Tag Archives: cool

Car Powered Using Compressed Air

car powered using compressed air

Jules Verne predicted cars would run on air. The Air Car (link broken, so it was removed) is making that a reality. The car is powered by compressed air which certainly seems like an interesting idea. Air car ready for production (link broken, so it was removed, sigh, when will site stop failing the web so badly?):

Refueling is simple and will only take a few minutes. That is, if you live nearby a gas station with custom air compressor units. The cost of a fill up is approximately $2.00. If a driver doesn’t have access to a compressor station, they will be able to plug into the electrical grid and use the car’s built-in compressor to refill the tank in about 4 hours.

The car is said to have a driving range of 125 miles so by my calculation it would cost about 1.6 cents per mile. A car that gets 31 mpg would use 4 gallons to go 124 miles. At $3 a gallon for gas, the cost is $12 for fuel or about 9.7 cents per mile. I didn’t notice anything about maintenance costs. I don’t see any reason why the Air Car would cost more to maintain than a normal car.

The air car was named one of Time magazine’s best inventions of the 2007.

Five-seat concept car runs on air

An engineer has promised that within a year he will start selling a car that runs on compressed air, producing no emissions at all in town. The OneCAT will be a five-seater with a fibre-glass body, weighing just 350kg and could cost just over Â£2,500.
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Tata is the only big firm he’ll license to sell the car – and they are limited to India. For the rest of the world he hopes to persuade hundreds of investors to set up their own factories, making the car from 80% locally-sourced materials.
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“Imagine we will be able to save all those components traveling the world and all those transporters.” He wants each local factory to sell its own cars to cut out the middle man and he aims for 1% of global sales – about 680,000 per year. Terry Spall from the Institution of Mechanical Engineers says: “I really hope he succeeds. It is a really brave experiment in producing a sustainable car.”

Virus Engineered To Kill Deadly Brain Tumors

Yale Lab Engineers Virus That Can Kill Deadly Brain Tumors

A laboratory-engineered virus that can find its way through the vascular system and kill deadly brain tumors has been developed by Yale School of Medicine researchers, it was reported this week in the Journal of Neuroscience.

Each year 200,000 people in the United States are diagnosed with a brain tumor, and metastatic tumors and glioblastomas make up a large part of these tumors. There currently is no cure for these types of tumors, and they generally result in death within months.
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“Three days after inoculation, the tumors were completely or almost completely infected with the virus and the tumor cells were dying or dead,” van den Pol said. “We were able to target different types of cancer cells. Within the same time frame, normal mouse brain cells or normal human brain cells transplanted into mice were spared. This underlines the virus’ potential therapeutic value against multiple types of brain cancers.”

Pretty cool. Too bad these press releases never quite live up to the initial promise. Still this one is very cool, if it can succeed in helping even a small percentage of people it will be a great breakthrough. It is also just cool – using a virus to kill tumors – how cool is that?

Parasite Rex

Parasite Rex is a great book by Carl Zimmer (one of the bloggers listed in the Curious Cat directory of science blogs). This is the first book read as part of my specific plan to read more about bacteria, cells, virus, genes and the like.

One of the most enjoyable aspects of writing this blog is that I have focused much more on cool things I read. And over time the amazing things I posted about related to these topics made me realize I should put some focused effort to reading more on these topics. Some of the posts that sparked that idea: Tracking the Ecosystem Within Us – Inner Life of a Cell: Full Version – Where Bacteria Get Their Genes, People Have More Bacterial Cells than Human Cells, Biological Molecular Motors – Energy Efficiency of Digestion – Old Viruses Resurrected Through DNA – Midichloria mitochondrii – Microbes – Using Bacteria to Carry Nanoparticles Into Cells – How Bacteria Nearly Destroyed All Life – New Understanding of Human DNA – Soil Could Shed Light on Antibiotic Resistance – Symbiotic relationship between ants and bacteria

Parasite Rex was a great place to start. Carl Zimmer is a great writer, and the details on how many parasites there are and how interconnected those parasites are to living systems and how that has affected, and is affecting, us is amazing. And the next book I am reading is also fantastic: Good Germs, Bad Germs. Here is one small example from Parasite Rex, page 196-7:

A person who dies of sickle cell anemia is less likely to pass on the defective gene, and that means the disease should be exceedingly rare. But it’s not – one in four hundred American blacks has sickle sell anemia, and one in ten carries a single copy of the defective gene. The only reason the gene stays in such high circulation is that is also happens to be a defense against malaria.

Malaria is a parasite. One of the amazing things with repeated examples in the book were parasites that seemed to have extremely complicated life cycles (that don’t seem like a great strategy to prosper but obviously work). Where they grow in one life form (an insect or mammal or whatever) but must leave that life form for some other specific life form for the next stage in life (they cannot have descendants without doing so…). Seems like a crazy way to evolve but it happens over and over again.
Continue reading →

People Have More Bacterial Cells than Human Cells

Humans Carry More Bacterial Cells than Human Ones

All the bacteria living inside you would fill a half-gallon jug; there are 10 times more bacterial cells in your body than human cells
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The infestation begins at birth: Babies ingest mouthfuls of bacteria during birthing and pick up plenty more from their mother’s skin and milk—during breast-feeding, the mammary glands become colonized with bacteria. “Our interaction with our mother is the biggest burst of microbes that we get,”
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there are estimated to be more than 500 species living at any one time in an adult intestine, the majority belong to two phyla, the Firmicutes (which include Streptococcus, Clostridium and Staphylococcus), and the Bacteroidetes (which include Flavobacterium).
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probiotics – dietary supplements containing potentially beneficial microbes – have been shown to boost immunity. Not only do gut bacteria “help protect against other disease-causing bacteria that might come from your food and water,” Huffnagle says, “they truly represent another arm of the immune system.”
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But the bacterial body has made another contribution to our humanity – genes. Soon after the Human Genome Project published its preliminary results in 2001, a group of scientists announced that a handful of human genes – the consensus today is around 40 – appear to be bacterial in origin.

