Tag Archives: Technology

Apple’s iPad

Steve Jobs introduces the Apple iPad. A touch screen tablet with wireless internet connectivity and a touch screen keyboard (when desired).

Siftable Modular Computers

Pretty cool. I must admit I don’t really see how this would function outside of specifically designed situation. I can imagine it could be very cool for education, especially of young kids. Siftables act in concert to form a single interface: users physically manipulate them – piling, grouping, sorting – to interact with digital information and media. David Merrill and Jeevan Kalanithi originally created Siftables at the MIT Media Lab and have formed a company to commercialize the product and have received a grant from NSF to continue the work.

Arduino: Open Source Programmable Hardware

Arduino is an open-source electronics prototyping platform based on flexible, easy-to-use hardware and software. It’s intended for artists, designers, hobbyists, and anyone interested in creating interactive objects or environments.

Arduino can sense the environment by receiving input from a variety of sensors and can affect its surroundings by controlling lights, motors, and other actuators. The microcontroller on the board is programmed using the Arduino programming language and the Arduino development environment.

The boards can be built by hand or purchased preassembled; the software can be downloaded for free. The hardware reference designs (CAD files) are available under an open-source license, you are free to adapt them to your needs.

See the getting started guide to try for yourself.

Printing Bone, Muscle and More

A Pittsburgh-based research team has created and used an innovative ink-jet system to print “bio-ink” patterns that direct muscle-derived stem cells from adult mice to differentiate into both muscle cells and bone cells.

The custom-built ink-jet printer, developed at Carnegie Mellon’s Robotics Institute, can deposit and immobilize growth factors in virtually any design, pattern or concentration, laying down patterns on native extracellular matrix-coated slides (such as fibrin). These slides are then placed in culture dishes and topped with muscle-derived stem cells (MDSCs). Based on pattern, dose or factor printed by the ink-jet, the MDSCs can be directed to differentiate down various cell-fate differentiation pathways (e.g. bone- or muscle-like).

“This system provides an unprecedented means to engineer replacement tissues derived from muscle stem cells,” said Johnny Huard, professor of orthopedic surgery at the University of Pittsburgh School of Medicine and director of the Stem Cell Research Center at Children’s Hospital of UPMC. Huard has long-standing research findings that show how muscle-derived stem cells (MDSCs) from mice can repair muscle in a model for Duchenne Muscular Dystrophy, improve cardiac function following heart failure, and heal large bone and articular cartilage defects.

Weiss and Campbell, along with graduate student Eric Miller, previously demonstrated the use of ink-jet printing to pattern growth factor “bio-inks” to control cell fates. For their current research, they teamed with Phillippi, Huard and biologists of the Stem Cell Research Center at Children’s Hospital to gain experience in using growth factors to control differentiation in populations of MDSCs from mice.

The team envisions the ink-jet technology as potentially useful for engineering stem cell-based therapies for repairing defects where multiple tissues are involved, such as joints where bone, tendon, cartilage and muscle interface. Patients afflicted with conditions like osteoarthritis might benefit from these therapies, which incorporate the needs of multiple tissues and may improve post-treatment clinical outcomes.

The long-term promise of this new technology could be the tailoring of tissue-engineered regenerative therapies. In preparation for preclinical studies, the Pittsburgh researchers are combining the versatile ink-jet system with advanced real-time live cell image analysis developed at the Robotics Institute and Molecular Biosensor and Imaging Center to further understand how stem cells differentiate into bone, muscle and other cell types.

Bionic Vision

Micro Machines and Opto-Electronics on a Contact Lense

Fiction now meets reality with prototype contact lenses developed by Babak Parviz at the University of Washington, in Seattle. Dr. Parviz’s prototype lenses can be used as biosensors to display body chemistry or as a heads up display (HUD). Powered by radio waves and 330 microwatts of power from a loop antenna that picks up power beamed from nearby radio sources, future versions will also be able to harvest power from a cell phone.

