Tag Archives: scientific literacy

Science Explained: RNA Interference

Explained: RNA interference

Every high school biology student learns the basics of how genes are expressed: DNA, the cell’s master information keeper, is copied into messenger RNA, which carries protein-building instructions to the ribosome, the part of the cell where proteins are assembled.

But it turns out the picture is far more complicated than that. In recent years, biologists have discovered a myriad of other molecules that fine-tune this process, including several types of RNA (ribonucleic acid). Through a naturally occurring phenomenon known as RNA interference, short strands of RNA can selectively intercept and destroy messenger RNA before it delivers its instructions.

Double-stranded RNA molecules called siRNA (short interfering RNA) bind to complementary messenger RNA, then enlist the help of proteins, the RNA-induced silencing complex. Those proteins cleave the chemical bonds holding messenger RNA together and prevent it from delivering its protein-building instructions.

This article from MIT is one, of many, showing MIT’s commitment to science education of the public. Good job, MIT.

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Test it Out, Experiment by They Might Be Giants

Put It to the Test is one of the songs on the great new Album and animated DVD from They Might Be Giants: Here Comes Science.

Are you sure that thing is true, or did someone just tell it to you.
Come up with a test. Test it out.
Find a way to show what would happen if you were incorrect. Test it out.
A fact is just a fantasy unless it can be checked.
Make a test. Test it out.

A fun song on fundamentals of experimenting to the scientific method.

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Neil Degrasse Tyson: Scientifically Literate See a Different World

From the interview of Neil Degrasse Tyson from 3 July 2009.

“If you are scientifically literate the world looks very different to you. Its not just a lot of mysterious things happening. There is a lot we understand out there. And that understanding empowers you to, first, not be taken advantage of by others who do understand it. And second there are issues that confront society that have science as their foundation. If you are scientifically illiterate, in a way, you are disenfranchising yourself from the democratic process, and you don’t even know it.”

I agree, and, as I have said before, when a society allows a scientific illiteracy to continue then the potential for abuse by those that manipulate those that are scientifically illiterate leaves the society vulnerable to making very bad choices.

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Experimenting Social Network

Social media is definitely a fad filled with lots of ways to waste time. It also does have real value, ways to connect to things people care about and wish to focus on. Reddit is a good site for finding interesting resources online. Sub-reddits are topical areas within Reddit (I have set up management and investing sub-reddits). A new experiment subreddit looks very interesting:

Each experiment will go through a few threads. The first step will be a query for experimental methods. Someone will present a problem or piece of information they want to find out, and then others will suggest methods. Once this is agreed upon, it will be carried out, and a second thread will be posted detailing the method and providing a place to post results via the comments. Then, a third thread can be made to discuss the results. Having more than one thread for every experiment will make things more accessible and easier to sort.

Don’t research ways other people have experimentally determined these things. Submit original ideas to the experimental design thread. Try to come up with a novel way to discover things, but don’t be completely limited by this suggestion. This is chiefly about rediscovery, not repeating someone else’s experiment, but sometimes there’s fun and merit in that as well.

I have joined. You can go to Reddit and join this subreddit to see experiences with experimenting to learn about the world around us.

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What is a Molecule?

One of the things I keep meaning to do more of with this blog is provide some post on basic science concepts that may help raise scientific literacy. Some of these will be pretty obvious but even reminders on some facts you know can sometimes help.

What is a molecule?

A molecule is the smallest particle of a compound that has all the chemical properties of that compound. Molecules are made up of two or more atoms, either of the same element or of two or more different elements. The example of molecules are water (H2O) and carbon dioxide (CO2) and molecular nitrogen (N2).

Organic molecules contain Carbon, for example, Methane CH4). The original definition of “organic” chemistry came from the misconception that organic compounds were always related to life processes.

A few types of compounds such as carbonates, simple oxides of carbon and cyanides, as well as the allotropes of carbon, are considered inorganic. The division between “organic” and “inorganic” carbon compounds while “useful in organizing the vast subject of chemistry…is somewhat arbitrary”

Ionic compounds, such as common salt, are made up not of molecules, but of ions arranged in a crystalline structure. Unlike ions, molecules carry no net electrical charge.

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Science Knowledge Quiz

pew research science quiz results

Pew Research Center’s new study of science and its impact on society includes a science knowledge quiz. You can test yourself on the quiz. Thankfully I was able to get all 12 answers correct, which 10% of those taking the test have done. The median score was 8 out of 12.

I find some of the results surprising. The question most often answered correctly is “Which over-the-counter drug do doctors recommend that people take to help prevent heart attacks?”. The least often “Electrons are smaller than atoms,” a true or false question fewer than 50% of people got right.

Public Praises Science; Scientists Fault Public, Media

Americans like science. Overwhelming majorities say that science has had a positive effect on society and that science has made life easier for most people. Most also say that government investments in science, as well as engineering and technology, pay off in the long run. And scientists are very highly rated compared with members of other professions: Only members of the military and teachers are more likely to be viewed as contributing a lot to society’s well-being.

Just 17% of the public thinks that U.S. scientific achievements rate as the best in the world. A survey of more than 2,500 scientists, conducted in collaboration with the American Association for the Advancement of Science (AAAS), finds that nearly half (49%) rate U.S. scientific achievements as the best in the world.

large percentages think that government investments in basic scientific research (73%) and engineering and technology (74%) pay off in the long run. Notably, the partisan differences in these views are fairly modest, with 80% of Democrats and 68% of Republicans saying that government investments in basic science pay off in the long run. Comparable percentages of Democrats and Republicans say the same about government investments in engineering and technology.

