Tag Archives: webcasts

Roger Tsien Lecture On Green Florescent Protein

Nobel Laureate Roger Tsien discusses his research on green florescent protein. From the Nobel Prize web site:

n the 1960s, when the Japanese scientist Osamu Shimomura began to study the bioluminescent jelly-fish Aequorea victoria, he had no idea what a scientific revolution it would lead to. Thirty years later, Martin Chalfie used the jellyfish’s green fluorescent protein to help him study life’s smallest building block, the cell.

when Anton van Leeuwenhoek invented the microscope in the 17th century a new world opened up. Scientists could suddenly see bacteria, sperm and blood cells. Things they previously did not know even existed. This year’s Nobel Prize in Chemistry rewards a similar effect on science. The green fluorescent protein, GFP, has functioned in the past decade as a guiding star for biochemists, biologists, medical scientists and other researchers.

This is where the third Nobel Prize laureate Roger Tsien makes his entry. His greatest contribution to the GFP revolution was that he extended the researchers’ palette with many new colours that glowed longer and with higher intensity.

To begin with, Tsien charted how the GFP chromophore is formed chemically in the 238-amino-acid-long GFP protein. Researchers had previously shown that three amino acids in position 65–67 react chemically with each other to form the chromosphore. Tsien showed that this chemical reaction requires oxygen and explained how it can happen without the help of other proteins.

With the aid of DNA technology, Tsien took the next step and exchanged various amino acids in different parts of GFP. This led to the protein both absorbing and emitting light in other parts of the spectrum. By experimenting with the amino acid composition, Tsien was able to develop new variants of GFP that shine more strongly and in quite different colours such as cyan, blue and yellow. That is how researchers today can mark different proteins in different colours to see their interactions.

Related: The Nobel Prize in Chemistry 2008Nobel Laureate Initiates Symposia for Student ScientistsNobel Prize in Chemistry (2006)

Botball 2009 Finals

Webcast of the double elimination rounds of the Botball 2009 competition of the winning Alcott Middle School Botball team. Norman teens win robotics contest:

The challenge of building the robot and seeing it do what it’s programmed to do is very exciting, said Goree, 14. “I like figuring out what’s wrong with the robots, fixing them and then seeing them work after you fix them,” he said.

The team was shocked, excited and proud of their first-place finish, they said. “Almost all the teams we played against were high school teams, so that was pretty exciting for us, beating high schoolers,” Goree said.

Related: Robo-One Grand Championship in TokyoFIRST Robotics in MinnesotaRoboCup: Robot Football (Soccer)

Friday Fun: Dolphins Play with Air Bubble Rings

Bubbles in water

The bubble is the most stable situation for an amount of gas phase in water (liquid phase). A surface tension is associated with the surface between the gas phase and the liquid phase, the surface tension tends to minimize the surface area. This is also described in the section on bubbles in bubble models. Given a volume of gas, the sphere (bubble) shape is the shape that has the smallest surface area with respect to the containing volume.

The situation of a bubble in water is comparable to a balloon. The balloon surface is elastic. The tension of it tries to minimize the surface: if you don’t tie a knot in the balloon after blowing it up, air escapes and the surface of the balloon is minimized to the initial unstretched situation.

Bubbles do not turn into rings naturally. Something has to be done for that. However, they have long lives and often make it up to the surface. Hence they are stable structures.

Dolphins create bubble rings by blowing air in a water vortex ring: by flipping a fin they create a vortex ring of water. The then blow air in the ring, which goes to the center of the vortex ring. In the water vortex ring the natural location of the air is in the center of the vortex. When air and water move in a circular path like they do in the vortex ring, air and water are separated due to the centripetal force. Since density of water is larger than air, water moves at the outside, while the air ends up in the middle.

Follow the link for much more on the physics of bubble rings.

Related: Colored BubblesDolphins Using Tools to HuntDo Dolphins Sleep?posts on animals

Google Wave Developer Preview Webcast

Google Wave is a new tool for communication and collaboration on the web, coming later this year. The presentation was given at Google I/O 2009. The demo shows what is possible in a HTML 5 browser. They are developing this as an open access project. The creative team is lead by the creators for Google Maps (brothers Lars and Jens Rasmussen) and product manager Stephanie Hannon.