In his early 2008 lab tests, rabbits safely wore contact lenses with metal connectors for electronic circuits. The prototype lenses contained an electric circuit as well as red light-emitting diodes for a display. The lenses were tested on rabbits for up to 20 minutes and the animals showed no adverse effects.
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Contact lenses as replacements for smart phone displays — even to monitor blood glucose levels — might best be done while not operating heavy equipment. “The true promise of this research is not just the actual system we end up making, whether it’s a display, a biosensor, or both,” comments Dr. Parviz. “We already see a future in which the humble contact lens becomes a real platform, like the iPhone is today, with lots of developers contributing their ideas and inventions. As far as we’re concerned, the possibilities extend as far as the eye can see, and beyond.”

Engineering: Cellphone Microscope

UCLA Professor Aydogan Ozcan‘s invention (LUCAS) enables rapid counting and imaging of cells without using any lenses even within a working cell phone device. He placed cells directly on the imaging sensor of a cell phone. The imaging sensor captures a holographic image of the cells containing more information than a conventional microscope. The CelloPhone received a Wireless Innovations Award from Vodafone

a wireless health monitoring technology that runs on a regular cell-phone would significantly impact the global fight against infectious diseases in resource poor settings such as in Africa, parts of India, South-East Asia and South America.

The CelloPhone Project aims to develop a transformative solution to these global challenges by providing a revolutionary optical imaging platform that will be used to specifically analyze bodily fluids within a regular cell phone. Through wide-spread use of this innovative technology, the health care services in the developing countries will significantly be improved making a real impact in the life quality and life expectancy of millions.
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For most bio-medical imaging applications, directly seeing the structure of the object is of paramount importance. This conventional way of thinking has been the driving motivation for the last few decades to build better microscopes with more powerful lenses or other advanced imaging apparatus. However, for imaging and monitoring of discrete particles such as cells or bacteria, there is a much better way of imaging that relies on detection of their shadow signatures. Technically, the shadow of a micro-object can be thought as a hologram that is based on interference of diffracted beams interacting with each cell. Quite contrary to the dark shadows that we are used to seeing in the macro-world (such as our own shadow on the wall), micro-scale shadows (or transmission holograms) contain an extremely rich source of quantified information regarding the spatial features of the micro-object of interest.

By making use of this new way of thinking, unlike conventional lens based imaging approaches, LUCAS does not utilize any lenses, microscope-objectives or other bulk optical components, and it can immediately monitor an ultra-large field of view by detecting the holographic shadow of cells or bacteria of interest on a chip. The holographic diffraction pattern of each cell, when imaged under special conditions, is extremely rich in terms of spatial information related to the state of the cell or bacteria. Through advanced signal processing tools that are running at a central computer station, the unique texture of these cell/bacteria holograms will enable highly specific and accurate medical diagnostics to be performed even in resource poor settings by utilizing the existing wireless networks.

This is another great example of engineers creating technologically appropriate solutions.

Low-Cost Multi-touch Whiteboard Using Wii Remote

Using infrared (IR) light pens and the Wii Remote, it is possible to create very low-cost multi-point interactive whiteboards and multi-point tablet displays. Johnny Chung Lee, Carnegie Mellon University. Download the software. Great stuff, it is wonderful to see what people can create with technology.

Car Style Mass Transit Mag Lev System

Skytran is a very cool sounding transportation option. It promises, individual transportation modules traveling at 100 miles per hour within the city nonstop to many more points than light rail can service. The current non-solutions we have been attempting for decades of building more and more roads is not working.

The costs is estimated at much cheaper than other alternatives. It would be great if something like this could actually make it (it is much easier to dream about possibilities than to bring them into the world).

From the SkyTran web site:

It works like a taxi that picks you up and drives you to your destination. You travel only with people you choose to, in personal-sized vehicles. The electric vehicles are automatically driven at a constant speed on the main guideway. Like on a freeway, you travel non-stop until taking an exit-ramp at your destination. Also like a freeway, instead of intersections PRT has over-passes so you truly never have to stop… vehicles are lined up waiting for you at boarding stations, and after you get out, they either line up to wait for another rider, or go park themselves and wait for peak periods when they’ll be needed.

At 60 mph the electricity for SkyTran would cost less than 1 cent per mile (at current electricity costs of 11 cents per kWhr). By comparison, buying gas for a 30-MPG car at $2/gallon costs more than 7 times as much.

