wrong, but I doubt it.

Related: What’s Up With the Weather?Arctic System on Trajectory to New, Seasonally Ice-Free StateScientists Denounce Global Warming Report EditsDeforestation and Global WarmingMIT’s Energy ‘Manhattan Project’Global Installed Wind Power Now Over 1.5% of Global Electricity DemandBigger Impact: 15 to 18 mpg or 50 to 100 mpg?Solar Thermal in Desert, to Beat Coal by 202076 Nobel Laureates in Science Endorse Obama

Statistics Insights for Scientists and Engineers

My father was a engineer and statistician. Along with George Box and Stu Hunter (no relation) they wrote Statistics for Experimenters (one of the potential titles had been Statistics for Engineers). They had an interest in bringing applied statistics to the work of scientists and engineers and I have that interest also. To me the key trait for applied statistics is to help experimenters learn quickly: it is an aid in the discovery process. It should not be a passive tool for analysis (which is how people often think of statistics).

José Ramírez studied applied and industrial statistics at the University of Wisconsin – Madison with my father and George Box. And now has a book and blog on taking statistics to engineers and scientists

The book is primarily written for engineers and scientists who need to use statistics and JMP to make sense of data and make sound decisions based on their analyses. This includes, for example, people working in semiconductor, automotive, chemical and aerospace industries. Other professionals in these industries who will find it valuable include quality engineers, reliability engineers, Six Sigma Black Belts and statisticians.

For those who want a reference for how to solve common problems using statistics and JMP, we walk through different case studies using a seven-step problem-solving framework, with heavy emphasis on the problem setup, interpretation, and translation of the results in the context of the problem.

For those who want to learn more about the statistical techniques and concepts, we provide a practical overview of the underpinnings and provide appropriate references. Finally, for those who want to learn how to benefit from the power of JMP, we have loaded the book with many step-by-step instructions and tips and tricks.

Related: Highlights from George Box Speech at JMP conference Nov 2009Controlled Experiments for Software SolutionsMistakes in Experimental Design and InterpretationFlorence Nightingale: The passionate statistician

Stat Insights is a blog by José and Brenda Ramírez.

Analyzing and Interpreting Continuous Data Using JMP by José and Brenda Ramírez. view chapter 1 online.

[We] have focused on making statistics both accessible and effective in helping to solve common problems found in an industrial setting. Statistical techniques are introduced not as a collection of formulas to be followed, but as a catalyst to enhance and speed up the engineering and scientific problem-solving process. Each chapter uses a 7-step problem-solving framework to make sure that the right problem is being solved with an appropriate selection of tools.

Zubbles – Get Your Colored Bubbles

photo of blue bubblephoto of blue colored bubble.

I first posted on this in 2005: Colored Bubbles. Now you can order your own via Zubbles. Colored Bubbles Have Landed (and Popped and Vanished)

Having solved the colored bubble dilemma, we spent most of 2006 trying to refine our dyes and the manufacturing process. We had invented several completely new dyes and a few derivatives of existing dyes. But the manufacturing process was long, tedious and expensive. It took three days just to make a few grams of each dye. It quickly became apparent that we needed to radically streamline the production process in order to have a viable product.

The complexities of the chemistry resembled a pharmaceutical more than a toy. So I enlisted the help of Gary Willingham, and the Belgium development team, at Fisher Scientific. Fisher is a pharmaceutical chemical manufacturer with the equipment and expertise needed to manufacture tons of our dyes.

Due to the complexities of the chemistry, Jamm decided to stay close to the production process and manufacture Zubbles in the US. The first bottles rolled off the line this week. Jamm presented me with the very first case of Zubbles. And it was a very strange feeling to finally hold the product in my hand—15 years after I mixed my first batch of dishwashing detergent and food coloring.

Being an entrepreneur is a challenge any time. When your product requires complex science and engineering that adds additional challenges. It is great to see this product is now available.

Related: Making Magnificent Mirrors with Math1979 “iPod-like” Music PlayerThe Glove – Engineering Coolnessscience and engineering gadgets and giftsBuild Your Own Tabletop Interactive Multi-touch ComputerAwesome Cat Cam

Protein Synthesis: 1971 Video

The above webcast shows protein synthesis, from a 1971 Stanford University video with Paul Berg (Nobel Laureate – 1980 Nobel Prize for Chemistry and National Medal of Science in 1983). The film does not exactly present the traditional scientist stereotype. It does pretty much present the typical California 1970’s hippie stereotype though.