In this regard, public views about whether funding for scientific research should be increased, decreased or kept the same have changed little since the start of the decade. Currently, more than twice as many people say that, if given the task of making up the budget for the federal government, they would increase (39%) rather than decrease (14%) funding for scientific research; 40% say they would keep spending as it is. That is largely unchanged from 2001, when 41% said they would increase funding for scientific research.

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Value of Prostate Cancer Screening Questioned by Two Studies

Ben Goldacre, in his bad science blog, again takes on journalist’s articles of health research in: Venal, misleading, pathetic, dangerous, stupid, and busted

1410 men would need to be screened to prevent one death. For each death prevented, 48 people would need to be treated: and prostate cancer treatment has a high risk of very serious side effects like impotence and incontinence. These figures are not hard to find: they are in the summary of the research paper.

For complex risk decisions like screening, it has been shown in three separate studies that patients, doctors, and NHS purchasing panels make more rational decisions about treatments and screening programmes when they are given the figures as real numbers, as I did above, instead of percentages. I’m not saying that PSA screening is either good or bad: I am saying that people deserve the figures in the clearest form possible so they can make their own mind up.

So newspapers ignore one half of the evidence, and they fail to explain the other half properly.

They can also link directly and transparently to scientific papers, which mainstream media still refuses to do. Journalists insist that we need professionals to mediate and explain science. From today’s story, their self belief seems truly laughable.

He also says some journalists got it right including the Washington Post in, Prostate Cancer Screening May Not Reduce Deaths:

The PSA blood test, which millions of men undergo each year, did not lower the death toll from the disease in the first decade of a U.S. government-funded study involving more than 76,000 men, researchers reported yesterday. The second study, released simultaneously, was a European trial involving more than 162,000 men that did find fewer deaths among those tested. But the reduction was relatively modest and the study showed that the tests resulted in a large number of men undergoing needless, often harmful treatment.

I think it is true that most people need help having science mediated to some extent. But he is also right that those doing so need to do better. And also everyone needs to learn about science to understand the choices they personally and politically (for policy issues) need to make decisions on. Being scientifically illiterate is dangerous.

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Nearly Half of Adults in the USA Don’t Know How Long it Takes the Earth to Circle the Sun

Questions:

  • How long does it take for the Earth to revolve around the Sun?
  • Did the earliest humans and dinosaurs live on the earth at the same time?
  • What percent of the Earth’s surface that is covered with water?

According to the national survey commissioned by the California Academy of Sciences: only 53% of adults know how long it takes for the Earth to revolve around the Sun; only 59% of adults know that the earliest humans and dinosaurs did not live at the same time; only 47% of adults can roughly approximate the percent of the Earth’s surface that is covered with water. Only 21% of adults answered all three questions correctly. I sure hope readers of this blog do much better than that.

Despite the fact that access to fresh water is likely to be one of the most pressing environmental issues over the coming years, less than 1% of U.S. adults know what percent of the planet’s water is fresh (the correct answer is 3%).

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Answers: Continue reading

Mental Pick-Me-Ups: The Coming Boom

I am not a fan of lifestyle drugs. People seem to forget that drugs have side effects that are quite large. Being surprised when a drug has adverse consequences shows a failure to understand the risks. You should assume adverse effects and take them only when that risk is outweighed by significant tangible benefits. A Boom in Memory-Enhancing Drugs?

A whole generation has come of age using attention-deficit drugs such as Adderall and Ritalin, a category valued at nearly $4.7 billion in 2007. A lot of teenagers have used them casually as study aids, often buying them on the Internet. And now, overworked professionals are seeing the appeal.

And when they almost certainly have significant adverse effects on many people, then people will get upset. Granted the drug companies pushing sales for negligible benefits do deserve condemnation. However, the larger problem is people that choose to risk their health as though they don’t have the ability to learn and can just ignore evidence of risks.

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Promoting Bio-Literacy

Wisconsin State Herbarium tries to ‘counteract bio-illiteracy’

“In a past century people could go outside and name the flowers or trees,” said Ken Cameron, the herbarium’s director. “Now you take a kid outside and the most they can say is, ‘It’s a tree.’ If we can get students in and get them excited, then I think we’ve helped to counteract bio-illiteracy.”

Herbaria are becoming more of a rarity. And the UW-Madison has the third largest collection of any public university in the country, behind the universities of California and Michigan. At many universities, botany has been absorbed into large biology departments, and collections put into storage. That has not happened at UW-Madison.

“The combination of having a botany department and a big herbarium is getting pretty rare,” said David Baum, botany department chairman. “And more and more herbaria are closing or making the decision to move off campus into storage, which has a real negative effect on research.”

The University of Wisconsin-Madison Herbarium, founded in 1849 (the year the University was founded), is a museum collection of dried, labeled plants of state, national and international importance, which is used extensively for taxonomic and ecological research, as well as for teaching and public service. It contains the world’s largest collection of Wisconsin plants, about one-third of its 1,000,000 specimens having been collected within the state. Most of the world’s floras are well represented, and the holdings from certain areas, such as the Upper Midwest, eastern North America and western Mexico, are widely recognized as resources of global significance.

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