The site estimates the cost at$10 million per mile for one-way track and $15 million per mile for two-way track. Fundamentally, SkyTran track can be cheaply built because all of the components are very light-weight. Weight is why roads and trains cost so much… In comparison, SkyTran’s guideway only needs to support one 1000 pound (loaded) vehicle at a time… See the detailed cost evaluation page.
Continue reading →

3D Printing is Here

photo of objects printed using a 3D printer

Photo by Jessica Sabo at the at 2009 Annual ASEE Conference.

The Future of Printing is 3D [I removed the broken link]

At this year’s annual ASEE Conference in Austin, one of the main topics of conversation started with the question, “have you seen the 3D printer?”. The company Stratasys, Inc. has created their Dimension 3D Printers. Their latest innovation is their line of uPrint machines, which are less costly (prices starting at $14,900)
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Jesse Roitenberg, the representative from Stratasys at the conference, explained the benefits of using 3D printing as opposed to building models by hand:

“With a 3D printer, you are actually able to create an object as you had designed it. Once the object is created, the designer is then able to hold, test and verify the design. The object created is more accurate and the process is less time consuming.”
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The Dimension 3D printers have been used in both educational facilities and the workplace, benefiting everyone from engineers to middle school science teachers. Below is a video of Jay Leno explaining how he was able to use the 3D printer to recreate an old steam engine car part.

Norman E. Borlaug 1914-2009

The Father Of the Green Revolution

Norman E. Borlaug, 95, an American plant pathologist who won the Nobel Peace Prize in 1970 for starting the “Green Revolution” that dramatically increased food production in developing nations and saved countless people from starvation, died Saturday at his home in Dallas.

“More than any other single person of this age, he has helped provide bread for a hungry world,” the Nobel committee said in honoring him. “Dr. Borlaug has introduced a dynamic factor into our assessment of the future and its potential.”
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In his lecture accepting the Nobel Prize, he said an adequate supply of food is “the first component of social justice. . . . Otherwise there will be no peace.”
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In 1977, Dr. Borlaug received the Medal of Freedom, the highest civilian honor of the U.S. government.

Billions Served: Norman Borlaug interviewed by Ronald Bailey

As a matter of fact, Mother Nature has crossed species barriers, and sometimes nature crosses barriers between genera–that is, between unrelated groups of species. Take the case of wheat. It is the result of a natural cross made by Mother Nature long before there was scientific man. Today’s modern red wheat variety is made up of three groups of seven chromosomes, and each of those three groups of seven chromosomes came from a different wild grass. First, Mother Nature crossed two of the grasses, and this cross became the durum wheats, which were the commercial grains of the first civilizations spanning from Sumeria until well into the Roman period. Then Mother Nature crossed that 14-chromosome durum wheat with another wild wheat grass to create what was essentially modern wheat at the time of the Roman Empire.

Durum wheat was OK for making flat Arab bread, but it didn’t have elastic gluten. The thing that makes modern wheat different from all of the other cereals is that it has two proteins that give it the doughy quality when it’s mixed with water. Durum wheats don’t have gluten, and that’s why we use them to make spaghetti today. The second cross of durum wheat with the other wild wheat produced a wheat whose dough could be fermented with yeast to produce a big loaf. So modern bread wheat is the result of crossing three species barriers, a kind of natural genetic engineering.
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I see no difference between the varieties carrying a BT gene or a herbicide resistance gene, or other genes that will come to be incorporated, and the varieties created by conventional plant breeding. I think the activists have blown the health risks of biotech all out of proportion.
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the data that’s put out by the World Health Organization and [the U.N.’s Food and Agriculture Organization], there are probably 800 million people who are undernourished in the world. So there’s still a lot of work to do.

I am a bit more cautious about supporting genetic engineering in our food supply but I agree with him that we need to remain focused on the lives of hundreds of millions of hungry people (which is far too often ignored). I am worried about the risks to the environment and human health. I am also worried about the concentration of food plants in a greatly reduced genetic varieties that are more productive in general but increase the risks of massive food failures (due to limited genetic varieties).