Tag Archives: Science

New Discovery Finds Fungi Different From All Known Forms is Ubiquitous

A New, Somewhat Moldy Branch On The Tree Of Life

Many fungi are already familiar. There are mushrooms, yeasts, molds like the one that makes penicillin, plant diseases such as rusts and smuts. Mildew in your shower is one, along with athlete’s foot. There are even fungi that infect insects — as well as fungi that live on other fungi.

Biologists figure they’ve probably only cataloged about 10 percent of all fungal species. But they thought they at least knew all of the major groups.
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They found novel bits of DNA — related to fungi, but clearly different from all of the known varieties — just about everywhere, “including pond water, lake water, freshwater sediments and marine sediments,” Richards says. “Almost everywhere we looked we found this novel group.”

They then brought samples back to the lab and devised a technique to make the organisms containing this novel DNA glow under a microscope. As a result, they’ve managed to get a few glimpses of these mysterious life forms, which they have named cryptomycota.

“We know they have at least three stages to their life cycle,” Richards says. “One is where they attach to a host, which are photosynthetic algae. Another stage … they form swimming tails so they can presumably find food. And [there’s] another stage, which we call the cyst phase, where they go to sleep.”

Science continues to explore and find new wonders around us. There is so much still to learn.

Google Science Fair 2011 Projects

The Google Science Fair selected 60 semi-finalists in 3 groups (age 13-14, 15-16 and 17-18). The 60 global semi finalists will then be narrowed down by our judging panel to 15 global finalists who will be announced later in May.

The 15 global finalists will be flown to Google HQ in California, USA for our celebratory Science Fair event and finalist judging round will take place on 11 July 2011. These finalists will be expected to present their projects before a panel of acclaimed scientists including Nobel Laureates, tech visionaries and household names.

Sailboats using canting keels are among the world’s fastest ocean-going vessels; however, there are inherent problems. Canting sailboats require the addition of canards or dagger boards to replace the loss of the primary underwater lifting surface, adding significant complexity. The second and more important issue is that the cantilevered weight of the ballast bulb at the end of the keel generates tremendous loads on the vessel. The objective of this research was to test a concept to make sailboats even faster and safer than the current designs. To test the concept, this researcher built a remote control functional model fitted for both canting and hydrodynamic keels. The results showed that the hydrodynamic keel out performs the canting keel both upwind and downwind.

The Grand Prize winner plus one parent or guardian per winner will win an amazing 10 day trip to the Galapagos Islands with National Geographic Expeditions. Traveling aboard the National Geographic Endeavour the winner will visit Darwin’s living laboratory and experience up-close encounters with unique species such as flightless cormorants, marine iguanas, and domed giant tortoises. They also win a $50,000 scholarship, split equally between team members should a team win this prize. This scholarship is intended to be used towards the finalists’ further education.

The 2 age group winners that are not selected as the grand prize winner will win $25,000 scholarships.

You can vote on your favorite projects and help select the people’s choice winner that will receive a $10,000 scholarship.

5% of the Universe is Normal Matter, What About the Other 95%?

Dark Matters from PHD Comics on Vimeo.

Great discussion and illustration of the state of our understanding of physics, matter, dark matter and the rest of the stuff our universe has from PhD comics. What is the universe made of? 5% of it is normal matter (the stardust we are made of), 20% dark matter and the other 75% – we have no idea!

Dark Cosmos is a nice book on some of these ideas. It is 5 years old so missing some of the latest discoveries.

The Architecture of Access to Scientific Knowledge

The Architecture of Access to Scientific Knowledge from lessig on Vimeo.

Larry Lessig speaks at CERN about the proper use of copyright and the moral case for open access. As I have written many times, I strongly believe our society is better off when science is open. I believe we now are allowing a few greedy institution (that seek to restrict science for the benefit of their organization) to pay our politicians to damage society for the benefit of a few donors.

Quixperito – New Social Bookmarking Site

I have created a new social bookmarking site. The site is meant to highlight good content online and is moderated to remove low value and spam content. By developing a community of users that share interests in worthwhile content on a variety of topics I hope to create a useful resource for people.

The topics included now are limited to help focus on high value content and develop a community of users around various topics. Please join and participate. Without a community the value of the site is low. Currently there is a technology section that will be of interest to readers of this Curious Cat Science and Engineering Blog.

Other sections include: science, investing and business.

If you are interested in helping build the community please join and participate. You can post your related articles and posts and find new readers for your content. And by voting on others posts you can help highlight posts that the community finds worth reading.

Image of Map Showing Concentration of Life in Oceans

This image shows the abundance of life in the sea, measured by the SeaWiFS instrument aboard the Seastar satellite. Dark blue represents warmer areas where there is little life due to lack of nutrients, and greens and reds represent cooler nutrient-rich areas.

The nutrient-rich areas include coastal regions where cold water rises from the sea floor bringing nutrients along and areas at the mouths of rivers where the rivers have brought nutrients into the ocean from the land. NASA has posted a large gallery of great images for Earth Day.

Cancer Vaccines

A reader commented on a previous post (MIT Engineers Design New Type of Nanoparticle for Vacines) asking about how vaccines can fight cancer. Preventative vaccines can build up immune response to viruses which cause cancer. So the vaccine actually works against the virus which prevents the virus from causing cancer.

