Tag Archives: government

NIH Punished Scientist Who Called for Open Records

NIH Punished Scientist Who Had Called for Open Records

The National Institutes of Health and some leading universities, such as Harvard and Stanford, have suffered black eyes this year because of revelations that researchers with federal grants failed to disclose secret payments that they took from pharmaceutical companies.

The NIH was warned about the dangers of the problem years ago by one of its own scientists, Ned Feder, who wrote letters to several publications suggesting that the agency require its grantees to publicly disclose money they earn from medical companies. Instead of heeding Dr. Feder’s advice, the agency punished him

Dr. Feder went on to suggest that “the NIH could require grantees to make public disclosures of their paid arrangements with pharmaceutical, investment, and other companies, as well as their ownership of stock and stock options, as a condition of having their medical research funded by the government.”

The agency formally reprimanded Dr. Feder for writing to Nature and identifying himself in the letter as an employee of the NIH. Dr. Feder protested the reprimand, and it was subsequently removed, without explanation.

“The NIH has shown no interest in reforming its policies unless they’re forced to do it,” said Dr. Feder, who is now staff scientist at the Project on Government Oversight.

Related: From Ghost Writing to Ghost Management in Medical JournalsLack of Medical Study IntegrityFunding Medical ResearchR&D Spending in USA Universities

Patent Gridlock is Blocking Developing Lifesaving Drugs

How patent gridlock is blocking the development of lifesaving drugs by Michael Heller, Forbes

Since a 1980 Supreme Court decision allowing patents on living organisms, 40,000 dna-related patents have been granted. Now picture a drug developer walking into an auditorium filled with dozens of owners of the biotech patents needed to create a potential lifesaving cure. Unless the drugmaker can strike a deal with every person in the room, the new drug won’t be developed.

Nicholas Naclerio, who used to head the BioChip Division at Motorola , told Scientific American, “If we want to make a medical diagnostic with 40 genes on it, and 20 companies hold patents on those genes, we may have a big problem.”

And it’s not just drugs we’re losing. Today anything high tech–banking, semiconductors, software, telecom–demands the assembly of innumerable patents. Innovation has moved on, but we’re stuck with old-style ownership that’s easy to fragment and hard to put together. This debacle’s only upside is that assembling fragmented property is one of the great entrepreneurial and political opportunities of our era.

This is a critical problem I have written about before. The broken patent system is a serious problem that needs to be fixed.

Related: The Effects of Patenting on SciencePatent Policy Harming USA, and the worldPatenting Life is a Bad IdeaThe Differences Between Culture and CodeInnovation and Creative CommonsThe Value of the Public DomainThe Patent System Needs to be Significantly ImprovedAre Software Patents Evil?

Protecting the Food Supply

A few weeks ago we posted about Tracking Down Tomato Troubles as another example of the challenges of scientific inquiry. Too often, in the rare instances that science is even discussed in the news, the presentation provides the illusion of simple obvious answers. Instead it is often a very confusing path until the answers are finally found (posts on scientific investigations in action). At which time it often seems obvious what was going on. But to get to the solutions we need dedicated and talented scientists to search for answers.

Now the CDC is saying tomatoes might not be the source of the salmonella after all: CDC investigates possible non-tomato salmonella sources.

Federal investigators retraced their steps Monday as suspicions mount that fresh unprocessed tomatoes aren’t necessarily causing the salmonella outbreak that has sickened hundreds across the USA.

Three weeks after the Food and Drug Administration warned consumers to avoid certain types of tomatoes linked to the salmonella outbreak, people are still falling ill, says Robert Tauxe with the Centers for Disease Control and Prevention. The latest numbers as of Monday afternoon were 851 cases, some of whom fell ill as recently as June 20, says Tauxe, deputy director of the CDC’s division of foodborne diseases.

The CDC launched a new round of interviews over the weekend. “We’re broadening the investigation to be sure it encompasses food items that are commonly consumed with tomatoes,” Tauxe says. If another food is found to be the culprit after tomatoes were recalled nationwide and the produce industry sustained losses of hundreds of millions of dollars, food safety experts say the public’s trust in the government’s ability to track foodborne illnesses will be shattered.

“It’s going to fundamentally rewrite how we do outbreak investigations in this country,” says Michael Osterholm of the Center for Infectious Disease Research and Policy at the University of Minnesota. “We can’t let this investigation, however it might turn out, end with just the answer of ‘What caused it?’ We need to take a very in-depth look at foodborne disease investigation as we do it today.”

I am inclined to believe the FDA is not enough focused on food safety. Perhaps we are not funding it enough, but we sure are spending tons of money on something so I can’t believe more money needs to be spent. Maybe just fewer bills passed (that the politicians don’t even bother to read) with favors to special interests instead of funding to support science and food safety. Or perhaps we are funding enough (though I am skeptical of this contention) and we just are not allowing food safety to get in the way of what special interests want (so we fund plenty for FDA to have managed this much better, to have systems in place that would provide better evidence but they are either prevented from doing so or failed to do so). I am inclined to believe special interests have more sway in agencies like (NASA, EPA, FDA…) than the public good and scientific openness – which is very sad. And, it seems to me, politicians have overwhelmingly chosen not to support more science in places like FDA, CDC, NIH… while increasing federal spending in other areas dramatically.

