Category Archives: Science

New and Old Ways to Make Flu Vaccines

New and Old Ways to Make Flu Vaccines by Nell Greenfieldboyce, NPR:

Standard Practice
Pros: Millions of Americans receive this [standard] vaccine every year. It’s safe and well tolerated. Its production begins in hens’ eggs — a tried and true technology for 50 years.
Cons: Eggs must be ordered many months in advance, and millions of doses require millions of eggs.

Live-Attenuated Vaccine
Pros: This newer method of production results in a vaccine that has a flu virus that is crippled, so it can’t cause disease. But the virus is not killed, as is the case in the standard vaccine. The vaccine also can be given as a nasal spray.
Cons: More expensive than standard vaccine, and also produced in eggs. Not approved for young children or older people.

Cell-Based Vaccine
Pros: This vaccine can be produced in giant vats of living cells. Such a production method means it can be scaled up much faster than egg-based vaccines, making it more useful in a pandemic. Several versions have been tested successfully in people.
Cons: Won’t be widely available for a few years. Clinical trials are under way, but no flu vaccine made this way is currently approved by the Food and Drug Administration.

Related: MRSA Vaccine Shows PromiseAntibiotics Too Often Prescribed for Sinus Woes

Vast Garbage Float in the Pacific Ocean

Feds want to survey, possibly clean up vast garbage pit in Pacific:

Charles Moore, the marine researcher at the Algalita Marina Research Foundation in Long Beach who has been studying and publicizing the patch for the past 10 years, said the debris – which he estimates weighs 3 million tons and covers an area twice the size of Texas – is made up mostly of fine plastic chips and is impossible to skim out of the ocean. “Any attempt to remove that much plastic from the oceans – it boggles the mind,” Moore said from Hawaii, where his crew is docked. “There’s just too much, and the ocean is just too big.”

The trash collects in one area, known as the North Pacific Gyre, due to a clockwise trade wind that circulates along the Pacific Rim. It accumulates the same way bubbles gather at the center of hot tub, Moore said. A two-liter plastic bottle that begins its voyage from a storm drain in San Francisco will get pulled into the gyre and take weeks to reach its place among the other debris in the Garbage Patch. While the bottle floats along, instead of biodegrading, it will “photodegrade,” Moore said – the sun’s UV rays will turn the bottle brittle, much like they would crack the vinyl on a car roof. They will break down the bottle into small pieces and, in some cases, into particles as fine as dust.

Related: The Sea CrisisFishy Future?South Pacific to Stop Bottom-trawling

Open Access Legislation May Be Included in HHS Budget Bill

Open Access to Research Funded by U.S. Is at Issue by Rick Weiss:

The idea is that consumers should not have to buy expensive scientific journal subscriptions — or be subject to pricey per-page charges for nonsubscribers — to see the results of research they have already paid for with their taxes. Until now, repeated efforts to legislate such a mandate have failed under pressure from the well-heeled journal publishing industry and some nonprofit scientific societies whose educational activities are supported by the profits from journals that they publish.

But proponents — including patient advocates, who want easy access to the latest biomedical findings, and cash-strapped libraries looking for ways to temper escalating subscription costs — have parlayed their consumer-friendly “public access” message into legislative language that has made it into the Senate and House versions of the new HHS bill.

The opponents of open science are lobbying to keep scientific research funded by taxpayers unavailable to the public. As I have said before it is time to stop supporting those who attempt to stop scientific progress. The out of date thinking behind closed access journals should be discouraged and those journals fighting progress should not be supported. This legislation would bring openness to federal research in a similar manner to the steps taken by Howard Hughes Medical Institute announced for research they fund.

Related: Publishers Continue to Fight Open Access to ScienceScience Journal Publishers Stay StupidI Support the Public Library of ScienceOpen Access Legislation supported by 25 leading university provosts (2006)

The Study of Bee Colony Collapses Continues

The attempts to discover the causes of the die off of bees in the USA continues. This effort provides a good example of the difficulty of learning what really happens around us. Often, once things are worked out, and explained they seem simple and even obvious. But while trying to figure events taking place (like the bee colony collapses), scientists have significant challenges. The hard work and the application of scientific concepts by scientists allow us to learn and adapt. I think the difficulty can paint a valuable picture of what science is about. That search for understanding is wonderful to see and something fundamental to the human experience. Disappearing Bee Mystery Deepens

One year ago, beekeepers across the country began to report that worker bees were inexplicably abandoning their hives and leaving the brood to die. Although firm statistics are hard to come by, so-called colony collapse disorder may have afflicted as many as 25% of U.S. beekeepers and perhaps others around the world. Possible culprits included pesticides, parasites, and chronic stress from poor nutrition and the long-distance truck rides that many commercial hives undergo.