The U.S. Food and Drug Administration (FDA) has approved two vaccines, GardasilÂ® and CervarixÂ®, that protect against infection by the two types of human papillomavirus (HPV) – types 16 and 18 – that cause approximately 70% of all cases of cervical cancer worldwide. At least 17 other types of HPV are responsible for the remaining 30% of cervical cancer cases. HPV types 16 and/or 18 also cause some vaginal, vulvar, anal, penile, and oropharyngeal cancers.

Many scientists believe that microbes cause or contribute to between 15% and 25% of all cancers diagnosed worldwide each year, with the percentages being lower in developed than developing countries.

Vaccines can also help stimulate the immune system to fight cancers.

B cells make antibodies, which are large secreted proteins that bind to, inactivate, and help destroy foreign invaders or abnormal cells. Most preventive vaccines, including those aimed at hepatitis B virus (HBV) and human papillomavirus (HPV), stimulate the production of antibodies that bind to specific, targeted microbes and block their ability to cause infection. Cytotoxic T cells, which are also known as killer T cells, kill infected or abnormal cells by releasing toxic chemicals or by prompting the cells to self-destruct (a process known as apoptosis).

Other types of lymphocytes and leukocytes play supporting roles to ensure that B cells and killer T cells do their jobs effectively. These supporting cells include helper T cells and dendritic cells, which help activate killer T cells and enable them to recognize specific threats.

Cancer treatment vaccines are designed to work by activating B cells and killer T cells and directing them to recognize and act against specific types of cancer. They do this by introducing one or more molecules known as antigens into the body, usually by injection. An antigen is a substance that stimulates a specific immune response. An antigen can be a protein or another type of molecule found on the surface of or inside a cell.

Gravity and the Scientific Method

One of the topics I return to repeatedly is the scientific method – theories must to tested. As evidence mounts that new ideas do a good job of explaining theories they become more accepted. But they continue to be tested in new ways as the ideas are extended and ramification are explored. And science progress means that old conventions can be overturned as new evidence is gathered.

Science is not about current beliefs. Science is about seeking knowledge. If the search for knowledge leads to evidence that old ideas were wrong those ideas are overturned. Since people are involved that process isn’t as clean as it sounds above. People get comfortable with beliefs. They build careers on expanding those beliefs. Most are uncomfortable when they are challenged and don’t accept new ideas even when the evidence mounts. But some do accept the new ideas. Some challenge the new ideas by running experiments. And some of those prove the new ideas faulty. Some become convinced of the new ideas as the results of their experiments make the new ideas seem more sensible (instead of getting the results they expected).

Building the body of scientific knowledge is not nearly as clean and simple as most people think. It isn’t a simple process, what is the underlying truth can be debatable. But the beauty of the scientific process is how it helps us overcome our biases and provide evidence to support the theories we support. The scientific method (combined with our human involvement) doesn’t mean new ideas are accepted easily but it does mean new ideas compete on the basis of evidence not just the power of those that hold the beliefs.

Is gravity not actually a force? Forcing theory to meet experiments
Continue reading →

How To Make Your Own Pesticide with Ingredients from Your Kitchen

Video by the Singapore National Park Board, on creating your own pesticide with just water, dish-washing liquid, chili, garlic and cooking oil.

Cat Allergy Vaccine Created

McMaster University researchers have developed aÂ vaccine which successfully treats people with anÂ allergy to cats. Traditionally, frequent allergy shots have been considered the most effective way to bring relief — other than getting rid of the family pet — for the 8 to 10% of the population allergic to cats.

Both options, may now be avoided thanks to the work of immunologistÂ Mark LarchÃ©, professor at theÂ Michael G. DeGroote School of Medicine andÂ Canada Research Chair in Allergy & Immune Tolerance.

Building on research he’s conducted for the past 10 years in Canada and Britain, LarchÃ© and his research team have developed a vaccine which is effective and safe with almost no side effects. The research is published in a the January 2011 issue of theÂ Journal of Allergy & Clinical Immunology, a leading journal in the allergy field.

The researchers took one protein (molecule) that cats secrete on their fur which causes the majority of allergic problems. Using blood samples from 100 patient volunteers allergic to cats, they deconstructed the molecule and identified short regions within the protein which activate T-cells (helper cells that fight infection) in the immune system.

Using the amino acid code for the whole protein, researchers made synthetic versions of these regions. For the cat allergy vaccine, they found seven peptides (strings of amino acids). “And those synthetic peptides are what we mix together to make the vaccine,” said LarchÃ©. “We picked the peptides that would work in as much of the population as possible.”

Known as “peptide immunotherapy,” a low dose of the vaccine is given into the skin. Initially, four to eight doses a year may be required, but the side effects of the traditional allergy shots do not arise, LarchÃ© said. The optimal dose will be determined in phase three clinical trials which are getting underway with a much larger group of cat allergy sufferers.

The development of a vaccine to treat people allergic to cats is the first in a line of vaccines developed withÂ Adiga Life Sciences, a company established at McMaster in 2008. It is a joint venture between McMaster University Circassia Ltd., a UK-based biotech company.

Adiga and McMaster are now collaborating on research into the use of peptide immunotherapy for house dust mite, ragweed, grass, birch tree and moulds