2005 intercollegiate Genetically Engineered Machine competition

Davidson College: Kristen DeCelle 2006 and Andrew Drysdale 2007

2005 Intercollegiate Genetically Engineered Machine Competition. Thirteen schools participated in the 2005 Intercollegiate Genetically Engineered Machine competition (iGEM 2005): Berkeley, Caltech, Cambridge, Davidson, ETH Zurich, Harvard, MIT, Oklahoma, Penn State, Princeton, Toronto, UCSF, and UT Austin. Learn about and sign up for the 2006 competition.

Photo of Davidson College students: Kristen DeCelle ’06 and Andrew Drysdale ’07. Davidson Students “Ace” Presentation at MIT Synthetic Biology Competition.

The Davidson team-“The Synth-Aces,” a word play on enzymes called synthases-presented their design of a genetically-engineered, E. coli-based “digital decoder.” The device detects which combination of three common chemicals (with eight combinations possible) is present, and then displays a human-readable number that glows in the dark. The number is produced by genetically customized bacteria that grow in a familiar pattern of a digital numeric display. The resulting readouts of “0” through “7” correspond to the specific chemical combination detected in solution. One real world application of a decoder device might be to monitor water for contaminants or toxins.

The Innovation Agenda

Democrat’s are proposing an Innovation Agenda, including:

Educate 100,000 new scientists, engineers, and mathematicians in the next four years by proposing a new initiative, working with states, businesses, and universities, to provide scholarships to qualified students who commit to working in the fields of innovation.

Place a highly qualified teacher in every math and science K-12 classroom by offering upfront tuition assistance to talented undergraduates and by paying competitive salaries to established teachers working in the fields of math and science; institute a “call to action” to professional engineers and scientists, including those who have retired, to join the ranks of our nation’s teachers.

Create a special visa for the best and brightest international doctoral and postdoctoral scholars in science, technology, engineering and mathematics.

Make college tuition tax-deductible for students studying math, science, technology, and engineering.

They also propose doubling the funding for the National Science Foundation. Making promises about what you will do is much different than actually doing something: lets see what actually happens.

Currently the United States has over $8,000,000,000,000 (that is over $8 trillion – see current count) in debt (increasing by over $400 Billion a year). That brings every person’s share to over $27,000. Given that, it seems reckless to just add spending without either cutting something else or increasing taxes and I don’t see those details in the innovation agenda. Of course, my opinion on that being reckless may not be shared by a majority choosing to spend more money – after all they have been adding to that debt at a record pace the last few years.

To me, the most realistic federal action, given the role of the federal government (k-12 education is primarily a state and local responsibility) is the scholarship proposal but lets see what actually happens. In July we posted about proposed Science and Engineering Fellowships Legislation (which also seems like a good idea). We have not been able to find out about any progress on that legislation. From the November AAAS S&T newsletter:

Meanwhile, across the Capitol, Senators Joe Lieberman (D-CT) and John Ensign (R-NV) are currently drafting bipartisan legislation to implement a series of policies based on the “National Innovation Initiative” report from the Council on Competitiveness. The legislation, which the senators originally planned to introduce in September, has reportedly been delayed by lack of agreement on its immigration provisions.

I am not certain whether the legislation being worked on includes the fellowships or not (though I would guess that it does).

A Decade of Progress for Women in Science …

A Decade of Progress for Women in Science … by Nancy Hopkins

In 1995 it was unimaginable that within 10 years the presidents of Princeton University, Massachusetts Institute of Technology, University of Michigan, and University of California at San Diego would all be women, and remarkably, women scientists.
…
The percentage of women faculty at MIT is climbing, slowly. In 2004, 13% of faculty in the School of Science and 14% of the School of Engineering were female, up from 8% and 6%, respectively, in 1993. Women who make it to the top in science have long known what holds many women in science back: family demands and bias. But until recently both topics were taboo. A critical step to making progress for women in science has been to put these problems on the agenda.

Progress is being made and continued progress is needed. The percentage of women studying engineering is still very low. And the recent talk in the blogosphere about how many potential engineers are turned away shows that not just women choose to turn away.

