Category Archives: Science

Electrical Brain Stimulation Boosts Memory

The technique involves implanting electrodes into the brain: in this case into an area in the limbic system called the hypothalamus, which is thought to control the appetite. When the electrodes were stimulated by electrical impulses the patient began to experience feelings of deja vu.

He then had a sudden perception of being in a park with friends. He felt younger, thought he was around 20-years-old, and his girlfriend of the time was there. He was an observer, and saw the scene in colour. As the intensity of the stimulation increased, details in the scene became more vivid.
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The results suggest it might be possible to use deep brain stimulation directly to boost memory. “We hopefully have found a circuit in the brain which can be modulated by stimulation, and which might provide benefit to patients with memory disorders,” said Professor Lozano. He is now leading a pilot study into whether deep brain stimulation can help people with early Alzheimer’s disease. They are initially testing six patients.

Darwin Day

Find a Darwin Day Celebration near you. Events from hundreds of sites including:

Darwin Day in Italy
University of Oslo, Norway
University of Valencia, Spain
Shrewsbury Darwin Festival, UK (Darwin’s home town)
2008 Darwin Festival, Salem State College, Massachusetts, USA
Darwin Day Lecture, Central Washington University, USA
Darwin Day, Case Western Reserve University, USA

The Mystery of the Voynich Manuscript

image from the Voynich manuscript

A fun read – The Mystery of the Voynich Manuscript:

Voynich asked the leading cryptographers of his day to decode the odd script, which did not match that of any known language. But despite 90 years of effort by some of the world’s best code breakers, no one has been able to decipher Voynichese, as the script has become known. The nature and origin of the manuscript remain a mystery. The failure of the code-breaking attempts has raised the suspicion that there may not be any cipher to crack. Voynichese may contain no message at all, and the manuscript may simply be an elaborate hoax.
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This study yielded valuable insights into the process of reexamining difficult problems to determine whether any possible solutions have been overlooked. A good example of such a problem is the question of what causes Alzheimer’s disease. We plan to examine whether our approach could be used to reevaluate previous research into this brain disorder. Our questions will include: Have the investigators neglected any field of relevant expertise? Have the key assumptions been tested sufficiently?

Dr Gordon Rugg at the Department of Computer Science Keele University – Replicating the Voynich Manuscript

Related: Scientific Method Man – The medieval Voynich Manuscript – in the language of the angels…. or a hoax? – Ancient Greek Technology 1,000 Years Early – Prayer Book Reveals Lost Archimedes Work Studying Ideas at Heart of Calculus – Seeing Patterns Where None Exists

The Science of Kissing

The Differences in Gender — Sealed With a Kiss

In people, kissing to express affection is almost universal. About 90 percent of human cultures do it. One traditional view is that kissing, known scientifically as osculation, evolved from women chewing food for their children and giving it to them mouth-to-mouth, Fisher said.

But, she said, “I’ve never believed that,” adding that similar behavior is found in many species. Birds tap beaks. Elephants shove their trunks in each other’s mouths. Primates called bonobos practice their own version of French kissing. Fisher believes kissing is all about choosing the right mate.

“There’s so much information exchanged when you kiss someone that I just thought it must play a vital role in mate choice, and this paper is elegantly showing that,” Fisher said. A disproportionate amount of the brain, she noted, is geared toward interpreting signals from the mouth.

The research paper – Sex Differences in Romantic Kissing Among College Students: An Evolutionary Perspective

Scientists on Changing Their Minds

When the world’s great scientific thinkers change their minds

The obligation of a scientist to do science by Leon Lederman, Nobel Laureate in Physics (author of The God Particle)

I have always believed that the scientist’s most sacred obligation is to continue to do science. Now I know that I was dead wrong. I am driven to the ultimately wise advice of my Columbia mentor, I.I. Rabi, who, in our many corridor bull sessions, urged his students to run for public office and get elected. He insisted that to be an advisor (he was an advisor to Oppenheimer at Los Alamos, later to Eisenhower and to the AEC) was ultimately an exercise in futility and that the power belonged to those who are elected. Then, we thought the old man was bonkers. But today… A Congress which is overwhelmingly dominated by lawyers and MBAs makes no sense in this 21st century in which almost all issues have a science and technology aspect.

It is important for some scientists to take on other important rolls in society – political leaders, popular authors, business leaders, government officials (regulators etc.), political commentators…

Million-Degree Plasma May Flow throughout the Galaxy

Researcher Manuel GÃ¼del at the Paul Scherrer Institut in Switzerland and colleagues from Switzerland, France and the US have recently observed the plasma flow phenomenon for the first time in the Orion Nebula. Based on images taken with an x-ray satellite called the XMM-Newton, the researchers observed the existence of a million-degree plasma flowing from the nebula into the adjacent interstellar medium, and then into the neighboring superbubble Eridanus.

