Category Archives: Science

Virus Engineered To Kill Deadly Brain Tumors

Yale Lab Engineers Virus That Can Kill Deadly Brain Tumors

A laboratory-engineered virus that can find its way through the vascular system and kill deadly brain tumors has been developed by Yale School of Medicine researchers, it was reported this week in the Journal of Neuroscience.

Each year 200,000 people in the United States are diagnosed with a brain tumor, and metastatic tumors and glioblastomas make up a large part of these tumors. There currently is no cure for these types of tumors, and they generally result in death within months.
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“Three days after inoculation, the tumors were completely or almost completely infected with the virus and the tumor cells were dying or dead,” van den Pol said. “We were able to target different types of cancer cells. Within the same time frame, normal mouse brain cells or normal human brain cells transplanted into mice were spared. This underlines the virus’ potential therapeutic value against multiple types of brain cancers.”

Pretty cool. Too bad these press releases never quite live up to the initial promise. Still this one is very cool, if it can succeed in helping even a small percentage of people it will be a great breakthrough. It is also just cool – using a virus to kill tumors – how cool is that?

Scientists Search for Clues To Bee Mystery

Honey Bees Give Clues on Virus Spread by Carl Zimmer

Now, as farmers wait anxiously to see if the honeybees will suffer again this spring, the true cause of CCD remains murky. Skeptics have raised many reasons to doubt that Australian viruses are to blame. In Australia, bees that get Israeli acute paralytic virus don’t get sick, and the country has had no reports of CCD. And in places where honeybee colonies are collapsing — Greece, Poland, Spain — there are no imported Australian bees. These are not the sort of patterns you’d expect, the skeptics say, if Australian viruses were killing American bees.
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Whether scientists look inside a honeybee or look at the entire biosphere, nature is proving to be awesomely intricate. In the oceans and the soil, metagenomics is revealing millions of different kinds of microbes, with an almost inconceivable diversity of viruses shuttling between them, carrying genes from host to host. But we have almost no idea how these menageries work together, either in the biosphere or inside a host like a honeybee — or a human. Many of the microbes that metagenomics is revealing are entirely new to science. As genetic databases fill with DNA sequences from millions of new species, our scientific wisdom lags far behind.

How true. Watching as scientists try to work out what is going on with Colony Collapse Disorder is a great lesson in how scientists search for answers. As I stated earlier much of science is not about simple obvious truths but a search through confusing signs to try and determine what is going on. Answering why, is not always so easy as it appears when someone has already found the answer and posted it online.

Electron Filmed for the First Time

Now it is possible to see a movie of an electron. The movie shows how an electron rides on a light wave after just having been pulled away from an atom. This is the first time an electron has ever been filmed. Previously it has been impossible to photograph electrons since their extremely high velocities have produced blurry pictures. In order to capture these rapid events, extremely short flashes of light are necessary, but such flashes were not previously available.

With the use of a newly developed technology for generating short pulses from intense laser light, so-called attosecond pulses, scientists at the Lund University Faculty of Engineering in Sweden have managed to capture the electron motion for the first time. “It takes about 150 attoseconds for an electron to circle the nucleus of an atom. An attosecond is 10-18 seconds long, or, expressed in another way: an attosecond is related to a second as a second is related to the age of the universe,” says Johan Mauritsson, an assistant professor in atomic physics at the Faculty of Engineering, Lund University.

Scientists also hope to find out more about what happens with the rest of the atom when an inner electron leaves it, for instance how and when the other electrons fill in the gap that is created. “What we are doing is pure basic research. If there happen to be future applications, they will have to be seen as a bonus,” adds Johan Mauritsson. The length of the film corresponds to a single oscillation of the light, but the speed has then been ratcheted down considerably so that we can watch it. The filmed sequence shows the energy distribution of the electron and is therefore not a film in the usual sense.

Photo: Experimental results obtained in helium at an intensity of 1:2 x 1013 W=c/m2 are shown. The results are
distinctively different from those taken in argon (Fig. 1).With this higher intensity, more momentum is transferred to the electrons, and in combination with the lower initial energy, some electrons return to the atomic potential for further interaction. In the first panel, we compare the experimental results (right) with theoretical calculations (left) obtained for the same conditions.
Continue reading →

Thailand’s Contribution to the ISEF

Intel to send 5 to US

Intel Microelectronics (Thailand) Ltd is sponsoring five young Thai students to participate in the 59th Intel International Science and Engineering Fair (Intel ISEF) in Atlanta, Georgia
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Two of the individual entries are a musical instrument sound analysis and recognition system, which won the first prize in the computer science category, and was developed by Boonyarit Somrealvongkul, and a method of measuring a curved path’s radius with a modified car, which took first prize in the engineering category and was developed by Ronnapee Chaichaowarat.

The third project is a team entry, “New Plywood Products”, the first prize winner in the environmental science category, developed by Pheemadej Prasitwarawej, Tanavorakit Bangkeaw and Manapas Hararak, from Montfort College, Chiang Mai.

Over 1,500 of the brightest young scientists from around the world attend the fair every year, where they share ideas, showcase cutting-edge science projects and compete for more than $3 million (94.5 million baht) in awards and scholarships.

Leafhopper Feeding a Gecko

Some of this stuff is just fun. The leafhopper feeds on the sap of the tree. And the Gecko will stop by and wait to be fed. The narrator explains that scientists have not determined why this happens, perhaps the Gecko keeps aware predators? That seems somewhat flimsy as a guess to me but what do I know. The narrator does say that the sweet honeydew is what remains from the sap once the leafhopper has extracted the protein.