We should work to make the option of pursuing a science and engineering path more desirable for those who are interested. Still, it seems progress is being made in including more women on the path to careers in science and though engineering is lagging, progress is being made there also.
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Science Toys You Can Make With Your Kids

Science Toys You Can Make With Your Kids

Photo: the simplest steam engine you will ever see. It has no valves, no moving parts (in the traditional sense of the phrase), and yet it can propel it’s little boat easily across the largest swimming pool or quiet duck pond.

The site includes many simple projects to create toys and teach scientific principles in a fun way with simple materials. Gonzo Gizmos, is the book the site is based on.

Projects include: the impossible kaleidoscope, a simple rocket engine, building a radio in 10 minutes and building your own solar battery.

This cool site is definitely worth a visit.

What Ails India’s Software Engineers?

India does not produce enough good computer engineers and those it does are good at theory but not very well equipped to handle the practical aspects.’
— Microsoft Chief Technical Officer Craig Mundie

What Ails India’s Software Engineers? is an interesting series of 3 articles by Rediff exploring the state of India’s software engineering industry.

From its 113 universities and 2,088 colleges — many of which teach various engineering disciplines — India produces nearly 350,000 engineering graduates every year. All of Europe produces 100,000 engineering graduates a year, and America produces only 70,000.

But, the quality of Indian engineers is questionable, says Madhavan, who has had a career spanning four decades and is now advisor to several engineering colleges in Karnataka and Kerala.
“That is because of the lack of trained faculty and the dismal State spending on research and development in higher education in the country,” he says.

Part of what makes this article interesting is it challenges the accepted wisdom. The article offers an interesting perspective and some details that are not well understood.

In the 1980s, India had just 158 engineering colleges. That number has jumped to 1,208 in the last two decades, mainly because of the information technology boom and the ever-burgeoning capitation fee that self-financing colleges charge.

Every year, these engineering colleges admit about 350,000 students. Apart from this, nearly 3,500 students are absorbed into the seven premier Indian Institutes of Technology.

GAO Report: Federal Science, Technology and Engineering Trends

GAO Report: Federal Science, Technology, Engineering, and Mathematics Programs and Related Trends

13 federal civilian agencies reported spending about $2.8 billion in fiscal year 2004 for 207 education programs designed to increase the numbers of students and graduates or improve educational programs in
STEM (Science, Technology, Engineering and Math) fields. NSF and NIH each account for a bit over 1/3 of the spending.

University officials frequently cited teacher quality as a key factor that affected domestic students’ interest in and decisions about pursuing STEM degrees and occupations. Officials at all eight universities we visited expressed the view that a student’s experience from kindergarten through the 12th grades played a large role in influencing whether the student pursued a STEM degree.
…
officials at many of the universities we visited told us that some teachers were unqualified and unable to impart the subject matter, causing students to lose interest in mathematics and science.

Estimated Changes in Numbers of International Students in STEM fields by Education Levels from the 1995-1996 Academic Year to the 2003-2004 Academic Year

Education level	Number of international students, 1995-1996	Number of international students, 2003-2004	Percentage change
Bachelor’s	31,858	139,875	+339
Master’s	40,025	22,384	-44
Doctoral	36,461	7,582	-79
Total	108,344	169,841	+57

Bannanas Going Going Gone

Can This Fruit Be Saved? by Dan Koeppel, Popular Science:

The banana as we know it is on a crash course toward extinction. For scientists, the battle to resuscitate the world’s favorite fruit has begun…

. It also turns out that the 100 billion Cavendish bananas consumed annually worldwide are perfect from a genetic standpoint, every single one a duplicate of every other. It doesn’t matter if it comes from Honduras or Thailand, Jamaica or the Canary Islands—each Cavendish is an identical twin to one first found in Southeast Asia, brought to a Caribbean botanic garden in the early part of the 20th century, and put into commercial production about 50 years ago.