How cool is science? Very, I think 🙂

Nanotechnology Breakthroughs for Computer Chips

Nano On Off Switch

Photo: Actual scanning tunneling microscopy images of the naphthalocyanine molecule in the “on” and the “off” state. More images

IBM Unveils Two Major Nanotechnology Breakthroughs as Building Blocks for Atomic Structures and Devices

IBM scientists have made major progress in probing a property called magnetic anisotropy in individual atoms. This fundamental measurement has important technological consequences because it determines an atom’s ability to store information. Previously, nobody had been able to measure the magnetic anisotropy of a single atom.

With further work it may be possible to build structures consisting of small clusters of atoms, or even individual atoms, that could reliably store magnetic information. Such a storage capability would enable nearly 30,000 feature length movies or the entire contents of YouTube – millions of videos estimated to be more than 1,000 trillion bits of data – to fit in a device the size of an iPod. Perhaps more importantly, the breakthrough could lead to new kinds of structures and devices that are so small they could be applied to entire new fields and disciplines beyond traditional computing.

In the second report, IBM researchers unveiled the first single-molecule switch that can operate flawlessly without disrupting the molecule’s outer frame — a significant step toward building computing elements at the molecular scale that are vastly smaller, faster and use less energy than today’s computer chips and memory devices.

In addition to switching within a single molecule, the researchers also demonstrated that atoms inside one molecule can be used to switch atoms in an adjacent molecule, representing a rudimentary logic element. This is made possible partly because the molecular framework is not disturbed.

Open Source 3-D Printing

3-D Fabrication Goes Open Source

Hod Lipson and Evan Malone of Cornell University have cooked-up a cheap DIY 3-D printer – the Fab@Home – that they believe could lead to the widespread use of fabrication machines by hobbyists and experimenters. Fabrication machines, or fabbers, operate on the same principle as inkjet printers, but instead of squirting out ink onto paper, they squirt plastic or other materials into three-dimensional shapes. Commercial systems average around $100,000, but you can build Cornell’s Fab@Home for about US$2,300 worth of off-the-shelf parts.

Open Source for LEGO Mindstorms

Lego Tribot

Open Source Firmware, Developer Kits for LEGOÂ® MINDSTORMSÂ®:

“Most often, innovation comes from the core community of users. Our ongoing commitment to enabling our fan base to personalize and enhance their MINDSTORMS experience has reached a new level with our decision to release the firmware for the NXT brick as open source,” said SÃ¸ren Lund, director of LEGO MINDSTORMS.

photo: Lego TriBot – a flexible 3-wheeled driving robot with sound, light, touch and ultrasonic sensors – see more details.

Cool Mechanical Simulation System

Cool device from MIT: A Shrewd Sketch Interpretation and Simulation Tool.

We aim to create a tool that allows the engineer to sketch a mechanical system as she would on paper, and then allows her to interact with the design as a mechanical system, for example by seeing a simulation of her drawing. We have built an early incarnation of such a tool, called ASSIST, which allows a user to sketch simple mechanical systems and see simulations of her drawings in a two-dimensional kinematic simulator.

via: Back to the Drawing Board

Energy Efficiency of Digestion

Why is Fecal Matter Brown?

The complex digestion process ensures that almost no useful energy goes unused. The average bowel movement is three parts water to one part solid matter. Bacteria make up 30 percent of the solid stuff. The same goes for indigestible foods like cellulose and extra fiber. The remaining 40 percent contains various inorganic wastes, fats and used-up body substances like red blood cells

Scientists Examine 100 Trillion Microbes in Human Feces:

Aiding the large intestine in this task are trillions of microbes that reside in the gut, where they help digest foods we would otherwise have to avoid. In this way the bugs contribute to our overall health.

Some of these tiny settlers are with us from birth, imparted from our mothers, while others gradually colonize our bodies as we grow. This microbial community is as diverse as any found in Earth’s seas or soils, numbering up to 100 trillion individuals and representing more than 1,000 different species.

Self-Assembling Cubes Could Deliver Medicine

Nanocubes photos

Tiny Self-Assembling Cubes Could Carry Medicine, Cell Therapy – News Release from Johns Hopkins (pdf format)

Details of photos: “Scanning electron microscopy images of image of (A) a hollow, open surfaced, biocontainer, and (B) a device loaded with glass microbeads. (C) Fluorescence microscopy images of a biocontainer loaded with cell-ECM-agarose with the cell viability stain, Calcein-AM. (D) Release of viable cells from the biocontainer.”

Johns Hopkins researchers have devised a self- assembling cube-shaped perforated container, no larger than a dust speck, that could serve as a delivery system for medications and cell therapy.

When the process is completed, they form a perforated cube. When the solution is cooled, the solder hardens again, and the containers remain in their box-like shape.

“To make sure it folds itself exactly into a cube, we have to engineer the hinges very precisely,” Gracias said. “The self-assembly technique allows us to make a large number of these microcontainers at the same time and at a relatively low cost.”

Gracias and his colleagues used micropipettes to insert into the cubes a suspension containing microbeads that are commonly used in cell therapy. The lab team showed that these beads could be released from the cubes through agitation. The researchers also inserted human cells, similar to the type used in medical therapy, into the cubes. A positive stain test showed that these cells remained alive in the microcontainers and could easily be released.

And they are “always on the lookout for exceptional and highly creative undergraduate, graduate students and post-doctoral candidates” – maybe you.