High School Students in USA, China and India

2 million minutes is a documentary film looking at education in USA, China and India. The producers offer a blog, What Should America Do?, which is interesting.

this blog offers deeper insights into education in China, India and the United States, and the challenge America faces. Now you can join a dialog about what governments, communities and families should and are doing to best prepare US students for satisfying careers in the 21st century.

U.S. Students Can’t Compete in High-Tech World

The film follows two students from Carmel High School in Indianapolis, as well as two students from India and two from China. The premise is that they all have roughly 2 million minutes in high school to build their intellectual foundation and prepare for college and a career.

Twenty months in the making, “2 Million Minutes” highlights the pressures and priorities of these students and their families. Ultimately, it provides insight into the changing nature of competition in a technology-based global economy.
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“As a high-tech entrepreneur and venture capitalist for the past 25 years,” Compton said,” I can tell you the people who have reaped the greatest economic rewards in the past two decades have been those with the most rigorous and thorough understanding of technology — and thus a solid foundation in math and science — and who have an ability to solve problems and possess entrepreneurial skill.”

I strongly agree with the economic benefits from strong science and engineering education and the personal benefit of science and technology expertise (one small example: S&P 500 CEOs – Again Engineering Graduates Lead).

See some of our previous posts on similar matters: The Importance of Science Education – USA Teens 29th in Science – Scientific Illiteracy – Fun k-12 Science and Engineering Learning – Diplomacy and Science Excellence – Lego Learning

The Economic Consequences of Investing in Science Education

My comments on: National Association of High School Principals Takes Exception to Two Million Minutes

Thanks for saying what has to be said. I have talked on similar themes on my blog for awhile now. The USA is definitely losing its relative position as the clear leader for science and engineering excellence.

The debate now whether we are willing to invest more today to slow the decline or whether we are willing to risk the economic future where our centers of science and engineering excellence are eclipsed quickly.

There is a long lag time that has allowed us to coast for the last 30 or so years. The reality is that most Americans suffer under the illusion we are in the same position we were in 1970’s. We are not and it is obvious to me that the economic impacts are starting to have dramatic effects now and it will only increase.

It might be more pleasant to explain why the USA is fine the way it is but that is a mistake. For more on my thoughts see two categories of the Curious Cat Science and Engineering Blog: Economics and primary science education and 2 posts: The Future is Engineering and the Political Impact of Global Technology Excellence.

One Reason Bacteria Gain Tolerance So Quickly

I recently read Good Gems, Bad Germs as part of my effort to learn more about bacteria, viruses, how are bodies work, cells, microbiology etc.. It is a great book, I highly recommend it. Page 111:

In 1951 the husband-wife team of Joshua and Esther Lederberg, microbiologists at the University of Wisconsin, demonstrated that their elegantly simple proof that preexisting mutations, not gradual tolerance, accounted for the many instances of new drug resistance… This meant that every new antibiotic became a powerful new force for bacterial evolution, winnowing away every bacterium but the otherwise unremarkable one that could survive its effects. With its competition gone, that lucky mutant could populate, giving rise to a newly resistant colony overnight.

Since bacteria can grow remarkably quickly, eliminating all but a small number just means that the new population boom will come from those few, resistant, ancestors. But that is not the only reason bacteria are so challenging to fight. They have been around billions or years and have survived because they can adapt well. Bacteria, in fact, can get their genes from distantly related bacteria. So if one bacteria gains immunity another bacteria can get that immunity by getting genes from that other bacteria (seems like science fiction but it is actually science fact).

Science Explains: Flame Color

Have you ever wondered why some flames are yellow, while others are blue? Growing up, I was always told that it was a matter of temperature, that hot flames were blue and cooler flames were yellow. While there is a temperature difference, that difference is a “symptom” of what is going on, not the cause of the color difference.
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Does that mean that there is solid stuff inside the candle flame? Let’s find out. Light the candle and be sure it is steady and won’t fall over. Hold the bottom of the plate in the candle flame for a few seconds. When you remove the plate, it has turned black!!! Don’t worry. You have not ruined it. Let it cool for a minute. Remember, it is HOT! Once it has cooled, rub your finger over the black spot. The black rubs off.

Really Old Coral – Over 2,000 Years Old

photo of sea coral (leiopathes_glaberrima)

Worlds oldest animal aged to 4000 years

deep-sea gold corals (Geradia sp.) and black corals (Leiopathes glaberrima, pictured left) indicate these animals live between two and four millennia
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The new findings break all records previously claimed for marine invertebrates like the cold seep tubeworms (estimated 200 years old), quahog clams (estimated 400 years old), as well as the deep-sea wannabees Primnoa spp. and bamboo corals (45 – 300 years old). Given the new results, deep-sea animals can finally measure up to the longevity of the “Methuselah tree”, the Bristlecone Pine, estimated to be near 5000 years old.
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perhaps the most important thing to mention is that gold and black corals are colonial zoantharians. No single polyp is thought to be this old, just the skeletal axis.

How is Coral an animal?

Coral is an animal that belongs to the phylum cnidaria…
During the mating season coral polyp release eggs and sperm into the water (picture below) and when an egg and a sperm meet they form a larva known as a planula…
The baby coral looks like a little tiny jellyfish and it floats around in the water until it finds a hard place to attach to, usually a coral reef. Then it lands and starts to build itself a shell. It builds it by combining carbon dioxide (CO2) and calcium (Ca) in the water to make calcium carbonate (CaCO3) also known as limestone. This shell is shaped like a round vase and the coral polyp lives inside…