How Does the Immune System Remember

Scientists find key to immune system’s ability to remember

The protein, which scientists call Lck, is essential for immune system T cells – white blood cells that attack virus-infected cells, foreign cells and cancer cells… Lck is important in helping “naive” T cells – those cells that have never been exposed to a particular pathogen – capture the receptor template of the invading agent and store it for future reference… Following infection or vaccination, Lck initiates a biochemical chain of events that vastly increases the number of T cells that march off to combat the invader.

After the infection subsides, the number of T cells marshaled to fight that agent decreases dramatically. But a smaller subset, known as “memory” cells, retains the imprint of its previous encounter should the pathogen make a return appearance. According to the study, while Lck primes naive cells to fight a pathogen, it is not required by memory cells, which initiate the fast and furious response when that same pathogen comes calling again years later. Unlike naive T cells, which are confined to the lymphatic system, memory T cells are found everywhere in the body, enabling them to sense and react more quickly when an infectious agent is reencountered.

Fun Fungi

Impudence, Thy Name is Mushroom

Fungi, on the other hand, are fundamentally alien.
…
Some lurk in the Earth, spreading out over hundreds of acres. Others live inside insects, forcing them to climb to the tip of a blade of grass, so that they can shower their spores down on new victims. Instead of ingesting their food, fungi dump their digestive enzymes into their surroundings and suck up the ensuing goo. Their reproductive cycles are like labyrinths. And of the estimated 1.5 million species of fungi on Earth, scientists have identified only five percent.

Flushed Drugs Pollute Water

Flushed drugs pollute water by Ron Seely (site broke the link so I removed it):

An extensive nationwide study by the U.S. Geologic Survey has found evidence of pharmaceuticals including antibiotics and hormonal drugs, such as birth control pills, in surface waters throughout the nation.
…
Whether the presence of drugs in water translates into human health impacts is still being studied. But research has shown that drugs containing hormones such as estrogen are causing changes and deformities in fish and other aquatic creatures.

The World Health Organization indicates that human risk assessments have shown low concentrations of pharmaceuticals in drinking water have a negligible health risk. But WHO points out that long-term exposures have not been evaluated, especially in populations with other illnesses or with compromised immune systems. Also, according to the WHO, antibiotics in water supplies are a potential concern because the most frequently used antibiotics are becoming less effective as the infections they are designed to combat become resistant.

Ocean Warming’s Effect on Phytoplankton

Ocean warming’s effect on phytoplankton:

When the climate warms, there is a drop in the abundance of the ocean’s phytoplankton, the tiny plants that feed krill, fish and whales, according to scientists who say new research offers the first clues to the future of marine life under global warming.

Ocean temperatures have generally risen over the last 50 years as the atmosphere warms. And now nine years of NASA satellite data published today in the journal Nature show that the growth rate and abundance of phytoplankton around the world decreases in warm ocean years and increases in cooler ocean years.

Arctic Sharks

Arctic Shark photo

Arctic sharks found in QuÃ©bec by Brian Lin:

The Greenland shark typically inhabits the deep, dark waters between Greenland and the polar ice cap. At over six metres long and weighing up to 2,000 kilograms, it is the largest shark in the North Atlantic and the only shark in the world that lives under Arctic ice. Once heavily harvested for its vitamin A-rich oil — as many as 50,000 were caught annually according to a 1948 estimate — little is known about the animal.

Physicists Find Long Sought Particle

Long the fixation of physicists worldwide, a tiny particle is found:

After decades of intensive effort by both experimental and theoretical physicists worldwide, a tiny particle with no charge, a very low mass and a lifetime much shorter than a nanosecond, dubbed the “axion,” has now been detected by the University at Buffalo physicist who first suggested its existence in a little-read paper as early as 1974.
…
“We identified each vertex for each electron pair and we would not accept any electron pair unless we knew its vertex,” he said. “There was a congestion of all kinds of low mass particles, including axions, near the detector. The background has to be filtered out from this congestion in order to obtain the signal of the axion.”

Water flowed ‘recently’ on Mars

Two gullies that were originally photographed in 1999 and 2001, and imaged again in 2004 and 2005, showed changes consistent with water flowing down the crater walls, according to the study.

In both cases, scientists found bright, light-coloured deposits in the gullies that were not present in the original photos. They concluded that the deposits – possibly mud, salt or frost – were left there when water recently cascaded through the channels.

Other scientists think it possible that gullies like this were caused not by water but by liquid carbon dioxide.

Why Insects Can’t Fly Straight at Night

Why Insects Can’t Fly Straight at Night by Nicolas van der Leek:

Well, it’s simple really. The structure of their eyes (moths, mantises and plenty of other bugs) is distinctive. Under the microscope their eyes resemble a bunch of long tubes. So when the moth or mantis encounters an artificial light, suddenly when it swoops by the light slips out of its field of vision, and it swings round to get it to shine back into the tubes, and at a constant angle. Hence the chaotic, circular flying. They’re attempting to keep the light coming in at the same angle into the tube structure of their eyes.

Increasing American Fellowship Support for Scientists and Engineers

A great research paper is available today from the Brookings Institution: Investing in the Best and Brightest: Increased Fellowship Support for American Scientists and Engineers by Richard B. Freeman. For those interesting in science and engineering education and/or economic policy I recommend it.

In 2005, the United States employed about 31 percent of the world’s scientist and engineer researchers and financed 35 percent of R&D while accounting for 5 percent of the world’s population and 21 percent of the world’s GDP…
The U.S. share of global science and engineering activity is declining, however, and will continue to decline

I agree the declining trend is likely to continue, mainly due to the improvement of science and engineering efforts worldwide, see, for example: Diplomacy and Science Research and – U.S. Slipping on Science – Phony Science Gap?.

The growth of high-tech employment in Silicon Valley and in university-based locations of scientific excellence suggests that innovation, production, and employment in high-tech fields occur largely in areas strong in basic science.10 The supply of scientists and engineers is a major factor in the location of these centers of excellence.

Again I agree. I am in danger of confirmation bias since this report basically reinforces what I believe – so of course I find it worthwhile.

While no one can be sure of the particular areas where an increased number of scientists and engineers might make their greatest contribution, our recent history is filled with examples where young innovative researchers have made major contributions to economic progress: The Internet. The biotech industry. The PC. The mathematics of cryptography that underpins Internet commerce.

Again I agree. This is why so many countries have been devoting significant resources to improving their science and technology infrastructure – the economic benefits of doing so.
Continue reading →

What Graduates Should Know About an IT Career

Here is some decent and simple advice. It is obviously not comprehensive or completely accurate but a is a very quick addition to other thoughts on the topic: What every graduate should know before entering the IT industry:

Your whole career in IT will be spent updating your skills
This follows on from the last point. If your skills become out of date, you will become vulnerable to losing your career. Because of this, IT is a career where it is difficult to thrive without having a real passion for it. Your employer may send you on expensive training courses, but unless you read up and experiment in your own time, you’re going to fall behind.

See more science, engineering and technology career tagged posts.