“Although there has been a theoretical model that predicted hot gas bubbles blown by just one massive star, such has not been detected until we found confirmation in the Orion Nebula,” GÃ¼del told PhysOrg.com. “We didn’t look for it – we actually found this diffuse emission by chance while looking at the many stellar x-ray point sources in the field.
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“Hot gas has been seen in some extremely massive star-formation regions, and some of this gas might have been produced by supernova explosions,” said GÃ¼del. “However, the Orion Nebula is the first region of its (more modest) kind that shows this phenomenon, and there is no supernova that can account for it. Such more modest regions of star formation are naturally more frequent in the galaxy than the more extreme cases. Therefore, we believe that plasma outflows from star-forming regions are widespread.”

Biofuels use Could Worsen Global Warming

Biofuels use could worsen warming (site broke link so link removed)

The biofuels themselves produce less greenhouse gases than fossil fuels, but not nearly enough to offset the carbon dioxide that is released when land is cleared and plowed up to produce crops, the studies said. Carbon dioxide is one of the leading contributors to global warming.

One of the studies released Thursday by the journal Science estimated that ethanol would nearly double the greenhouse emissions over a 30-year period if the impact of land conversion is taken into account.

NSF Awards $50 Million for Collaborative Plant Biology Project

The National Science Foundation (NSF) today announced a $50 million award to a University of Arizona-led team to create the first national cyberinfrastructure center to tackle global “grand challenge” plant biology questions that have great implications on larger questions regarding the environment, agriculture, energy and the very organisms that sustain our existence on earth. The five-year project, dubbed the iPlant Collaborative, potentially is renewable for a second five years for a total of $100 million.

Like no other single research entity, the iPlant Collaborative will provide the capacity to draw upon resources and talent in remote locations and enable plant scientists, computer scientists and information scientists from around the world for the first time ever to collaboratively address questions of global importance and advance all of these fields. It will bring together and leverage the resources and information generated through the National Plant Genome Initiative, enabling more breadth and depth of research in every aspect of plant science.

“We are confident in the positive returns of this substantive investment in basic research,” said NSF Director Arden L. Bement. “The iPlant Collaborative will harness the best and the brightest scholars and research in plant biology in order to tackle some of the profound issues of our day and for our future. Challenges that may need plants for solutions include addressing the impacts of climate change, dwindling oil supply, decreasing agricultural land area, increasing population and environmental degradation.”
Continue reading →

Surprising New Diabetes Data

But these measures are only surrogates for disease. And in many cases, the connection between “better” numbers and better health is tenuous. In the case of cholesterol, many people won’t see a health benefit from lower numbers.

Now comes yet another sobering reminder that lowering a surrogate marker doesn’t necessarily bring better health. On Feb. 6, the National Institutes of Health announced it was halting a key trial for diabetes. Researchers had hoped the trial, dubbed ACCORD (Action to Control Cardiovascular Risk in Diabetes), would show that more aggressive lowering of blood sugar would significantly reduce deaths. Instead, the opposite happened. More people in the intensive treatment group died than in the group getting standard care. “A thorough review of the data shows that the medical treatment strategy of intensively reducing blood sugar below current clinical guidelines causes harm in these…patients,” says Dr. Elizabeth Nabel, director of the National Heart, Lung & Blood Institute.

Scientific study often results in less than clear conclusions, especially in complex systems. There is great difficulty understanding what is actually going on, what interactions are present, what factors are significant, etc.. One of the great problems with the low level of scientific literacy in the USA is so many people think science is about simple absolute truth.

Scientific inquiry, especially related to health care, must attempt to gain insights from confusing signals. To gain scientific literacy one must understand basics concepts, like data is a proxy for what you aim to understand. To understand yourself you need to accept that science is not math. For a long time we are going to have to do our best to build up our understanding of human health (and other complex systems) as best we can. We need to be able to sort out what are solid conclusion, what are guesses, what seem like reasonable explanation and what level of confidence we can have in statements.

It is not enough to learn facts we need to be able to think scientifically and comprehend the subtleties surrounding the advances in scientific understanding. Some criticize newspapers and popular science for providing too simplistic a view of new scientific knowledge. While this can be a problem I really see the problem much more serious if people read obviously overly simplistic articles and don’t understand that it is just scratching the surface. The reader needs to take responsibility too. I enjoy many great articles that gloss over many of the details but provide a quick view of intriguing new breakthroughs.

Cancer Killing Ideas From Honeybees

Honeybee Weapon in War on Cancer

No, researchers haven’t found a beehive-based cure (though major royal jelly, the wondrous protein concoction that turns lowly workers into queens, may have anti-cancer properties.) But bee colonies experience their own type of cancer, and maybe human researchers can learn from their victories.
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Like Amdam said, it’s not clear how the honeybees won. Perhaps the successful colonies produced bees adapted to noticing the intruder; perhaps it produced individual bees whose interactions caused some sort of superorganism-wide shift. And maybe when we figure that out, we’ll have some fresh ideas for fighting cancer — maybe not for tweaking our own cells, but for customized nanomolecule cancer hunters.