That sameness is the banana’s paradox. After 15,000 years of human cultivation, the banana is too perfect, lacking the genetic diversity that is key to species health. What can ail one banana can ail all. A fungus or bacterial disease that infects one plantation could march around the globe and destroy millions of bunches, leaving supermarket shelves empty.
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What can ail one banana can ail all. A fungus or bacterial disease that infects one plantation could march around the globe and destroy millions of bunches, leaving supermarket shelves empty.

A wild scenario? Not when you consider that there’s already been one banana apocalypse. Until the early 1960s, American cereal bowls and ice cream dishes were filled with the Gros Michel, a banana that was larger and, by all accounts, tastier than the fruit we now eat.

Gates Millennium Scholars

Gates Millennium Scholars, funded by a grant from the Bill & Melinda Gates Foundation, was established in 1999 to provide outstanding low income African American, American Indian/Alaska Natives, Asian Pacific Islander American, and Hispanic American students with an opportunity to complete an undergraduate college education in any discipline area of interest.

Continuing GMS Scholars may request funding for a graduate degree program in one of the following discipline areas: education, engineering, library science, mathematics, public health or science.

Scientists crack 40-year-old DNA puzzle

Scientist at University of Bath: Stefan Bagby, Jean van den Elsen and Huan-Lin Wu

Scientists crack 40-year-old DNA puzzle and point to ‘hot soup’ at the origin of life:

A new theory that explains why the language of our genes is more complex than it needs to be also suggests that the primordial soup where life began on earth was hot and not cold, as many scientists believe.
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The University of Bath researchers suggest that the primordial ‘doublet’ code was read in threes – but with only either the first two ‘prefix’ or last two ‘suffix’ pairs of bases being actively read.

The University of Bath researchers suggest that the primordial ‘doublet’ code was read in threes – but with only either the first two ‘prefix’ or last two ‘suffix’ pairs of bases being actively read.

By combining arrangements of these doublet codes together, the scientists can replicate the table of amino acids – explaining why some amino acids can be translated from groups of 2, 4 or 6 codons. They can also show how the groups of water loving (hydrophilic) and water-hating (hydrophobic) amino acids emerge naturally in the table, evolving from overlapping ‘prefix’ and ‘suffix’ codons.
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The theory also explains how the structure of the genetic code maximises error tolerance. For instance, ‘slippage’ in the translation process tends to produce another amino acid with the same characteristics, and explains why the DNA code is so good at maintaining its integrity.

“This is important because these kinds of mistakes can be fatal for an organism,” said Dr van den Elsen. “None of the older theories can explain how this error tolerant structure might have arisen.”

200,000 science and engineering doctorates in China by 2010?

Below are more statistics on engineering doctoral students in China, via China will increase its science and engineering doctorates to some 200,000 by 2010. I can’t say how reliable these figures are; but you can judge for yourself. The internet makes a great deal of information available but people still have to decide what level of credibility to give any source.

For more details see the original post:

Below are some figures taken from the China Statistical Yearbook 2005 on China’s graduate schools:

Science:
New enrollment: 41,607
Ph. D. 10,083
M. S. 30,984

Total enrollment: 102,769
Ph. D. 28,769
M. S. 73,612

Graduates: 17,540
Ph. D. 4,518
M. S. 13,022

Engineering:
New enrollment: 120,750
Ph. D. 20,271
M. S. 100,479

Total enrollment: 318,063
Ph. D. 69,315
M. S. 248,748

Graduates: 56,074
Ph. D. 8,054
M. S. 48,020
…
Number of science and engineering doctorate holders up to 1985:
Probably less than 2,000.
Number of science and engineering doctorate recipients between 1985 and 2001:
Approximately 51,400
Number of science and engineering doctorate recipients for 2002 and 2003:
Approximately 16,000.
Number of science and engineering doctorate recipients in 2004:
Exactly 12,572
Number of science and engineering doctorate recipients in 2005:
Approximately 15,000
Total number of science and engineering doctorates up to the end of 2005:
Approximately: 95,000
Total number of science and engineering doctorate enrollment at the beginning of 2006:
Approximately 85512

Whatever numbers turn out to be true the increase in science and engineering education in China is huge.