A wave is equal parts conversation and document. People can communicate and work together with richly formatted text, photos, videos, maps, and more.

A wave is shared. Any participant can reply anywhere in the message, edit the content and add participants at any point in the process. Then playback lets anyone rewind the wave to see who said what and when.

A wave is live. With live transmission as you type, participants on a wave can have faster conversations, see edits and interact with extensions in real-time.

Very cool stuff. The super easy blog interaction is great. And the user experience with notification and collaborative editing seems excellent. The playback feature to view changes seems good though that is still an area I worry about on heavily collaborative work. Hopefully they let you see like all change x person made, search changes…

They also have a very cool context sensitive spell checker that can highlight mis-spelled words that are another dictionary word but not right in the context used (about 44:30 in the webcast).

For software developer readers they also highly recommended the Google Web Development Kit, which they used heavily on this project.

Related: Joel Spolsky Webcast on Creating Social Web ResourcesRead the Curious Cat Science and Engineering Blog in 35 LanguagesLarry Page and Sergey Brin Interview WebcastGoogle Should Stay True to Their Management Practices

Went Walkabout. Brought back Google Wave.
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Intel Science and Engineering Fair 2009 Webcasts

Tara Adiseshan, 14, of Charlottesville, Virginia; Li Boynton, 17, of Houston; and Olivia Schwob, 16, of Boston were selected from 1,563 young scientists from 56 countries, regions and territories for their commitment to innovation and science. Each received a $50,000 scholarship from the Intel Foundation.

(video removed, so the embed code has been removed)

In the webcast, Tara Adiseshan, talks about her project studying the evolutionary ties between nematodes (parasites) and sweat bees. She identified and classified the evolutionary relationships between sweat bees and the nematodes (microscopic worms) that live inside them. Tara was able to prove that because the two have such ecologically intimate relationships, they also have an evolutionary relationship. That is to say, if one species evolves, the other will follow.

Li Boynton developed a biosensor from bioluminescent bacteria (a living organism that gives off light) to detect the presence of contaminants in public water. Li’s biosensor is cheaper and easier to use than current biosensors, and she hopes it can be used in developing countries to reduce water toxicity. Li Boynton on What’s Great About Science:

Olivia Schwob isolated a gene that can be used to improve the intelligence of a worm. The results could help us better understand how humans learn and even prevent, treat and cure mental disabilities in the future.

In addition to the three $50,000 top winners, more than 500 Intel International Science and Engineering Fair participants received scholarships and prizes for their groundbreaking work. Intel awards included 19 “Best of Category” winners who each received a $5,000 Intel scholarship and a new laptop. In total, nearly $4 million is scholarships and awards were provided.

Related: Intel ISEF 2009 Final GalaGirls Sweep Top Honors at Siemens Competition in Math, Science and TechnologyIntel International Science and Engineering Fair 2007Worldwide Science Wizkids at Intel ISEF2008 Intel Science Talent Search
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Meeting the Challenge of Simplicity

Interesting webcast by Meeting the Challenge of Simplicity by Giles Colborne. This session addresses abstract notion of simplicity, looks at why it is critical in modern UI design and answers questions: Why does simplicity matter? Is there a meaningful definition of simplicity? Why do design processes and good intentions undermine simplicity? What processes and techniques can software developers use to achieve simplicity?

InfoQ is a great site for watching presentations online. With a simple but superior interface showing a live video with a separate area showing the current slides.

Related: posts on usabilityDesigning In ErrorsUsability FailuresEngineering a Better World: Bike Corn-ShellerComplicating Simplicity

Friday Fun: Bird Using Bait to Fish

In the webcast an Aukuu bird (Black-crowned Night Heron) fishes using bread as bait. They normally hunt by waiting at the side of a lake and fishing. This individual learned how to bait the fish with bread and improve the fishing results. It also passed on that method to other birds that learned how to use the bait method themselves.

Another bird using bait (with turtles trying to get the bait) and another bird using bait (with a stork trying to steal the fish). And another one. The videos seem to be different species of birds to me.

Related: Orangutan Attempts to Hunt Fish with SpearDolphins Using Tools to HuntBird Brain experimentposts on animals