For that matter, no one has yet shown that IAPV can cause colonies to collapse. “Until you have introduced the virus and caused disease, you’re just postulating,” cautions Bruce Webb, an entomologist at the University of Kentucky in Lexington. “The conclusive data are not in.”

Related: Bye Bye BeesVirus Found to be One Likely Factor in Bee Colony Collapse Disorder

Presidential Early Career Awards for Scientists and Engineers

The Presidential Early Career Awards for Scientists and Engineers, established in 1996, honors the most promising researchers in the Nation within their fields. Nine federal departments and agencies annually nominate scientists and engineers who are at the start of their independent careers and whose work shows exceptional promise for leadership at the frontiers of scientific knowledge. Participating agencies award these talented scientists and engineers with up to five years of funding to further their research in support of critical government missions.

Awards were announced today – links to some of the awardees:

  • Jelena Vuckovic, Assistant Professor of Electrical Engineering, Stanford University
  • Matthew Rodell, Physical Scientist, NASA
  • Katerina Akassoglou, Assistant Professor of Pharmacology, University of California, San Diego
  • Carlos Rinaldi, Associate Professor of Chemical Engineering University of Puerto Rico at Mayagüez
  • Ahna Skop, Assistant Professor of Genetics, University of Wisconsin-Madison
  • Krystyn J. Van Vliet, Assistant Professor of Materials Science and Engineering, MIT
  • Odest Chadwicke Jenkins, Assistant Professor, Department of Computer Science, Brown University

Related: 2006 MacArthur FellowsYoung Innovators Under 35Presidential Early Career Award for Scientists and Engineers (2006)NSF Release on 2007 awardees that are also NSF CAREER awardees

The Importance of Science Education

The Science Education Myth by Vivek Wadhwa:

The authors of the report, the Urban Institute’s Hal Salzman and Georgetown University professor Lindsay Lowell, show that math, science, and reading test scores at the primary and secondary level have increased over the past two decades, and U.S. students are now close to the top of international rankings. Perhaps just as surprising, the report finds that our education system actually produces more science and engineering graduates than the market demands.

The study certainly sounds interesting. I can’t find it (update Vivek Wadhwa provided the link – which will work Monday, also see his comment below), but found an article (which wasn’t easy) by the authors of the report: The Real Technology Challenge. The main point of the article, The Real Technology Challenge, seems to be that the USA should focus on globalization (and focus on educating scientists and engineers to work in a global world).

As I have said before I disagree with those that believe the USA is producing more science and engineering graduates than the market demands. Smart leaders know the huge positive impacts of a large, well educated science and engineering workforce.

Countries that succeed in producing more quality graduates while creating the best economic environment to take advantage of technology innovation (follow this link – it is one of the most important posts about what makes silicon valley so powerful a force at doing just that) are going to benefit greatly. My guess is the USA will be one of those countries; not by reducing the focus on science and engineering education but by increasing it. If not, other countries will, and the USA will suffer economically. The USA also needs to continue to push the economic and entrepreneurship advantages – doing that well is very difficult to achieve and the USA maintains a stronger advantage in that realm – but I will be very surprised if other countries don’t continue to make gains in this area. Even so doing so is much more challenging than just improving education (which is difficult itself just not nearly as difficult) and the USA can continue to benefit from this combination with the right policies.