Related: Friday Fun – CERN VersionRoger Tsien Lecture On Green Florescent Protein

Feynman “is a second Dirac, only this time human”

Oppenheimer recommendation of Feynman, page 1

Great quotes from Oppenheimer’s recommendation of Richard Feynman

“He is by all odds the most brilliant young physicist here, and everyone knows this. He is a man of thoroughly engaging character and personality, extremely clear, extremely normal in all respects, and an excellent teacher with a warm feeling for physics in all its aspects. He has the best possible relations both with the theoretical people of whom he is one, and with the experimental people with whom he works in very close harmony.”

Bethe has said that he would rather lose any two other men than Feynman from this present job, and Wigner said, ‘He is a second Dirac, only this time human.”

Oppenheimer recommendation of Feynman, page 2

Images of letter from Oppenheimer to the University of California – Berkeley Recommending Richard Feynman for a position, November 4, 1943 (from Big Science at Berkeley).

via: He is a second Dirac, only this time human.

Related: Vega Science Lectures: Feynman and MoreThe Feynman Lectures on Physics by Richard P. Feynman and Robert B. Leighton and Matthew Sands – posts on physics

Ants Counting Their Step

Ants That Count!

Most ants get around by leaving smell trails on the forest floor that show other ants how to get home or to food. They squeeze the glands that cover their bodies; those glands release a scent, and the scents in combination create trails the other ants can follow.

That works in the forest, but it doesn’t work in a desert. Deserts are sandy and when the wind blows, smells scatter.

It’s already known that ants use celestial clues to establish the general direction home, but how do they know exactly the number of steps to take that will lead them right to the entrance of their nest?

Wolf and Whittlinger trained a bunch of ants to walk across a patch of desert to some food. When the ants began eating, the scientists trapped them and divided them into three groups. They left the first group alone. With the second group, they used superglue to attach pre-cut pig bristles to each of their six legs, essentially putting them on stilts.

The regular ants walked right to the nest and went inside. The ants on stilts walked right past the nest, stopped and looked around for their home…

I posted about this back in 2006: Ants on Stilts for Science, but the webcast by NPR is worth a new post.

Related: E.O. Wilson: Lord of the AntsHuge Ant Nestposts showing the scientific method of learning in action

Disrupting Bacterial Communication to Thwart Them

Interrupting Bacterial Chatter to Thwart Infection

To measure their own numbers, bacteria produce, release, and detect chemical signals called autoinducers. As a population of bacteria grows, it releases more autoinducer into its environment. When individuals detect that a threshold level of autoinducer is present, they change their behavior – by releasing a toxin, for example.

Bassler and her colleagues disrupted these lines of communication by interfering with molecules called acyl-homoserine lactone (AHL) autoinducers, which drive quorum sensing among a kind of bacteria known as Gram-negative bacteria. Gram-negative bacteria include Pseudomonas, E. coli and Salmonella, and other disease-causing microbes. In the study, the team focused on Chromobacterium violaceum, which rarely infects human, but can be lethal to other organisms. C. violaceum lends itself to studies of quorum sensing because it produces a readily detected, bright purple dye when it detects that its population has reached a critical mass.

The experiment shows that interfering with quorum sensing may provide an alternative to traditional antibiotics, Bassler says, and circumvent the problem of resistance that antibiotics foster by killing off susceptible bacteria but allowing resistant ones to survive and propagate.

Related: Bacteria Communicate Using a Chemical Language (quorum sensing)Disrupting Bacteria Communication (2007)Electrolyzed Water Replacing Toxic Cleaning SubstancesGram-negative Bacteria Defy Drug Solutions

President Obama Speaks on Getting Students Excited About Science and Engineering

The President announces the “Educate to Innovate” initiative, a campaign to get students excited about pursuing careers in science, technology, engineering and mathematics. Quotes from President Obama from his speech – (see webcast above):

“As President, I believe that robotics can inspire young people to pursue science and engineering.”

“Now the hard truth is that for decades we’ve been losing ground. One assessment shows American 15-year-olds now rank 21st in science and 25th in math when compared to their peers around the world.”

“And today, I’m announcing that we’re going to have an annual science fair at the White House with the winners of national competitions in science and technology. If you win the NCAA championship, you come to the White House. Well, if you’re a young person and you’ve produced the best experiment or design, the best hardware or software, you ought to be recognized for that achievement, too. Scientists and engineers ought to stand side by side with athletes and entertainers as role models, and here at the White House we’re going to lead by example. We’re going to show young people how cool science can be.”

“improving education in math and science is about producing engineers and researchers and scientists and innovators who are going to help transform our economy and our lives for the better.”

Related: 2008 Intel Science Talent SearchReport on K-12 Science Education in USAFun k-12 Science and Engineering LearningScience Education in the 21st CenturyHigh School Inventor Teams @ MITEngineering Education Program for k-1276 Nobel Laureates in Science Endorse ObamaLego Learning