‘Virtually untreatable’ TB found

‘Virtually untreatable’ TB found:

TB presently causes about 1.7 million deaths a year worldwide, but researchers are worried about the emergence of strains that are resistant to drugs.

Drug resistance is caused by poor TB control, through taking the wrong types of drugs for the incorrect duration.

Multi-drug resistant TB (MDR TB), which describes strains of TB that are resistant to at least two of the main first-line TB drugs, is already a growing concern.

Globally, the WHO estimates there are about 425,000 cases of MDR TB a year, mostly occurring in the former Soviet Union, China and India.

TB Related posts: Extensively Drug-resistant Tuberculosis (XDR TB), May 2007Deadly TB Strain is Spreading, WHO Warns, Mar 2007Tuberculosis Pandemic Threat, Jan 2007

Related: Evolution of Antibiotic ResistanceOveruse of Antibiotics

Most Dinosaurs Remain Undiscovered

Dinosaurs remain to be discovered (bozos broke link so I deleted it – poor usability)

Peter Dodson of the University of Pennsylvania and Steve Wang of Swarthmore College estimate that 71 percent of all dinosaur genera — groups of dinosaur species — have yet to be discovered.

“It’s a safe bet that a child born today could expect a very fruitful career in dinosaur paleontology,” Dodson said in a statement.

The estimates are based on the rates of discovery — about 10 to 20 annually — and the recent increase in finds of fossils in China, Mongolia and South America.

Vast Majority of Dinosaurs Still to Be Found, Scientists Say, National Geographic:

The pair predicts that scientists will eventually discover 1,844 dinosaur genera in total—at least 1,300 more than the 527 recognized today from remains other than isolated teeth.

What’s more, the duo believes that 75 percent of these dinos will be discovered within the next 60 to 100 years and 90 percent within 100 to 140 years, based on an analysis of historical discovery patterns.

Higher Education Worldwide

The U.S. Edge In Education by Richard H. Brodhead, president of Duke University:

This will inevitably mean improving in areas where Asia is strong: building stronger foundational skills in early grades, making sure more students persist in so-called STEM subjects (science, technology, engineering and math), supplying more good math and science teachers, and other steps.

In particular, we need to promote everything in our system that breeds initiative, independence, resourcefulness and collaboration. One of these is the liberal arts model of education. The schooling that trains students in many different disciplines makes them more flexible at shifting among a range of challenges and approaches. It also equips them to bring different sets of tools to bear on complex problems, allowing them to improvise new solutions by making new connections.

Related: USA Under-counting Engineering GraduatesScientific Innovation and Economic GrowthThe World’s Best Research UniversitiesScience and Engineering Doctoral Degrees WorldwideQuality vs. Quantity in EngineeringFilling the Engineering Gap

Open Course Ware from Japan

Soccer Robots from Osaka University

A number of Japanese Universities are creating open courseware, in cooperation with MIT’s OpenCourseWare initiative (which has spawned the OCW Consortium).

Osaka University OpenCourseWare offers courses in English including: Theory in Materials Science | Fluid-Solid Multiphase Flow

Kyoto University OpenCourseWare aims to:

share information in consideration of the fact that sixty percent of visitors to MIT’s OCW project come from Asia. We will make active use of Japanese in building OpenCourseWare, to recruit talented students from all over Asia as well as to promote the Kyoto University education, with Kyoto’s culture and traditions, to the world at large.

Many of the courses are available in Japanese, some are available in English, including: Applied Pharmacology

Tokyo Tech OpenCourseWare courses include: Advanced Signal ProcessingGuided Wave Circuit Theory and Mixed Signal systems and Integrated Circuits.

The Nagoya University OpenCourseWare brings free courseware to the Internet. Currently several courses are available in English including, Basics of Bioagricultural Sciences. They aim to post 25 courses initially.
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Great Nanotechnology Overview

Reporting Risk Assessment of Nanotechnology: A reporter’s guide to sources and research issues (pdf) by Trudy E. Bell:

The article discusses how reporters should investigate the risks with nanotechnology, and in doing so provides a good introduction to concepts in nanotechnology:

If engineered nanomaterials have physical properties different from their bulk counterparts, might they also pose new risks to human health in their manufacture, use, and disposal?

As yet, no one knows. Current data basically suggest “it depends.” But researchers both in government and private
industry are keen to find out.

The potential for nanotechnology is amazing but as we have said before the risks presented by nanotechnology also need careful study.

At the nanoscale, fundamental mechanical, electronic, optical, chemical, biological, and other properties may differ significantly from properties of micrometer-sized particles or bulk materials.

