Tag Archives: university research

Robots That Start as Babies Master Walking Faster Than Those That Start as Adults

In a first-of-its-kind experiment, Bongard created both simulated and actual robots that, like tadpoles becoming frogs, change their body forms while learning how to walk. And, over generations, his simulated robots also evolved, spending less time in “infant” tadpole-like forms and more time in “adult” four-legged forms.

These evolving populations of robots were able to learn to walk more rapidly than ones with fixed body forms. And, in their final form, the changing robots had developed a more robust gait — better able to deal with, say, being knocked with a stick — than the ones that had learned to walk using upright legs from the beginning.

Bongard’s research, supported by the National Science Foundation, is part of a wider venture called evolutionary robotics. “We have an engineering goal,” he says “to produce robots as quickly and consistently as possible.” In this experimental case: upright four-legged robots that can move themselves to a light source without falling over.

Using a sophisticated computer simulation, Bongard unleashed a series of synthetic beasts that move about in a 3-dimensional space. “It looks like a modern video game,” he says. Each creature — or, rather, generations of the creatures — then run a software routine, called a genetic algorithm, that experiments with various motions until it develops a slither, shuffle, or walking gait — based on its body plan — that can get it to the light source without tipping over.

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Real Time Hologram Projection Getting Closer

A team led by the University of Arizona professor of Materials Science and Engineering Nasser Peyghambarian has developed a new type of holographic telepresence that allows the projection of a three-dimensional moving image without the need for special eyewear such as 3D glasses or other auxiliary devices.

“Holographic telepresence means we can record a three-dimensional image in one location and show it in another location, in real-time, anywhere in the world,” said Peyghambarian, who led the research effort.

“Holographic stereography has been capable of providing excellent resolution and depth reproduction on large-scale 3D static images,” the authors wrote, “but has been missing dynamic updating capability until now.”

The prototype device uses a 10-inch screen, but Peyghambarian’s group is already successfully testing a much larger version with a 17-inch screen. The image is recorded using an array of regular cameras, each of which views the object from a different perspective. The more cameras that are used, the more refined the final holographic presentation will appear.

Monarch Butterflies Use Medicinal Plants

Monarch butterflies eat toxic plants (that they have evolved to tolerate and make the butterflies themselves toxic to predators). They use medicinal plants to treat their offspring for disease, research by Emory biologists shows. When the butterflies are infected by certain parasites the butterflies have a strong preference to lay their eggs on a plant (tropical milkweed) that will help the caterpillar fight the parasite when it eats those leaves (it serves as a drug for them). Their experiments may be the best evidence to date that animals use medication.

Nearly 1 million Children Potentially Misdiagnosed with ADHD in the USA

Nearly 1 million children in the United States are potentially misdiagnosed with attention deficit hyperactivity disorder simply because they are the youngest – and most immature – in their kindergarten class, according to new research by , Todd Elder, a Michigan State University economist.

These children are significantly more likely than their older classmates to be prescribed behavior-modifying stimulants such as Ritalin, said Todd Elder, whose study will appear in a forthcoming issue of the Journal of Health Economics (closed science, unfortunately). Michigan State should stop funding closed journals with free content – other schools have decided to put science first, before supporting a few outdated business models of select journals.

Such inappropriate treatment is particularly worrisome because of the unknown impacts of long-term stimulant use on children’s health, Elder said. It also wastes an estimated $320 million-$500 million a year on unnecessary medication – some $80 million-$90 million of it paid by Medicaid, he said.

ADHD is the most commonly diagnosed behavioral disorder for kids in the United States, with at least 4.5 million diagnoses among children under age 18, according to the Centers for Disease Control and Prevention.

The youngest kindergartners were 60 percent more likely to be diagnosed with ADHD than the oldest children in the same grade. Similarly, when that group of classmates reached the fifth and eighth grades, the youngest were more than twice as likely to be prescribed stimulants.

Overall, the study found that about 20 percent – or 900,000 – of the 4.5 million children currently identified as having ADHD likely have been misdiagnosed.

Monarch Migration Research

Monarch Butterfly

Monarch butterflies – renowned for their lengthy annual migration to and from Mexico – complete an even more spectacular journey home than previously thought.

New research from the University of Guelph reveals that some North American monarchs born in the Midwest and Great Lakes fly directly east over the Appalachians and settle along the eastern seaboard. Previously, scientists believed the majority of monarchs migrated north directly from the Gulf Coast.

Unfortunately the press release doesn’t provide a link to the study – maybe it is not open science. Often organization focused on closed science don’t do well providing web links (though even open science organizations fall down on this more than they should).

“It solves the long-standing mystery of why monarchs always show up later on the east coast compared to the interior,” he said. “Importantly, it means that the viability of east coast populations is highly dependent upon productivity on the other side of the mountains.”

Monarchs travel thousands of kilometres each year from wintering sites in central Mexico back to North America’s eastern coast, a journey that requires multiple generations (in the same year) produced at various breeding regions.

Biologists had suspected that monarchs fly back from Mexico west-to-east over the Appalachians, but no evidence existed to support the theory. “Ours is the first proof of longitudinal migration,” Miller said.