Related: Economic Strength Through Technology LeadershipHouse Testimony on Engineering EducationFilling the Engineering GapBest Research University Rankings (2007)Most IT Jobs Ever in USA TodayUSA Under-counting Engineering GraduatesScience, Engineering and the Future of the American EconomyS&P 500 CEOs – Again Engineering Graduates LeadHighest Paid Graduates: Engineers

Primary Science Education in California

Lawrence Hall of Science at the University of California, Berkeley Science Survey:

California, including the San Francisco Bay Area, is home to much US innovation in science and technology. Recent national reports have illuminated the importance of science education in the elementary grades and described concerns for US leadership in science,1 the importance of fostering interest in science early in life,2 and issues with promoting high quality science instruction in the elementary grades,3 nationally,4 and in California.5

At the same time, this region produces inadequate achievement results among its students. Results of the 2005 National Assessment of Education Progress 4th grade science test indicate that California ranked 2nd lowest of all states on eighth grade science achievement, only above Mississippi. During spring 2007, results on the 5th grade California Standards Test (CST) in Science indicate that only 37% of California students and approximately 46% of Bay Area students scored proficient or above6. This means that even in the Bay Area, over half the 5th graders are failing to reach proficiency in science.

Eighty percent (80%) of K–5th grade multiple-subject teachers who are responsible for teaching science in their classrooms reported spending 60 minutes or less per week on science, with 16% of teachers spending no time at all on science.

Related: The Future is EngineeringImproving Elementary Science EducationPurdue Graduate Fellows Teach Middle School Sciencek-12 Science Education Podcast

Scientists Denounce Global Warming Report ‘Edits’

Scientists Denounce Global Warming Report ‘Edits’:

The original, unedited testimony presented to Congress by Dr. Julie Gerberding, director of the Centers for Disease Control and Prevention (CDC) and obtained by ABC News was 14 pages long, but the White House Office of Management and Budget edited the final version down to a mere six pages.

Scientists and public health organizations called the move “frustrating,” “terrible” and “appalling.” The edits essentially deleted all sections that referred to climate change as a public health concern — including the risks of increased food-borne and waterborne diseases, worsening extreme weather events, worsening air pollution and the effect of heat stress on humans.

“Dr. Gerberding is the lead of the premiere public health agency in the U.S.,” said Kim Knowlton, a science fellow on global warming and health at the National Resources Defense Council in New York. “It’s shocking that she was not allowed to say in a public discussion some of these vital details.

Political reasons for modifying testimony are not amazing. But when political edits to science testimony are too large you can really open up some questions about what is driving testimony. And those questions should be asked. Lets not allow science to be hidden and not allow the public to hear what the scientists working for us have to say – let the debate be open and public.

Related: The A to Z Guide to Political Interference in ScienceDiplomacy and Science Research

Innovation Academy for High School Students

Innovation Academy students get their feet wet

“They teach us about ocean life and animals — I like that kind of stuff,” she said. “It’s something different.”

Moody High School Innovation Academy students will make three more trips to the field station this semester and another five in the spring. Then they’ll gather up statistics and try to determine environmental trends for the station.

The trips are possible through an agreement made late this summer between the 2-year-old institute and Corpus Christi Independent School District. The Innovation Academy — one of seven academies at Moody — is in its first year and enrolls 75 Moody ninth-grade students and 105 Cunningham Middle School sixth-graders.

“Our kids are becoming very involved in the makeup of Laguna Madre plants and animals, as well as how to document their existence,” said Tina Dellinger, Texas Science Technology Engineering and Math district coordinator. The Innovation Academy is in its second year of a two-year, $750,000 Texas Science Technology Engineering and Math Initiative grant that last year funded academy planning and training and this year is funding its first activities.

Related: Engineers of the FutureBuilding minds by building robotsLego LearningFun k-12 Science and Engineering Learning

China Reaches for the Moon

China’s Long March to the Moon

The missions by China and Japan are part of a broader resurgence of interest in the moon by space agencies around the world. The U.S. and India also are planning unmanned lunar-exploration missions next year. It is the biggest burst of such work since the 1970s. The last humans to stand on the moon were American astronauts from the Apollo 17 mission in 1972.

For China, the aim is explicitly political, as well as scientific. “Lunar exploration reflects a country’s comprehensive national power,” said Ouyang Ziyuan, the chief scientist for China’s moon program, in an interview with the official Communist Party newspaper, People’s Daily. It will “raise our international prestige and strengthen the cohesion of our people.”

China aims to have a unmanned mission to the moon in 2012 and a manned mission to the moon by 2020.

Related: China Prepares for Return of Shenzhou Helium-3 Fusion ReactorChina’s Science and Technology PlanAsia: Rising Stars of Science and EngineeringBest Research University Rankings (2007)