Related: USDA’s failure to protect the food supplyFDA May Make Decision That Will Speed Antibiotic Drug ResistanceFood safety proposal: throw the bums outThe A to Z Guide to Political Interference in Science

Saving Fermilab

Fermilab was once the premiere particle physics research lab. It is still a very important research lab. But, I have said before, other countries are the ones making the larger efforts lately to invest in science and technology centers of excellence that the US was making in the 1960’s and 1970’s: Economic Strength Through Technology Leadership, Investing in Technology Excellence, etc..

I have also said that the past success of the US has left it in a still very strong position. For example, the anonymous donor that saved Fermilab with a $5 million donation likely benefited from the successful investments in science centers of excellence in the past (few countries – maybe 30, can rely on large donations from wealthy individuals, to sustain centers of excellence and I don’t think any approach what the USA has now – Howard Hughes Medical Institute, Standford, MIT…).

Excellent post on the the saving of Fermilab, To the person who saved Fermilab: Thank You.:

The facility has recently seen financial difficulties which have resulted in the layoffs of research staff and dramatic cuts in experiments. The world class research facility has been left to scrape together funds to pay the bills and has even had to auction off equipment and ask staff members to take pay cuts just to keep the lights on in the laboratories.

Fermilab also has an illustrious history of achievements in the field of supercomputer development and parallel processing. Fermilab has been on the forefront of applying supercomputing to physics research and is one of the top supercomputing centers of the world. Fermilab has claimed the world’s most powerful supercomputer on multiple occasions – although the title is rarely held long by any system due to the continuous advancements in computing. In recent years, Fermilab has been a leader in the development of “lattice” supercomputing systems and has developed methods for efficiently utilizing the power of multiple supercomputers in different locations through more [efficient] distribution practices.

To some, the construction of the Large Hadron Collider at CERN may seem to reduce the importance of Fermilab’s capabilities, but this is not at all the case. Although the LHC may take the title for the overall size and energy levels of a particle accelerator, Fermilab remains a uniquely capable particle physics research institution. Though less powerful, the Tevatron is able to operate for longer periods of time than the LHC and will likely require less downtime for maintenance, allowing for greater access and numerous types of research activities.

Related: CERN Pressure Test Failureposts on funding science researchMatter to Anti-Matter 3 Trillion Times a SecondGoogle Investing Huge Sums in Renewable EnergyGates Foundation and Rotary Pledge $200 Million to Fight PolioWashington WasteWashington Paying Out Money it Doesn’t HaveProposal to Triple NSF GFRP Awards and the Size of the Awards by 33%

Quake Lake Danger

Quakes lakes risk ‘slurry tsunami’

This month’s 7.9 magnitude tremor spawned 34 so-called quake lakes, according to the International Association of Hydraulic Engineering and Research expert. The vast pools of water were created when the earthquake triggered landslides down plunging valleys, clogging rivers and turning them into fast-rising lakes. Twenty-eight quake lakes are at risk of bursting, according to Chinese state media agency Xinhua. But the one at Tangjiashan – on the Jianjiang river above the town of Beichuan – is the most precarious.

The delicate, tortuous work involves heavy machinery gingerly shifting debris from the dam, and engineers blasting dynamite to carefully punch holes in the mountain of rubble and soil – although experts warn this risks further destabilising the structure. Nearly 160,000 people in the disaster zone have already been evacuated in case the Tangjiashan quake lake bursts.

Troops and engineers are racing to carve a 500 metre (1,640 ft) channel out of the landscape and divert the water towards the Fujiang river. They aim to complete the giant sluice and begin draining the 300 million cubic metre capacity lake within 10 days. “Once the water begins to flow over the top of the dam there’s nothing you can do to stop it,” said Dr Alex Densmore, of Durham University’s Institute of Hazard and Risk Research.

Little wonder then that Premier Wen Jiabao says he regards draining the swelling quake lakes at China’s ground zero as the nation’s most urgent task.

Related: Quake Lifts Island Ten Feet Out of OceanCivil Engineers: USA Infrastructure Needs ImprovementChina’s Technology Savvy LeadershipMegaflood Created the English Channel

Solar Thermal in Desert, to Beat Coal by 2020

Google, Chevron Build Mirrors in Desert to Beat Coal With Solar

Along a dusty two-lane highway in California’s Mojave Desert, 550,000 mirrors point skyward to make steam for electricity. Google Inc., Chevron Corp. and Goldman Sachs Group Inc. are betting this energy will become cheaper than coal.

The 1,000-acre plant uses concentrated sunlight to generate power for as many as 112,500 homes in Southern California. Rising natural gas prices and emissions limits may make solar thermal the fastest-growing energy source in the next decade, say backers including Vinod Khosla, the founder of computer maker Sun Microsystems Inc. Costs for the technology will fall below coal as soon as 2020, the U.S. government estimates.