One reason is surface area. Surface area counts because most chemical reactions involving solids happen at the surfaces, where chemical bonds are incomplete. The surface area of a cubic centimeter of a solid material is 6 square centimeters—about the same as one side of half a stick of gum. But the surface area of a cubic centimeter of 1-nm particles in an ultrafine powder is 6,000 square meters—literally a third larger than a football field.

Engineering Student Contest Winners Design Artificial Limb

St. Joseph's College of Engineering students

St. Joseph’s engineering college students win design contest, India:

Three students of St. Joseph’s College of Engineering received a cash award of Rs.50,000 for their prototype of an artificial limb, presented in the `National Level Engineering Students Design Contest’.

The contest, organised by the Product Development and Management Association (PDMA), was aimed at encouraging engineering students to design innovative products.

Organising secretary K. Chandrasekaran said the event was held to address the gap between education and industry, promoting design education and take students to the logical end of working prototypes.

Related: Concentrating Solar Collector wins UW-Madison Engineering Innovation AwardStanford Students Win $10,000 for Aneurysm TreatmentHopeful About India’s Manufacturing SectorIndia Manufacturing Data – compared to other countriesIndian National Level Engineering Students Design Contest web site

Nobel Laureates Speaking to High School in Japan

Nobel laureates aiming to spur creativity / Shirakawa, Tanaka to give students lecture

Shirakawa became interested in science journalism, and even sat in during lectures offered by the Japan Association of Science and Technology Journalists. He is now enthusiastic about giving lectures to, and teaching, young scientists.

Research is important for scientists, but it is also important that they share their knowledge with the public, and people to better understand the subject, he said.

Shirakawa graduated from the Science and Engineering Department of Tokyo Institute of Technology, where he obtained a doctorate in engineering in 1966.

In 2000, he won the Nobel Prize in Chemistry for the discovery of conductive polymers.

Our previous post, Scientists and Students, discussed having practicing scientists address students. Scientist say they are too busy and do not get credit for such efforts – hopefully these Nobel prize winners can help show how important such direct contact can be.

Related: Science Education in the 21st Centuryblog posts about k-12 science and engineering educationChildrens View of Scientists in the United Kingdom20 Scientists Who Have Helped Shape Our WorldNobel Laureate Discusses Protein Power

Oliver Sacks podcast

Oliver Sacks is a neurologist and author of interesting and entertaining books including: The Man Who Mistook His Wife For A Hat: And Other Clinical Tales. He is most known for explaining the remarkable case histories of extreme brain trauma, and how those instances allow us to learn about the brain.

Listen to webcast of his interview on NPR’s Science Friday. More blog posts on science and engineering podcasts

The Fully Immersive Mind of Oliver Sacks, Wired
Another Science Friday interview with Oliver Sacks from 1997.

Related: blog posts relating to health and biologyWeekly Science PodcastsGoogle Tech Webcastsk-12 Science Education Podcast

Electrical Engineering Future

The future of electrical engineering

The article discusses many of the explanations for the lack of growth in engineering graduates in the USA and reasons for studying engineering. Some related posts from our blog: Top degree for S&P 500 CEOs? EngineeringLucrative college degreesUSA Engineering JobsGlobal Share of Engineering WorkEngineers in the Workplace

Indeed, a degree in electrical engineering can open many doors, in part because electrical engineering is so broad. Electrical engineers have taken on many tasks that you might expect people with other technical degrees to do. Semiconductor processing, for example, is highly populated by electrical engineers, but its basis is in physics and chemistry. Other areas include optics (as applied to communications), aerospace engineering, and even life sciences. “A lot of people don’t realize that a lot of biomedical devices are actually electrical devices,” noted Georgia Tech’s May.

More related posts: Electrical Engineering StudentSurvey of Working EngineersUSA Under-counting Engineering Graduates

Engineered Immune Cells Shrink Tumors

Tumors Shrunk by Engineered Immune Cells, Scientists Say by Stefan Lovgren, on an extermintal treatment with 17 patients so far:

“This is the first example of an effective gene therapy that works in cancer patients,” said Steven Rosenberg, chief of surgery at the National Cancer Institute in Bethesda, Maryland, and leader of the research team.

The therapy has so far been applied only to melanoma patients. But the researchers are optimistic that their treatment can be used for many other types of cancer.

The team has already engineered similar immune cells for more common tumors, such as breast, lung, and liver cancers.

His team focused on T (thymus) cells, a type of specialized immune cell that can learn to recognize and attack specific “foreign” objects, such as the cancer cells that make up tumors.

In the new study, researchers created tumor-fighting cells by harvesting normal T cells from melanoma patients and genetically engineering these cells to carry receptor proteins on their surfaces that recognize cancer markers.