For the study, the researchers collected 90 monarch samples from 17 sites between Maine and Virginia in June and July of 2009. They also collected 180 samples of milkweed (the only plant monarch larvae can eat) from 36 sites along the eastern coast between May and July of that year.

They then used hydrogen and carbon isotope measurements to determine when and where the monarchs were born. Isotope values in milkweed vary longitudinally and can be measured in monarch wings, Miller said. The researchers discovered that 88 per cent of the monarchs sampled originated in the Midwest and Great Lakes regions.

“This means that the recolonization of the east coast is by second-generation monarchs that hatched around the Great Lakes and then migrated eastward over the Appalachians,” Miller said. “We must target the Great Lakes region to conserve the east coast monarch populations.”

Full press release

Google Research Awards

Google Faculty Research Awards, support full-time faculty pursuing research. The most recent quarterly funding totals over $4 million in 75 awards across 18 different areas. The areas that received the highest level of funding for this round were systems and infrastructure, human computer interaction, multimedia and security. In this round, 26 percent of the funding was awarded to universities outside the U.S.

Some examples

Erik Brynjolfsson, Massachusetts Institute of Technology. The Future of Prediction – How Google Searches Foreshadow Housing Prices and Quantities (Economics and market algortihms): How data from search engines like Google provide a highly accurate but simple way to predict future business activities.
John Quinn, Makerere University, Uganda. Mobile Crop Surveillance in the Developing World (Multimedia search and audio/video processing): A computer vision system using camera-enabled mobile devices to monitor the spread of viral disease among staple crops.
Ronojoy Adhikari, The Institute of Mathematical Sciences, India (probably this is the person, why doesn’t google include a link to these people’s sites?). Machine Learning of Syntax in Undeciphered Scripts (Machine learning): Devise algorithms that would learn to search for evidence of semantics in datasets such as the Indus script.
Jennifer Rexford, Princeton. Rethinking Wide-Area Traffic Management (Software and hardware systems infrastructure): Drawing on mature techniques from optimization theory, design new traffic-management solutions where the hosts, routers, and management system cooperate in a more effective way.

Smart companies realize great research is done in universities that should be adlopted by companies. Many companies listen to fools that talk of academic research as not “real world.” Companies like Google do well for many reasons but one is they pay more attention to scientific research than wall street research. More companies would benefit from adopting this leadership style from Google. Google also continues to fund and support research.

Parasites in the Gut Help Develop a Healthy Immune System

It has long been known that microbes in the gut help to develop a healthy immune system, hence the rise in popularity of probiotic yoghurts that encourage ‘friendly’ bacteria. But new research by Professors Richard Grencis and Ian Roberts shows that larger organisms such as parasitic worms are also essential in maintaining our bodily ‘ecosystem’. “The worms have been with us throughout our evolution and their presence, along with bacteria, in the ecosystem of the gut is important in the development of a functional immune system.”

Parasite Rex is a great book, I have written about previously looking at parasites and their affect on human health.

Professor Grencis adds: “If you look at the incidence of parasitic worm infection and compare it to the incidence of auto-immune disease and allergy, where the body’s immune system over-reacts and causes damage, they have little overlap. Clean places in the West, where parasites are eradicated, see problems caused by overactive immune systems. In the developing world, there is more parasitic worm infection but less auto-immune and allergic problems.

“We are not suggesting that people deliberately infect themselves with parasitic worms but we are saying that these larger pathogens make things that help our immune system. We have evolved with both the bugs and the worms and there are consequences of that interaction, so they are important to the development of our immune system.”

Whipworm, also known as Trichuris, is a very common type of parasitic worm and infects many species of animals including millions of humans. It has also been with us and animals throughout evolution. The parasites live in the large intestine, the very site containing the bulk of the intestinal bacteria.

Heavy infections of whipworm can cause bloody diarrhoea, with long-standing blood loss leading to iron-deficiency anaemia, and even rectal prolapse. But light infections have relatively few symptoms.
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Students Will Spend Year Doing Career-Changing Research Thanks to HHMI

This year, 116 medical, dental, and veterinary students from 47 schools across the country will take a break from memorizing molecular metabolism and studying drug interactions to spend a year in a lab doing hands-on research. The break from regular coursework, funded through a $4 million Howard Hughes Medical Institute (HHMI) initiative, is intended to give students an opportunity to immerse themselves in science and consider whether they want to pursue a career as a physician-scientist.

Nearly 500 medical students applied for the research year through the HHMI-National Institutes of Health (NIH) Medical Research Scholars and HHMI Medical Research Fellows programs. Both efforts seek to strengthen and expand the pool of medically-trained researchers. The funding HHMI provides is a great resource.

“We want medical, dental, and veterinary students to become immersed in the life of academic science for at least a year. And we hope they get so engaged in the process and life of scientific research that they will decide to continue it for the rest of their lives,” says Peter Bruns, HHMI’s vice president for grants and special programs. “We need more doctors who do basic research to improve human health.”