“Solar thermal can provide a substantial amount of our power, more than 50 percent,” says Khosla

Nine solar thermal plants built in the California desert from 1985 to 1991 still operate, with Juno Beach, Florida-based FPL Group Inc. running seven. They have combined capacity of 354 megawatts, enough to power 230,000 Southern California homes. Development slowed when Congress eliminated tax credits for alternative energy in the early 1990s. Laws put in place in 2005 give solar investors a 30 percent tax credit.

Great progress is being made adding wind and solar capacity. And the increasing oil prices are encouraging much faster adoption of these technologies. The promise of widespread adoption is rapidly becoming a reality.

Related: Solar Energy: Economics, Government and TechnologyWind Power Potential to Produce 20% of Electricity Supply by 2030Google Investing Huge Sums in Renewable EnergySolar Tower Power Generation

Germany Bans Chemicals Linked to Bee Deaths

Germany bans chemicals linked to honeybee devastation

Germany has banned a family of pesticides that are blamed for the deaths of millions of honeybees. The German Federal Office of Consumer Protection and Food Safety (BVL) has suspended the registration for eight pesticide seed treatment products used in rapeseed oil and sweetcorn.

The move follows reports from German beekeepers in the Baden-Württemberg region that two thirds of their bees died earlier this month following the application of a pesticide called clothianidin. “It’s a real bee emergency,” said Manfred Hederer, president of the German Professional Beekeepers’ Association. “50-60% of the bees have died on average and some beekeepers have lost all their hives.” Tests on dead bees showed that 99% of those examined had a build-up of clothianidin.

The company says an application error by the seed company which failed to use the glue-like substance that sticks the pesticide to the seed, led to the chemical getting into the air.

Related: The Study of Bee Colony Collapses ContinuesBye Bye BeesScientists Search for Clues To Bee Mystery

USA Science Losing Ground

I have written about the continued decline in the relative position of science in the USA compared to the rest of the world: Engineering the Future EconomyEconomic Strength Through Technology LeadershipThe Best Research UniversitiesU.S. Slipping on ScienceDiplomacy and Science ResearchScientists and Engineers in Congress. The USA continues to act as though the rewards for scientific excellence automatically go to the USA. That isn’t the case and as many other countries make smart investments in scientific centers of excellence the USA chooses to do very little.

Has U.S. Science Lost Its Competitive Edge?

Craig Barrett, former CEO of Intel, delivered perhaps the most stinging indictment of the current political system. “There will be winners and losers, and the losers are the ones who insist on looking backwards,” said Barrett. “We continue to subsidize 19th century technology–like in the $290 billion farm bill–rather than the 21st century technologies that will allow us to remain competitive. We’re fat, dumb, and happy.”

hefty increases at three science agencies–the National Science Foundation, the Department of Energy Office of Science, and the National Institute of Standards and Technology. Last summer, legislation that incorporates many of those recommendations became law. But funding for most of the initiatives has yet to materialize.

Speakers repeatedly pointed to those anemic budgets as evidence that politicians haven’t realized the threats to American preeminence in science posed by the rest of the world.

As I have said many times the consequences of failing to take sensible action today will be large. Science and engineering centers of excellence have been a very important factor in the economic success of the USA.

Wind Power Potential to Produce 20% of Electricity Supply by 2030

Wind energy has been growing tremendously. In 2000 there were 2,500 megawatts (MW) of installed wind capacity in the United States. By the end of 2007, the U.S. installed capacity exceeded 16,000. A recent Department of Energy report sees the potential to provide up to 20% of our nation’s electrical supply via wind power by 2030.

Related: Global Wind Power Installed CapacityElectricity SavingsGoogle Investing Huge Sums in Renewable Energy

Running Out of Fish

I have posted before about the overfishing problems: Fishless FutureSelFISHingChinook Salmon Vanish Without a Trace. Here is an emotional article on the problem – How the world’s oceans are running out of fish

Ninety years of industrial-scale exploitation of fish has, he and most scientists agree, led to ‘ecological meltdown’. Whole biological food chains have been destroyed.

In 2002, the year an EU report revealed that the Senegalese fish biomass had declined 75 per cent in 15 years, Brussels bought rights for four years’ fishing of tuna and bottom-dwelling fish on the Senegal coasts, for just $4m a year. In 2006, access for 43 giant EU factory fishing vessels to Mauritania’s long coastline was bought for £24.3m a year. It’s estimated that these deals have put 400,000 west African fishermen out of work; some of them now take to the sea only as ferrymen for desperate would-be migrants to the Canary Islands and Europe.

Protecting up to 40 per cent of the world’s oceans in permanent refuges would enable the recovery of fish stocks and help replenish surrounding fisheries. ‘The cost, according to a 2004 survey, would be between £7bn and £8.2bn a year, after set-up. But put that against the £17.6bn a year we currently spend on harmful subsidies that encourage overfishing.’

The Newfoundland cod fishery, for 500 years the world’s greatest, was exhausted and closed in 1992, and there’s still no evidence of any return of the fish. Once stocks dip below a certain critical level, the scientists believe, they can never recover because the entire eco-system has changed.