As part of its commitment to fostering the translation of basic research discoveries into improved diagnoses and treatments, HHMI has developed a range of programs to nurture the careers of researchers who bridge the gap between clinical medicine and basic science. In addition to the programs for medical students, the Institute supports medical training for Ph.D. students in the basic sciences and has made specific efforts to fund top physician-scientists as HHMI investigators.

The medical research scholars and fellows programs are open to medical, dental, and veterinary students enrolled in U.S. schools. Most have completed the second or third year of their professional program when they spend a year working in a lab either at the NIH or at an academic medical center or research university they select. During the last 25 years, more than 2,100 students have participated.

The HHMI Medical Research Fellowships program allows medical, dental, and veterinary students to pursue biomedical research at a laboratory anywhere in the United States except the NIH campus in Bethesda. Each student submits a research plan to work in a specific lab with a mentor they have identified. Since 1989, about 1,200 students have participated.

This year, 74 students from 26 medical schools and two veterinary schools were chosen as fellows from a pool of 274. While most students elect to stay at their home institution to do their research, this year 17 fellows will work in labs at a different school. Their research topics include schizophrenia, wound healing, organ development, and many other important biological questions.

The HHMI-NIH Research Scholars program was established in 1985 to encourage medical students to pursue research by allowing them to take a year off from their medical studies. The program has since been expanded to include dental and veterinary students. It has enabled about 1,000 students to work in NIH labs.

Students selected as research scholars often enter the program with only a general idea of what type of research they would like to do. As soon as they are accepted, they begin researching the more than 1,100 laboratories at NIH. They meet with a number potential mentors before finalizing which project to pursue under the guidance of their NIH advisor and HHMI’s staff. The students are sometimes called “cloister scholars” because they live in apartments or dorm-style rooms in a refurbished cloister on the NIH campus in Bethesda.

This year, 42 students from 28 medical schools and one veterinary school were chosen as research scholars. More than 200 students from 93 schools applied.

Variation in Human DNA

Variation on the order of thousands to hundreds of thousands of DNA’s smallest pieces – large swaths varying in length or location or even showing up in reverse order – appeared 4,205 times in a comparison of DNA from just four people.

Those structural differences popped into clear view through computer analysis of more than 500 linear feet of DNA molecules analyzed by the powerful genome mapping system developed over nearly two decades by David C. Schwartz, professor of chemistry and genetics at UW-Madison.

“We probably have the most comprehensive view of the human genome ever,” Schwartz says. “And the variation we’re seeing in the human genome is something we’ve known was there and important for many years, but we haven’t been able to fully study it.”

To get a better picture of those structural variations, Schwartz and his team developed the Optical Mapping System, a wholly new type of genome analysis that directly examines millions of individual DNA molecules.

“Our newer genome analysis systems, if commercialized, promise genome analysis in one hour, at under $1,000,” Schwartz says. “And we require that high speed and low cost to power the new field of personal genomics.”

Read full press release

Green Technology Innovation by College Engineering Students

With prizes totaling more than $100,000 in value, this year’s Climate Leadership Challenge is believed to be the most lucrative college or university competition of its kind in the country. The contest was open to all UW-Madison students.

A device that would help provide electricity efficiently and at low cost in rural areas of developing countries took the top prize – $50,000 – this week in a student competition at the University of Wisconsin-Madison for innovative ideas to counteract climate change.

The “microformer” is the brainchild of Jonathan Lee, Dan Ludois, and Patricio Mendoza, all graduate students in electrical engineering. Besides the cash prize, they will receive a promotional trip worth $5,000 and an option for a free one-year lease in the University Research Park’s new Metro Innovation Center on Madison’s east side.

“We really want to see implementation of the best ideas offered,” said Tracey Holloway, director of the Nelson Institute Center for Sustainability and the Global Environment at UW-Madison, which staged the contest for the second year in a row. “The purpose of this competition is to make an impact on climate change.”

The runner-up for the “most action-ready idea” was a proposal to promote the use of oil from Jatropha curcas plants to fuel special cooking stoves in places like Haiti. UW-Madison seniors Eyleen Chou (mechanical engineering), Jason Lohr (electrical engineering), Tyler Lark (biomedical engineering/mathematics) won $10,000 for their scheme to reduce deforestation by lowering demand for wood charcoal as a cooking fuel.

CORE Concept, a technology that would cut emissions from internal combustion engines by using a greater variety of fuels, won mechanical engineering doctoral students Sage Kokjohn, Derek Splitter, and Reed Hanson $15,000 as the “most innovative technical solution.”

SnowShoe, a smart phone application that would enable shoppers to check the carbon footprint of any item in a grocery store by scanning its bar code, won $15,000 as the “most innovative non-technical solution.” Graduate students Claus Moberg (atmospheric and oceanic science), Jami Morton (environment and resources), and Matt Leudtke (civil and environmental engineering) submitted the idea.

Other finalists were REDCASH, a plan to recycle desalination wastewater for carbon sequestration and hydrogen fuel production, by doctoral student Eric Downes (biophysics) and senior Ian Olson (physics/engineering physics); and Switch, an energy management system that integrates feedback and incentives into social gaming to reduce personal energy use, by doctoral students David Zaks (environment and resources) and Elizabeth Bagley (environment and resources/educational psychology).